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pro vyhledávání: '"Oana, Kubinyecz"'
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Chronic otitis media (OM) is the most common cause of hearing loss worldwide, yet the underlying genetics and molecular pathology are poorly understood. The mouse mutant Jeff is a single gene mouse model for OM identified from a deafness screen as pa
Externí odkaz:
https://doaj.org/article/749d241dfcd341cdbd97992d5a1f73c1
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Zygotic genome activation (ZGA) represents the initiation of transcription following fertilisation. Despite its importance, we know little of the molecular events that initiate mammalian ZGA in vivo. Recent in vitro studies in mouse embryonic stem ce
Zygotic Genome Activation (ZGA) represents the initiation of transcription following fertilisation. Despite its importance in shifting developmental control from primarily maternal stores in the oocyte to the embryo proper, we know little of the mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e96d9dd7b26d5580ec57c039c4a7e8c
https://doi.org/10.1101/2021.09.13.460183
https://doi.org/10.1101/2021.09.13.460183
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Chronic otitis media (OM) is the most common cause of hearing loss worldwide, yet the underlying genetics and molecular pathology are poorly understood. The mouse mutant Jeff is a single gene mouse model for OM identified from a deafness screen as pa
Autor:
Wolf Reik, Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, Fátima Santos, Mélanie A. Eckersley-Maslin, Oana Kubinyecz, Oliver Stegle
Zygotic genome activation (ZGA) is a crucial developmental milestone that remains poorly understood. This first essential transcriptional event in embryonic development coincides with extensive epigenetic reprogramming processes and is orchestrated,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737c50dcc792b18ae8b16f06505c4168
https://doi.org/10.1101/741371
https://doi.org/10.1101/741371
Autor:
Fátima Santos, Oana Kubinyecz, Mélanie A. Eckersley-Maslin, Celia Alda-Catalinas, Wolf Reik, Irene Hernando-Herraez, Danila Bredikhin, Oliver Stegle
Publikováno v:
Cell Systems
Summary Zygotic genome activation (ZGA) is an essential transcriptional event in embryonic development that coincides with extensive epigenetic reprogramming. Complex manipulation techniques and maternal stores of proteins preclude large-scale functi
Publikováno v:
Frontiers in Genetics
Chronic otitis media (OM) is the most common cause of hearing loss worldwide, yet the underlying genetics and molecular pathology are poorly understood. The mouse mutant Jeff is a single gene mouse model for OM identified from a deafness screen as pa