Zobrazeno 1 - 10
of 100
pro vyhledávání: '"OZAIR ALAM"'
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 11, Iss , Pp 100167- (2024)
Diabetes mellitus (Type 2) is a major world health problem spreading speedily throughout the world. It is a chronic illness that necessitates long-term therapy and care. Therefore, the therapy to treat and manage the disease should not only be safe a
Externí odkaz:
https://doaj.org/article/a1424d41826f4a3abb27ad52a7468801
Autor:
Mohd Imran, Qasim M. Alhadidi, Shah Alam Khan, Hamdy Khamees Thabet, Ozair Alam, Faiyaz Shakeel, Ziyaur Rahman, Muhammad Wahab Amjad
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/33da9dcfe7e04d09be6c49eb030bcce7
Autor:
Vishal Mathur, Ozair Alam, Nadeem Siddiqui, Mukund Jha, Ajay Manaithiya, Sandhya Bawa, Naveen Sharma, Sultan Alshehri, Prawez Alam, Faiyaz Shakeel
Publikováno v:
Molecules, Vol 28, Iss 15, p 5860 (2023)
This article sheds light on the various scaffolds that can be used in the designing and development of novel synthetic compounds to create DPP-4 inhibitors for the treatment of type 2 diabetes mellitus (T2DM). This review highlights a variety of scaf
Externí odkaz:
https://doaj.org/article/f105df4c4791492d8df892a4474ef50a
Autor:
Bharti Mangla, Sarwar Beg, Ozair Alam, Waquar Ahsan, Anzarul Haque, Kuldeep Singh Patel, Waleed Hassan Almalki, Majed Alrobaian, Kanchan Kohli
Publikováno v:
Arabian Journal of Chemistry, Vol 13, Iss 11, Pp 7909-7920 (2020)
Tamoxifen (TAM) and Sulphoraphane (SFN) are well-known anti-estrogen drugs used for the treatment of breast cancer. Due to their synergistic therapeutic potential, their combination is preferred as it helps to minimize the drug-related toxicities and
Externí odkaz:
https://doaj.org/article/53a75c5de76944ba88c53aaca9d744f3
Autor:
Kahksha, Ozair Alam, Lamya Ahmed Al-Keridis, Jalaluddin Khan, Sameena Naaz, Afshar Alam, Syed Amir Ashraf, Nawaf Alshammari, Mohd Adnan, Md Amjad Beg
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 3, p 126 (2023)
Despite the existence of modern antidiabetic medications, diabetes still affects millions of individuals worldwide, with a high death and disability rate. There has been a concerted search for alternative natural medicinal agents; luteolin (LUT), a p
Externí odkaz:
https://doaj.org/article/deadcd53c8d64018828b94bb806a26be
Autor:
Md. Jahangir Alam, Ozair Alam, Mohd. Javed Naim, Farah Nawaz, Ajay Manaithiya, Mohd Imran, Hamdy Khamees Thabet, Sultan Alshehri, Mohammed M. Ghoneim, Prawez Alam, Faiyaz Shakeel
Publikováno v:
Molecules, Vol 27, Iss 24, p 8708 (2022)
Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti-inflammatory, anti-microbial, anti-anxiety, anticancer, analgesic, antipy
Externí odkaz:
https://doaj.org/article/6c78b83607334a1291573b824dfbe948
Autor:
Garima Verma, Mohemmed Faraz Khan, Wasim Akhtar, Mohammad Mumtaz Alam, Mymoona Akhter, Ozair Alam, Syed Misbahul Hasan, Mohammad Shaquiquzzaman
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 4815-4839 (2019)
Pharmacophore modeling, molecular docking and in silico ADME prediction have been performed for quinazoline based EGFR inhibitors. This study has been carried out to determine the binding mode and drug likeliness nature of compounds. A five point mod
Externí odkaz:
https://doaj.org/article/83178623bd9140449a1b276965888699
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Epilepsy is a complex neurological disorder, characterized by frequent electrical activity in brain regions. Inflammation and apoptosis cascade activation are serious neurological sequelae during seizures. Fisetin (3, 3′,4′,7-tetrahydroxyflavone)
Externí odkaz:
https://doaj.org/article/520c697fbc704bd59bd39fd94dcad24e
Autor:
Mohd Imran, Shah Alam Khan, Abida, Mohammed Kanan Alshammari, Saif M. Alkhaldi, Fayez Nafea Alshammari, Mehnaz Kamal, Ozair Alam, Syed Mohammed Basheeruddin Asdaq, A. Khuzaim Alzahrani, Shahamah Jomah
Publikováno v:
Molecules, Vol 27, Iss 9, p 2750 (2022)
COVID-19 has had an impact on human quality of life and economics. Scientists have been identifying remedies for its prevention and treatment from all possible sources, including plants. Nigella sativa L. (NS) is an important medicinal plant of Islam
Externí odkaz:
https://doaj.org/article/075edb13891d4f88bb8a09ff9910c8a6
Autor:
Md. Jahangir Alam, Ozair Alam, Ahmad Perwez, Moshahid Alam Rizvi, Mohd Javed Naim, Vegi G. M. Naidu, Mohd Imran, Mohammed M. Ghoneim, Sultan Alshehri, Faiyaz Shakeel
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 280 (2022)
Some (E)-3-(3-(4-(benzyloxy)phenyl)-1-phenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-one conjugates 5a–r were designed; synthesized; characterized by 1H, 13C NMR, and ESI-MS; and evaluated for tubulin polymerization inhibitory activity and in vitro cy
Externí odkaz:
https://doaj.org/article/2f2a169b12e640f0a659a9341b0d9fdc