Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Oates, Andrew C."'
Notch signaling is a ubiquitous and versatile intercellular signaling system that drives collective behaviors and pattern formation in biological tissues. During embryonic development, Notch is involved in generation of collective biochemical oscilla
Externí odkaz:
http://arxiv.org/abs/2408.04027
Autor:
Negrete Jr, Jose, Oates, Andrew C.
Publikováno v:
Phys. Rev. E 99, 042417 (2019)
Cellular checkerboard patterns are observed at many developmental stages of embryos. We study an analytically tractable model for lateral inhibition and show that a coupling coefficient with a negative value is sufficient to obtain noisy or periodic
Externí odkaz:
http://arxiv.org/abs/1808.09362
Akademický článek
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Publikováno v:
Physical Biology 13, 05LT03 (2016)
Rhythmic and sequential segmentation of the embryonic body plan is a vital developmental patterning process in all vertebrate species. However, a theoretical framework capturing the emergence of dynamic patterns of gene expression from the interplay
Externí odkaz:
http://arxiv.org/abs/1610.03416
Publikováno v:
Papers in Physics 6, 060012 (2014)
We study the effects of multiple binding sites in the promoter of a genetic oscillator. We evaluate the regulatory function of a promoter with multiple binding sites in the absence of cooperative binding, and consider different hypotheses for how the
Externí odkaz:
http://arxiv.org/abs/1501.04040
Akademický článek
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We study systems of identical coupled oscillators introducing a distribution of delay times in the coupling. For arbitrary network topologies, we show that the frequency and stability of the fully synchronized states depend only on the mean of the de
Externí odkaz:
http://arxiv.org/abs/1206.2288
Publikováno v:
Phys. Rev. Lett. 108, 204101 (2012)
We study the effects of delayed coupling on timing and pattern formation in spatially extended systems of dynamic oscillators. Starting from a discrete lattice of coupled oscillators, we derive a generic continuum theory for collective modes of long
Externí odkaz:
http://arxiv.org/abs/1205.4127
Publikováno v:
Physical Biology 9 (2012) 036006
Cell movement and intercellular signaling occur simultaneously during the development of tissues, but little is known about how movement affects signaling. Previous theoretical studies have shown that faster moving cells favor synchronization across
Externí odkaz:
http://arxiv.org/abs/1205.1425
Autor:
Herrgen, Leah, Ares, Saul, Morelli, Luis G., Schroeter, Christian, Julicher, Frank, Oates, Andrew C.
Publikováno v:
Current Biology 20, 1244-1253 (2010)
Coupled biological oscillators can tick with the same period. How this collective period is established is a key question in understanding biological clocks. We explore this question in the segmentation clock, a population of coupled cellular oscilla
Externí odkaz:
http://arxiv.org/abs/1009.0456