Zobrazeno 1 - 10
of 3 002
pro vyhledávání: '"Ocular drug delivery"'
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 10, Pp 1569-1575 (2024)
The complex barriers to drug delivery in the eye make it difficult for traditional ophthalmic preparations to reach pathological tissues in the posterior segment of the eye via ocular surface. Therefore, intravitreal drug injection has been widely us
Externí odkaz:
https://doaj.org/article/973551893fcc4085b00f1a91f7a9821b
Autor:
Umer Mushtaq Bhat, Nisar Ahmad Khan, Syed Naiem Raza, Mohammad Ali, Seema Mehdi, Ishfaq Mohiuddin, Faiyaz Shakeel, Zulfikar Ali Bhat, Ghulam Nabi Bader, Ishtiaq Ahmad Chashoo, Shahid Ud Din Wani
Publikováno v:
Heliyon, Vol 10, Iss 22, Pp e38777- (2024)
Ocular drugs have low absorption because of the unique environment in the eye, making ocular drugs one of the most challenging pharmaceutical initiatives. Liposomes have shown to be a promising ocular drug delivery system over the years because of en
Externí odkaz:
https://doaj.org/article/59f288f381084ef097285754ef11c43c
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101229- (2024)
Glaucoma presents a significant global health concern and affects millions of individuals worldwide and predicted a high increase in prevalence of about 111 million by 2040. The current standard treatment involves hypotensive eye drops; however, chal
Externí odkaz:
https://doaj.org/article/94b8fb13384c4a90bb0e14134a3a329a
Autor:
Mirza Salman Baig, Shweta Kulkarni Karade, Anas Ahmad, Mohd. Ashif Khan, Anzarul Haque, Thomas J. Webster, Md. Faiyazuddin, Noora H. Al-Qahtani
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Ocular drug delivery presents significant challenges due to intricate anatomy and the various barriers (corneal, tear, conjunctival, blood-aqueous, blood-retinal, and degradative enzymes) within the eye. Lipid-based nanoparticles (LNPs) have emerged
Externí odkaz:
https://doaj.org/article/697d7a451002441286763e89e0d57094
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 4045-4060 (2024)
Wei Wei,1,2,* Haili Cao,2,* Di Shen,2 Xiyu Sun,2 Zhenzhen Jia,1 Mingzhen Zhang1 1School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, 710061, People’s Republic of China; 2Xi’an No.1 Hospit
Externí odkaz:
https://doaj.org/article/969cd46c20d849209f6d27089dba280a
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
The application of ketoconazole (KET) in ocular drug delivery is restricted by its poor aqueous solubility though its broad-spectrum antifungal activity. The aim of this study is to develop an ion-sensitive in situ gel (ISG) of KET to promote its ocu
Externí odkaz:
https://doaj.org/article/a6661559ca6046229fb77cb264057066
Autor:
Bryce Chiang, Kathleen Heng, Kyeongwoo Jang, Roopa Dalal, Yaping Joyce Liao, David Myung, Jeffrey L Goldberg
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
Purpose Targeted drug delivery to the optic nerve head may be useful in the preclinical study and later clinical management of optic neuropathies, however, there are no FDA-approved drug delivery systems to achieve this. The purpose of this work was
Externí odkaz:
https://doaj.org/article/c5eceb5501e04f5fb96fb6fec131c03d
Autor:
Sanaul Mustafa
Publikováno v:
German Journal of Pharmaceuticals and Biomaterials, Vol 3, Iss 3 (2024)
The unique anatomy and physiology of the eye present significant challenges for effective drug delivery, necessitating innovative approaches to manage ocular diseases. This review examines the intricate structure of the eye and the barriers that impe
Externí odkaz:
https://doaj.org/article/1bab82132de7484d83ffdcdd50ef97c1
Autor:
Stefana Duca, Naa Dei Nikoi, Madeline Berrow, Lois Barber, Louise N. Slope, Anna F.A. Peacock, Felicity de Cogan
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35109- (2024)
Oligoarginine cell-penetrating peptides (CPPs) are short peptides that can enhance drug delivery into cells and are of particular interest in ocular topical formulations for age-related macular degeneration (AMD) treatments. The length and structural
Externí odkaz:
https://doaj.org/article/e19fb43b659b4f8684a91488cf7991d8
Autor:
Rongyue Xue, Hao Wu, Siyu Li, Ning Pu, Dong Wei, Na Zhao, Yongheng Cui, Haoyan Li, Zongming Song, Ye Tao
Publikováno v:
Materials Today Bio, Vol 27, Iss , Pp 101126- (2024)
Posterior segment disease acts as a major cause of irreversible visual impairments. Successful treatment of posterior segment disease requires the efficient delivery of therapeutic substances to the targeted lesion. However, the complex ocular archit
Externí odkaz:
https://doaj.org/article/39d8977d7bbd4cee9182b4835bd6dbf2