The High-Altitude Water Cherenkov (HAWC) Observatory in M\'exico: The Primary Detector

Autor: Abeysekara, A. U., Albert, A., Alfaro, R., Álvarez, C., Álvarez, J. D., Araya, M., Arteaga-Velázquez, J. C., Arunbabu, K. P., Rojas, D. Avila, Solares, H. A. Ayala, Babu, R., Barber, A. S., Becerril, A., Belmont-Moreno, E., BenZvi, S. Y., Blanco, O., Braun, J., Brisbois, C., Caballero-Mora, K. S., Martínez, J. I. Cabrera, Capistrán, T., Carramiñana, A., Casanova, S., Castillo, M., Chaparro-Amaro, O., Cotti, U., Cotzomi, J., de León, S. Coutiño, de la Fuente, E., de León, C., De Young, T., Hernández, R. Díaz, Dingus, B. L., DuVernois, M. A., Durocher, M., Díaz-Vélez, J. C., Ellsworth, R. W., Engel, K., Espinoza, C., Fan, K. L., Fang, K., Fick, U. B., Fleischhack, H., Flores, J. L., Fraija, N., García-González, J. A., García-Torales, G., Garfias, F., Giacinti, G., Goksu, H., González, M. M., González-Muñoz, A., Goodman, J. A., Harding, J. P., Hernández, E., Hernández, S., Hinton, J., Hona, B., Huang, D., Hueyotl-Zahuantitla, F., Hui, C. M., Humensky, T. B., Hüntemeyer, P., Iriarte, A., Imran, A., Jardin-Blicq, A., Joshi, V., Kaufmann, S., Kieda, D., Kunde, G. J., Lara, A., Lauer, R., Lee, W. H., Lennarz, D., Vargas, H. León, Linnemann, J. T., Longinotti, A. L., Luis-Raya, G., Lundeen, J., Malone, K., Marandon, V., Marinelli, A., Martínez, O., Martínez-Castellanos, I., Martínez-Castro, J., Martínez-Huerta, H., Matthews, J. A., Miranda-Romagnoli, P., Montaruli, T., Morales-Soto, J. A., Moreno, E., Mostafá, M., Nayerhoda, A., Nellen, L., Newbold, M., Nisa, M. U., Noriega-Papaqui, R., Oceguera-Becerra, T., Olivera-Nieto, L., Omodei, N., Peisker, A., Araujo, Y. Pérez, Pérez-Pérez, E. G., Ponce, E., Pretz, J., Rho, C. D., Rosa-González, D., Ruiz-Velasco, E., Salazar, H., Salazar-Gallegos, D., Greus, F. Salesa, Sandoval, A., Schneider, M., Schoorlemmer, H., Serna-Franco, J., Sinnis, G., Smith, A. J., Son, Y., Woodle, K. Sparks, Springer, R. W., Taboada, I., Tepe, A., Tibolla, O., Tollefson, K., Torres, I., Torres-Escobedo, R., Turner, R., Ureña-Mena, F., Ukwatta, T. N., Varela, E., Vargas-Magaña, M., Villaseñor, L., Wang, X., Watson, I. J., Werner, F., Westerhoff, S., Willox, E., Wisher, I., Wood, J., Yodh, G. B., Zaborov, D., Zepeda, A., Zhou, H.

Publikováno v: Nuclear Inst. and Methods in Physics Research, A (2023) 168253

The High-Altitude Water Cherenkov (HAWC) observatory is a second-generation continuously operated, wide field-of-view, TeV gamma-ray observatory. The HAWC observatory and its analysis techniques build on experience of the Milagro experiment in using

Externí odkaz: http://arxiv.org/abs/2304.00730

Implementing Standard Diagnosis and Treatment for Locally Advanced Breast Cancer Through Global Research in Latin America: Results From a Multicountry Pragmatic Trial

