Long-term orally exposure of dioxins affects antigen-specific antibody production in mice

Autor: Hideki Kakutani, Tomohiro Yuzuriha, Teruyuki Nakao, Souichi Ohta

Publikováno v: Toxicology Reports, Vol 9, Iss , Pp 53-57 (2022)

Dioxins are persistent environmental toxins that are still present in the food supply despite strong efforts to minimize exposure. Dioxins ingested by humans accumulate in fat and are excreted very slowly, so their long-term effects at low concentrat

Externí odkaz: https://doaj.org/article/c8494ec1f4ce4d1b98252184874cd9ab

Long-term orally exposure of dioxins affects antigen-specific antibody production in mice

Autor: Hideki Kakutani, Tomohiro Yuzuriha, Teruyuki Nakao, Souichi Ohta

Publikováno v: Toxicology Reports
Toxicology Reports, Vol 9, Iss, Pp 53-57 (2022)

Graphical abstract
Highlights • Antigen-specific (OVA) antibody production in the serum increased dose-dependently by TCDD concentrations below 500 ng/kg after long-term (10 weeks) exposure. • Similar increases were seen in fecal and vaginal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16725fa7ff93dc4a564d2d4d6b191da
https://pubmed.ncbi.nlm.nih.gov/35004181

Long-term orally exposure of dioxins affects antigen-specific antibody production in mice.

Autor: Kakutani H; Laboratory of Disease Prevention, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan., Yuzuriha T; Laboratory of Disease Prevention, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan., Nakao T; Laboratory of Disease Prevention, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan., Ohta S; Laboratory of Disease Prevention, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan.

Publikováno v: Toxicology reports [Toxicol Rep] 2021 Dec 20; Vol. 9, pp. 53-57. Date of Electronic Publication: 2021 Dec 20 (Print Publication: 2022).