Zobrazeno 1 - 10
of 1 806
pro vyhledávání: '"Oakhill A"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
STK11 (serine-threonine kinase 11), also known as LKB1 (liver kinase B1) is a highly conserved master kinase that regulates cellular metabolism and polarity through a complex signaling network involving AMPK and 12 other AMPK-related kinases. Germlin
Externí odkaz:
https://doaj.org/article/2d9eb9223df44d2c99aa1717a5575061
Autor:
Marina Katerelos, Kurt Gleich, Geoff Harley, Kim Loh, Jonathan S. Oakhill, Bruce E. Kemp, David P. de Souza, Vinod K. Narayana, Melinda T. Coughlan, Adrienne Laskowski, Naomi X.Y. Ling, Lisa Murray-Segal, Robert Brink, Mardiana Lee, David A. Power, Peter F. Mount
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116730- (2024)
Acute kidney injury (AKI) disrupts energy metabolism. Targeting metabolism through AMP-activated protein kinase (AMPK) may alleviate AKI. ATX-304, a pan-AMPK activator, was evaluated in C57Bl/6 mice and tubular epithelial cell (TEC) cultures. Mice re
Externí odkaz:
https://doaj.org/article/49bb1d8ce07747f89e0a801918a28713
Publikováno v:
In Molecular Metabolism December 2024 90
Autor:
Katerelos, Marina, Gleich, Kurt, Harley, Geoff, Loh, Kim, Oakhill, Jonathan S., Kemp, Bruce E., de Souza, David P., Narayana, Vinod K., Coughlan, Melinda T., Laskowski, Adrienne, Ling, Naomi X.Y., Murray-Segal, Lisa, Brink, Robert, Lee, Mardiana, Power, David A., Mount, Peter F.
Publikováno v:
In Biomedicine & Pharmacotherapy June 2024 175
Autor:
Rivka Gelman, Jillian Whelan, Sheree Spiteri, Danijela Duric, Winnie Oakhill, Samuel Cassar, Penelope Love
Publikováno v:
International Journal of Behavioral Nutrition and Physical Activity, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background Instilling healthy dietary habits and active play in early childhood is an important public health focus. Interventions supporting the establishment of nutrition and active play behaviours in the first years of life have shown pos
Externí odkaz:
https://doaj.org/article/005a46925d11442593659d7f79e9e1d8
Autor:
Negoita, Florentina, Addinsall, Alex B., Hellberg, Kristina, Bringas, Conchita Fraguas, Hafen, Paul S., Sermersheim, Tyler J., Agerholm, Marianne, Lewis, Christopher T.A., Ahwazi, Danial, Ling, Naomi X.Y., Larsen, Jeppe K., Deshmukh, Atul S., Hossain, Mohammad A., Oakhill, Jonathan S., Ochala, Julien, Brault, Jeffrey J., Sankar, Uma, Drewry, David H., Scott, John W., Witczak, Carol A., Sakamoto, Kei
Publikováno v:
In Molecular Metabolism September 2023 75
Autor:
Heena Doshi, Katrin Spengler, Amod Godbole, Yi Sing Gee, Jonathan Baell, Jonathan S. Oakhill, Andreas Henke, Regine Heller
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Herpes simplex virus type 1 (HSV-1) is a widespread contagious pathogen, mostly causing mild symptoms on the mucosal entry side. However, systemic distribution, in particular upon reactivation of the virus in immunocompromised patients, may
Externí odkaz:
https://doaj.org/article/9cbb143a3735452499080643bf1bfa2d
Autor:
Florentina Negoita, Alex B. Addinsall, Kristina Hellberg, Conchita Fraguas Bringas, Paul S. Hafen, Tyler J. Sermersheim, Marianne Agerholm, Christopher T.A. Lewis, Danial Ahwazi, Naomi X.Y. Ling, Jeppe K. Larsen, Atul S. Deshmukh, Mohammad A. Hossain, Jonathan S. Oakhill, Julien Ochala, Jeffrey J. Brault, Uma Sankar, David H. Drewry, John W. Scott, Carol A. Witczak, Kei Sakamoto
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101761- (2023)
Objective: The AMP-activated protein kinase (AMPK) gets activated in response to energetic stress such as contractions and plays a vital role in regulating various metabolic processes such as insulin-independent glucose uptake in skeletal muscle. The
Externí odkaz:
https://doaj.org/article/9d5e5d0c7c7842288457d872e1ccedfc
Autor:
Ayeshah A. Rosdah, Belinda M. Abbott, Christopher G. Langendorf, Yali Deng, Jia Q. Truong, Helen M. M. Waddell, Naomi X. Y. Ling, William J. Smiles, Lea M. D. Delbridge, Guei-Sheung Liu, Jonathan S. Oakhill, Shiang Y. Lim, Jessica K. Holien
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Mitochondrial dynamin-related protein 1 (Drp1) is a large GTPase regulator of mitochondrial dynamics and is known to play an important role in numerous pathophysiological processes. Despite being the most widely used Drp1 inhibitor, the spec
Externí odkaz:
https://doaj.org/article/81d43f7ed5984ba3b02b0644c4d9b73f
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