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Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1623 (2023)
The authors and the journal retract the article, ‘Pyrvinium Treatment Confers Hepatic Metabolic Benefits via β-Catenin Downregulation and AMPK Activation’ [...]
Externí odkaz:
https://doaj.org/article/f8feec583d7b44c480883805690575f3
Publikováno v:
Pharmaceutics, Vol 13, Iss 4, p 537 (2021)
Coordinated transcellular transport by the uptake via organic cation transporters (OCTs) in concert with the efflux via multidrug and toxin extrusion proteins (MATEs) is an essential system for hepatic and renal drug disposition. Despite their clinic
Externí odkaz:
https://doaj.org/article/472a90c0313b4444a633c31968550676
Publikováno v:
Pharmaceutics, Vol 13, Iss 3, p 330 (2021)
Genetic evidence has indicated that β-catenin plays a vital role in glucose and lipid metabolism. Here, we investigated whether pyrvinium, an anthelmintic agent previously reported as a down-regulator of cellular β-catenin levels, conferred any met
Externí odkaz:
https://doaj.org/article/7bdac96e2bac478999ecdbcf2934411f
Autor:
Francisca Abumchukwu Okoli, Nancy Amalachukwu Mbachu, Ugoy Sonia Ogbonna, Amaka Olivia Obianom, Augustine Ebele Mbachu
Publikováno v:
Asian Journal of Agricultural and Horticultural Research. :1-16
Plant diseases accounts for huge losses in agriculture. To ensure food security and sustainability, an agricultural yield must be improved to meet the growing world population. Due to growing awareness of the effect of pesticides and herbicides on hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eec3dcf64ff3b1db28005a21bdc86a3e
https://doi.org/10.9734/ajahr/2022/v9i130132
https://doi.org/10.9734/ajahr/2022/v9i130132
Autor:
D. Sivakumar, C. Obianom
Publikováno v:
Acta Horticulturae. :65-72
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaff6cc91402e55eb1baec9429c3e7a0
https://doi.org/10.17660/actahortic.2021.1323.11
https://doi.org/10.17660/actahortic.2021.1323.11
Publikováno v:
Clinical Pharmacology & Therapeutics. 108:107-115
Pharmacokinetic (PK) similarity studies are vital to assess the biosimilarity of a biosimilar to a reference product. Systematic bias in a bioanalytical method that quantify products could be a potential source of error affecting the variability of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d0e66c0238720e44a0502c774b5915
https://doi.org/10.1002/cpt.1767
https://doi.org/10.1002/cpt.1767
Autor:
Abdelrazik, Ahmed, Koya, Abdulmalik, Chauhan, Reshma, Obianom, Ekenedirichukwu, Li, Xin, Ng, G. Andre
Publikováno v:
In Heart Rhythm May 2024 21(5) Supplement:S302-S302
Publikováno v:
Scientia Horticulturae. 254:1-6
Species of Penicillium (blue mould) and Monilinia (brown rot) are major causes of postharvest loss of stone fruit. Breeding for resistance to these pathogens is a sustainable option that could reduce over reliance on postharvest chemical intervention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::def2dc48ff6a67b3c5a4b5ea9434d411
https://doi.org/10.1016/j.scienta.2019.04.067
https://doi.org/10.1016/j.scienta.2019.04.067
Autor:
Yao Chen, Qing Zhao, Guang-Hui Lian, Li-jie Chen, Jing Guo, Jian Xiao, Dong Guo, Yan Shu, Wei Zhang, Shi-Fang Peng, Xiu-Xian Lin, Obinna N. Obianom, Hong Yang, Dan Chen, Ying Xu
Publikováno v:
Archives of Toxicology. 93:1679-1695
Low-density lipoprotein receptor-related protein 6 (LRP6) is an important coreceptor in the Wnt/β-catenin upstream signaling pathway. Rs2302685 is a common functional mutation of LRP6 that has been previously associated with reduced alcoholic liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42bd8a05d876506ef02c67cb2110a05
https://doi.org/10.1007/s00204-019-02447-0
https://doi.org/10.1007/s00204-019-02447-0