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Resolution of cast nephropathy following free light chain removal by haemodialysis in a patient with multiple myeloma: a case report

Autor: Basnayake Kolitha, Hutchison Colin, Kamel Dia, Sheaff Michael, Ashman Neil, Cook Mark, Oakervee Heather, Bradwell Arthur, Cockwell Paul

Publikováno v: Journal of Medical Case Reports, Vol 2, Iss 1, p 380 (2008)

Abstract Introduction Acute renal failure in multiple myeloma is most frequently caused by cast nephropathy, when excess monoclonal free light chains co-precipitate with Tamm-Horsfall protein in the distal nephron, causing tubular obstruction. The na

Externí odkaz: https://doaj.org/article/585ea76fb4164d82871d536c5ba2fda2

Randomized phase III study (ADMYRE) of plitidepsin in combination with dexamethasone vs. dexamethasone alone in patients with relapsed/refractory multiple myeloma.

Autor: Spicka I; Department of Medicine, Faculty of Medicine, Charles University and General Hospital, Prague, Czech Republic., Ocio EM; Department of Hematology, University Hospital Marqués de Valdecilla/IDIVAL, University of Cantabria, Santander, Spain., Oakervee HE; Department of Haemato-Oncology, St Bartholomew's Cancer Centre, Barts Health NHS Trust, London, UK., Greil R; 3rd Medical Department, Paracelsus Medical University Salzburg, Salzburg Cancer Research Institute, Cancer Cluster Salzburg, Salzburg, Austria., Banh RH; Department of Clinical Haematology, Mater Health Services, Brisbane, Australia., Huang SY; Department of Medicine, National Taiwan University Hospital, Taipei, Taiwan., D'Rozario JM; Department of Hematology, Canberra Hospital and Health Service, Canberra, Australia., Dimopoulos MA; Department of Clinical Therapeutics, Alexandra General Hospital, Athens, Greece., Martínez S; Clinical R&D, Pharma Mar, Colmenar Viejo, Madrid, Spain., Extremera S; Clinical R&D, Pharma Mar, Colmenar Viejo, Madrid, Spain., Kahatt C; Clinical R&D, Pharma Mar, Colmenar Viejo, Madrid, Spain., Alfaro V; Clinical R&D, Pharma Mar, Colmenar Viejo, Madrid, Spain., Carella AM; Department of Hematology, IRCCS Azienda Ospedaliera Universitaria San Martino, IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy., Meuleman N; Department of Hematology, Institut Jules Bordet (ULB), Brussels, Belgium., Hájek R; Department of Hematology-Oncology, Faculty of Medicine, University Hospital Ostrava, Ostrava, Czech Republic., Symeonidis A; Hematology Division, Department of Internal Medicine, University of Patras Medical School, Patras, Greece., Min CK; Department of Blood and Marrow Transplantation, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea., Cannell P; Department of Medicine, Royal Perth Hospital, Perth, Australia., Ludwig H; Wilhelminen Cancer Research Institute, Department of Medicine, Center for Oncology, Hematology and Palliative Care, Wilhelminen Hospital, Vienna, Austria., Sonneveld P; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Mateos MV; Department of Hematology, University Hospital of Salamanca/IBSAL, Salamanca, Spain. mvmateos@usal.es.; Departamento de Hematología, Hospital Universitario de Salamanca, Paseo de San Vicente, 58-182, 37007, Salamanca, Spain. mvmateos@usal.es.

Publikováno v: Annals of hematology [Ann Hematol] 2019 Sep; Vol. 98 (9), pp. 2139-2150. Date of Electronic Publication: 2019 Jun 25.

Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7 inhibitor and clinical candidate, DTP3.

Autor: Tornatore L; CCSI, Department of Medicine, Imperial College London, London, UK., Capece D; CCSI, Department of Medicine, Imperial College London, London, UK., D'Andrea D; CCSI, Department of Medicine, Imperial College London, London, UK., Begalli F; CCSI, Department of Medicine, Imperial College London, London, UK., Verzella D; CCSI, Department of Medicine, Imperial College London, London, UK., Bennett J; CCSI, Department of Medicine, Imperial College London, London, UK., Acton G; Cancer Research UK Centre for Drug Development, London, UK., Campbell EA; C&C Management Consulting Ltd, Exmouth, UK., Kelly J; Alpha Preclinical Consultancy, Halifax, UK., Tarbit M; Independent Consultant, Royston, UK., Adams N; In2Phase Ltd, Welwyn Garden City, UK., Bannoo S; CCSI, Department of Medicine, Imperial College London, London, UK., Leonardi A; Department of Molecular Medicine, University of Naples Federico II, Naples, Italy., Sandomenico A; IBB-CNR and CIRPeB, 'Federico II' University of Naples, Naples, Italy., Raimondo D; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Ruvo M; IBB-CNR and CIRPeB, 'Federico II' University of Naples, Naples, Italy., Chambery A; DiSTABiF, University of Campania 'Luigi Vanvitelli', Caserta, Italy., Oblak M; West Middlesex University Hospital, Isleworth, Greater London, UK., Al-Obaidi MJ; Haematology Department, Chelsea and Westminster Hospital, London, UK., Kaczmarski RS; London Haematology Limited, London, UK., Gabriel I; Haematology Department, Chelsea and Westminster Hospital, London, UK., Oakervee HE; Barts Cancer Centre, St Bartholomew's Hospital London, London, UK., Kaiser MF; Division of Molecular Pathology, The Institute of Cancer Research, London, UK., Wechalekar A; Royal Free London NHS Foundation Trust, London, UK., Benjamin R; Department of Haematology, King's College Hospital, London, UK., Apperley JF; Centre for Haematology, Imperial College, London, UK., Auner HW; Centre for Haematology, Imperial College, London, UK.; Cancer Cell Protein Metabolism, Department of Medicine, Imperial College London, London, UK., Franzoso G; CCSI, Department of Medicine, Imperial College London, London, UK.

Publikováno v: Toxicology reports [Toxicol Rep] 2019 Apr 19; Vol. 6, pp. 369-379. Date of Electronic Publication: 2019 Apr 19 (Print Publication: 2019).

Bile acid malabsorption in patients with graft-versus-host disease of the gastrointestinal tract.

Autor: Joshi NM, Hassan S, Jasani P, Dixon S, Cavenagh JD, Oakervee HE, Smith M, Agrawal SA, Auer R, de Vos J, Langmead L, Rampton DS, Gribben JG, Taussig DC

Publikováno v: British journal of haematology [Br J Haematol] 2012 May; Vol. 157 (3), pp. 403-7. Date of Electronic Publication: 2012 Jan 09.