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Speaker abstracts 2001.
Background Objectives To compare the steady-state AUC(0–24 h) of rofecoxib, dosed @ approx 0.32 mg/kg/day in children aged 2 to 17 years vs. adult historical controls who received one 25-mg tablet daily (mean weight of 77.7 kg, corresponding to ~0.
Rheumatoid arthritis (RA) is the most common and most severe form of inflammatory arthritis. The pathogenesis of RA has been the subject of intense research for several decades. The prevailing hypotheses have changed over the years, and have attempte