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Akademický článek

Anti-gastric cancer effect of a novel small molecule inhibitor 1-3-51 targeting FOXM1 in vitro

Autor: GAO Mengyuan, GU Jing, LUO Ya, TANG Qingyun, ZHANG Shengwei, HU Changjiang, OUYANG Qin, YANG Shiming

Publikováno v: Di-san junyi daxue xuebao, Vol 43, Iss 9, Pp 798-805 (2021)

Objective To investigate the role of a novel small molecule inhibitor 1-3-51 in the regulation of FOXM1 expression and its anticancer effect in gastric cancer. Methods CCK-8 assay was employed to measure the IC50 values in gastric cancer BGC823 and M

Externí odkaz: https://doaj.org/article/0a534887bf8947529842302f6bb51a07

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Akademický článek

Metformin enhances erectile function in rats with aging-induced erectile dysfunction by activating AMPK/mTOR pathway-regulated autophagy in corpus cavernosum

Autor: DING Fan, LI Hongwei, OUYANG Qin, WU Xiaojun

Publikováno v: Di-san junyi daxue xuebao, Vol 42, Iss 11, Pp 1109-1115 (2020)

Objective To investigate the effect of metformin on erectile function and its regulation on cavernous fibrosis and autophagy in aged rats, and explore the underlying mechanism. Methods Forty healthy 2-month-old male SD rats were randomly divided into

Externí odkaz: https://doaj.org/article/a5e2d0b935834624a50d8c06d61c794b

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Akademický článek

Recurrent BMP4 variants in exon 4 cause non-HFE-associated hemochromatosis via the BMP/SMAD signaling pathway.

Autor: Ouyang, Qin¹ (AUTHOR), Li, Yanmeng¹ (AUTHOR), Xu, Anjian¹ (AUTHOR), Zhang, Ning² (AUTHOR), Chen, Sisi¹ (AUTHOR), Zhou, Donghu¹ (AUTHOR), Zhang, Bei¹ (AUTHOR), Ou, Xiaojuan² (AUTHOR), Jia, Jidong² (AUTHOR), Huang, Jian¹ (AUTHOR) huangj1966@hotmail.com, Zhang, Wei² (AUTHOR) zhangwei2020@ccmu.edu.cn

Publikováno v: Orphanet Journal of Rare Diseases. 11/19/2024, Vol. 19 Issue 1, p1-9. 9p.

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