Autor: Javier Retamales, Adrián Daneri-Navarro, Nora Artagaveytia, Daniela Alves da Quinta, Eliana Abdelhay, Osvaldo L. Podhajcer, Carlos Velázquez, Diego Giunta, Susanne Crocamo, Adriana Garibay-Escobar, Alicia Del Toro-Arreola, Robinson Rodriguez, Marta Aghazarian, Elsa Alcoba, Isabel Alonso, Renata Binato, Alicia I. Bravo, Juan Canton-Romero, Dirce M. Carraro, Mónica Castro, Juan Castro-Cervantes, Sandra Cataldi, Natalia Camejo, Laura Cortes-Sanabria, Maria Flores-Marquez, Guillermo Laviña, Eduardo Musetti, Benedicta Caserta, Mauricio Cerda, Alicia Colombo, Raul Delgadillo-Cristerna, Marisa Dreyer Breitenbach, Elmer Fernandez, Jorge Fernandez, Ramon Franco-Topete, Carolina Gabay, Fancy Gaete, Jorge Gamboa, Ricardo García-Gaeta, Mariana Gomez del Toro, Leivy P. Gonzalez-Ramirez, Marisol Guerrero, Manuel Herrera-Miramontes, Alejandra Lopez-Vasquez, Silvina Maldonado, Andrés Morán-Mendoza, Gilberto Morgan-Villela, Maria Aparecida Nagai, Nancy Navarro-Ruiz, Antonio Oceguera-Villanueva, Miguel Angel Ortiz, Jael Quintero, Antonio Quintero-Ramos, Gladys Ramirez-Rosales, Maritza Ramos-Ramirez, Marcia Maria Chiquitelli Marques, Ernesto Rivera Claisse, Diego Rodriguez-Gonzalez, Ana Romero-Gomez, Cristina Rosales, Efraín Salas-Gonzalez, Verónica Sanchotena, Laura Segovia, Aída A. Silva-García, Olivia Valenzuela-Antelo, Laura Venegas-Godinez, Livia Zagame, Jorge Gomez, Andrea S. Llera, Bettina Müller

Publikováno v: JCO Global Oncology, Vol , Iss 10 (2024)

PURPOSEBreast cancer mortality rates in Latin America (LA) are higher than those in the United States, possibly because of advanced disease presentation, health care disparities, or unfavorable molecular subtypes. The Latin American Cancer Research N

Externí odkaz: https://doaj.org/article/b2f72577487d4b14a83f1ea247073b38

Characterization of flavonoids with potent and subtype-selective actions on estrogen receptors alpha and beta

Autor: Michael J. Bolt, Jessica Oceguera, Pankaj K. Singh, Kazem Safari, Derek H. Abbott, Kaley A. Neugebauer, Maureen G. Mancini, Daniel A. Gorelick, Fabio Stossi, Michael A. Mancini

Publikováno v: iScience, Vol 27, Iss 3, Pp 109275- (2024)

Summary: The initial step in estrogen-regulated transcription is the binding of a ligand to its cognate receptors, named estrogen receptors (ERα and ERβ). Phytochemicals present in foods and environment can compete with endogenous hormones to alter

Externí odkaz: https://doaj.org/article/f27ba319ca7e4cc1b5641920f2a19da6

Characterization of flavonoids with potent and subtype-selective actions on estrogen receptors alpha and beta

Autor: Bolt, Michael J., Oceguera, Jessica, Singh, Pankaj K., Safari, Kazem, Abbott, Derek H., Neugebauer, Kaley A., Mancini, Maureen G., Gorelick, Daniel A., Stossi, Fabio, Mancini, Michael A.

Publikováno v: In iScience 15 March 2024 27(3)

Patterned PVA Hydrogels with 3D Petri Dish® Micro-Molds of Varying Topography for Spheroid Formation of HeLa Cancer Cells: In Vitro Assessment

Autor: Maira Moreno Valtierra, Adriana Urue Corral, Jorge Armando Jiménez-Avalos, Erika Barbosa Avalos, Judith Dávila-Rodríguez, Norma Morales Hernández, Mauricio Comas-García, Guillermo Toriz González, Antonio Oceguera-Villanueva, José Alfonso Cruz-Ramos, Rodolfo Hernández Gutiérrez, Moisés Martínez Velázquez, Zaira Yunuen García Carvajal

Publikováno v: Gels, Vol 10, Iss 8, p 518 (2024)

Cell spheroids are an important three-dimensional (3D) model for in vitro testing and are gaining interest for their use in clinical applications. More natural 3D cell culture environments that support cell–cell interactions have been created for c

Externí odkaz: https://doaj.org/article/c3d49376df684c00914f115ba848aa27