Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Oakleigh M. Folkes"'
Autor:
Bretton P. Nabit, Lutz Hein, Ralf Gilsbach, Aakash Basu, Oakleigh M. Folkes, Danny G. Winder, Rafael E. Perez, Sachin Patel, Nicholas A. Harris
Publikováno v:
Neuropsychopharmacology. 45:1473-1481
The α2a-adrenergic receptor (α2a-AR) agonist guanfacine has been investigated as a potential treatment for substance use disorders. While decreasing stress-induced reinstatement of cocaine seeking in animal models and stress-induced craving in huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fb1bde69811c3d5818e60a7265bfc35
https://doi.org/10.1038/s41386-020-0641-z
https://doi.org/10.1038/s41386-020-0641-z
Autor:
Rafael E, Perez, Aakash, Basu, Bretton P, Nabit, Nicholas A, Harris, Oakleigh M, Folkes, Sachin, Patel, Ralf, Gilsbach, Lutz, Hein, Danny G, Winder
Publikováno v:
Neuropsychopharmacology
The α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::810b19ad9f941c7a97e0c39658577d8a
https://pubmed.ncbi.nlm.nih.gov/32152411
https://pubmed.ncbi.nlm.nih.gov/32152411
Autor:
Oakleigh M. Folkes, Danny G. Winder, Ken Mackie, Shana M. Augustin, Walker P. Parrish, Samuel W. Centanni, Jason R. Stephenson, Roger J. Colbran, David M. Lovinger, Hala K. Haddad, Sachin Patel, Brian C. Shonesy, Keeley L. Spiess, Rebecca J. Bluett, Rita Báldi, Christian R. Marks
Publikováno v:
Biological Psychiatry. 84:304-315
Background Endocannabinoid signaling plays an important role in regulating synaptic transmission in the striatum, a brain region implicated as a central node of dysfunction in autism spectrum disorder. Deficits in signaling mediated by the endocannab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4bdda1437b5ca7db890d38e5a9f033
https://doi.org/10.1016/j.biopsych.2017.11.036
https://doi.org/10.1016/j.biopsych.2017.11.036
Autor:
Carrie A. Grueter, Maya P. Misra, Rita Báldi, Nolan D. Hartley, Brad A. Grueter, Oakleigh M. Folkes, Sachin Patel, Megan Altemus, David J. Marcus, Brandon D. Turner, Jordan J. Baechle, Veronika Kondev, Jade K. Ayers
Publikováno v:
J Clin Invest
Deficits in social interaction (SI) are a core symptom of autism spectrum disorders (ASDs); however, treatments for social deficits are notably lacking. Elucidating brain circuits and neuromodulatory signaling systems that regulate sociability could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e1c735e31e3d2aa48adda0143be31c
https://pubmed.ncbi.nlm.nih.gov/31874107
https://pubmed.ncbi.nlm.nih.gov/31874107
Autor:
Libin Xu, Zeljka Korade, Oakleigh M. Folkes, Fiona E. Harrison, Refayat Ahsen, Sarah E. Hart, Ned A. Porter, Karoly Mirnics
Publikováno v:
Biological Psychiatry. 75:215-222
Background Smith-Lemli-Opitz syndrome (SLOS) is an inborn error of cholesterol biosynthesis characterized by diminished cholesterol and increased 7-dehydrocholesterol (7-DHC) levels. 7-Dehydrocholesterol is highly reactive, giving rise to biologicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df1a755862554c39c9402b91f004ad6
https://doi.org/10.1016/j.biopsych.2013.06.013
https://doi.org/10.1016/j.biopsych.2013.06.013
Publikováno v:
Pharmacology Biochemistry and Behavior. 106:101-108
Smith–Lemli–Opitz syndrome (SLOS) is a developmental disorder resulting from mutations to the Dhcr7 gene, which is required for cholesterol synthesis. Patients with SLOS typically exhibit a number of severe behavioral deficits and many are diagno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328649b8f2575cb851d58a3b2852ba74
https://doi.org/10.1016/j.pbb.2013.03.007
https://doi.org/10.1016/j.pbb.2013.03.007
Autor:
Hussain Jinnah, Sarah B. Robinson, Daniel P. Bermingham, Oakleigh M. Folkes, Randy D. Blakely, Greg J. Salimando, J. Andrew Hardaway, Chelsea L. Snarrenberg
Modulation of neurotransmission by the catecholamine dopamine (DA) is conserved across phylogeny. In the nematode Caenorhabditis elegans, excess DA signaling triggers Swimming-Induced Paralysis (Swip), a phenotype first described in animals with loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ffd2b9b654566d73e0100da2634fc6
https://europepmc.org/articles/PMC4969213/
https://europepmc.org/articles/PMC4969213/
