Zobrazeno 1 - 10
of 237
pro vyhledávání: '"OSAMU TANABE"'
Autor:
Junichi Sugawara, Mami Ishikuro, Taku Obara, Tomomi Onuma, Keiko Murakami, Masahiro Kikuya, Fumihiko Ueno, Aoi Noda, Satoshi Mizuno, Tomoko Kobayashi, Yohei Hamanaka, Kichiya Suzuki, Eiichi Kodama, Naho Tsuchiya, Akira Uruno, Yoichi Suzuki, Osamu Tanabe, Hideyasu Kiyomoto, Akito Tsuboi, Atsushi Shimizu, Seizo Koshiba, Naoko Minegishi, Soichi Ogishima, Gen Tamiya, Hirohito Metoki, Atsushi Hozawa, Nobuo Fuse, Kengo Kinoshita, Shigeo Kure, Nobuo Yaegashi, Shinichi Kuriyama, Masayuki Yamamoto
Publikováno v:
Journal of Epidemiology, Vol 32, Iss 2, Pp 69-79 (2022)
Background: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study was launched in 2013 to evaluate the complex interactions of genetic and environmental factors in multifactorial diseases. The present study describes the materna
Externí odkaz:
https://doaj.org/article/29f115b3570c4e88a64d6eda3975ac8b
Autor:
Takafumi Yamauchi, Daisuke Ochi, Naomi Matsukawa, Daisuke Saigusa, Mami Ishikuro, Taku Obara, Yoshiki Tsunemoto, Satsuki Kumatani, Riu Yamashita, Osamu Tanabe, Naoko Minegishi, Seizo Koshiba, Hirohito Metoki, Shinichi Kuriyama, Nobuo Yaegashi, Masayuki Yamamoto, Masao Nagasaki, Satoshi Hiyama, Junichi Sugawara
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The elucidation of dynamic metabolomic changes during gestation is particularly important for the development of methods to evaluate pregnancy status or achieve earlier detection of pregnancy-related complications. Some studies have construc
Externí odkaz:
https://doaj.org/article/29fb6bbfa97f4ccc98f20c973417a67f
Autor:
Atsushi Hozawa, Kozo Tanno, Naoki Nakaya, Tomohiro Nakamura, Naho Tsuchiya, Takumi Hirata, Akira Narita, Mana Kogure, Kotaro Nochioka, Ryohei Sasaki, Nobuyuki Takanashi, Kotaro Otsuka, Kiyomi Sakata, Shinichi Kuriyama, Masahiro Kikuya, Osamu Tanabe, Junichi Sugawara, Kichiya Suzuki, Yoichi Suzuki, Eiichi N Kodama, Nobuo Fuse, Hideyasu Kiyomoto, Hiroaki Tomita, Akira Uruno, Yohei Hamanaka, Hirohito Metoki, Mami Ishikuro, Taku Obara, Tomoko Kobayashi, Kazuyuki Kitatani, Takako Takai-Igarashi, Soichi Ogishima, Mamoru Satoh, Hideki Ohmomo, Akito Tsuboi, Shinichi Egawa, Tadashi Ishii, Kiyoshi Ito, Sadayoshi Ito, Yasuyuki Taki, Naoko Minegishi, Naoto Ishii, Masao Nagasaki, Kazuhiko Igarashi, Seizo Koshiba, Ritsuko Shimizu, Gen Tamiya, Keiko Nakayama, Hozumi Motohashi, Jun Yasuda, Atsushi Shimizu, Tsuyoshi Hachiya, Yuh Shiwa, Teiji Tominaga, Hiroshi Tanaka, Kotaro Oyama, Ryoichi Tanaka, Hiroshi Kawame, Akimune Fukushima, Yasushi Ishigaki, Tomoharu Tokutomi, Noriko Osumi, Tadao Kobayashi, Fuji Nagami, Hiroaki Hashizume, Tomohiko Arai, Yoshio Kawaguchi, Shinichi Higuchi, Masaki Sakaida, Ryujin Endo, Satoshi Nishizuka, Ichiro Tsuji, Jiro Hitomi, Motoyuki Nakamura, Kuniaki Ogasawara, Nobuo Yaegashi, Kengo Kinoshita, Shigeo Kure, Akio Sakai, Seiichiro Kobayashi, Kenji Sobue, Makoto Sasaki, Masayuki Yamamoto
Publikováno v:
Journal of Epidemiology, Vol 31, Iss 1, Pp 65-76 (2021)
Background: We established a community-based cohort study to assess the long-term impact of the Great East Japan Earthquake on disaster victims and gene-environment interactions on the incidence of major diseases, such as cancer and cardiovascular di
Externí odkaz:
https://doaj.org/article/64f92cd82beb4bfabc4ed85922f051b4
Oral Microbiome Analysis in Prospective Genome Cohort Studies of the Tohoku Medical Megabank Project
Autor:
Sakae Saito, Yuichi Aoki, Toru Tamahara, Maki Goto, Hiroyuki Matsui, Junko Kawashima, Inaho Danjoh, Atsushi Hozawa, Shinichi Kuriyama, Yoichi Suzuki, Nobuo Fuse, Shigeo Kure, Riu Yamashita, Osamu Tanabe, Naoko Minegishi, Kengo Kinoshita, Akito Tsuboi, Ritsuko Shimizu, Masayuki Yamamoto
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
A baseline oral microbiome study of the Tohoku Medical Megabank Organization (TMM) was planned to characterize the profile of the oral microbiome in the Japanese population. The study also aimed to clarify risk factors for multifactorial diseases by
Externí odkaz:
https://doaj.org/article/9a24a0a4c6154f059523791ac9c6e3b9
Autor:
Jinhua Liu, Yapu Li, Jingyuan Tong, Jie Gao, Qing Guo, Lingling Zhang, Bingrui Wang, Hui Zhao, Hongtao Wang, Erlie Jiang, Ryo Kurita, Yukio Nakamura, Osamu Tanabe, James Douglas Engel, Emery H. Bresnick, Jiaxi Zhou, Lihong Shi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
LncRNAs modulate diverse physiological cellular processes, however, their involvement in heme-dependent processes are not yet clear. Here the authors reveal the role of lncRNA UCA1 in erythroid cell development.
Externí odkaz:
https://doaj.org/article/b77cd360ed4e47e48a6cfe13667efaf8
Autor:
Jun Yasuda, Fumiki Katsuoka, Inaho Danjoh, Yosuke Kawai, Kaname Kojima, Masao Nagasaki, Sakae Saito, Yumi Yamaguchi-Kabata, Shu Tadaka, Ikuko N. Motoike, Kazuki Kumada, Mika Sakurai-Yageta, Osamu Tanabe, Nobuo Fuse, Gen Tamiya, Koichiro Higasa, Fumihiko Matsuda, Nobufumi Yasuda, Motoki Iwasaki, Makoto Sasaki, Atsushi Shimizu, Kengo Kinoshita, Masayuki Yamamoto
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Genotype imputation from single-nucleotide polymorphism (SNP) genotype data using a haplotype reference panel consisting of thousands of unrelated individuals from populations of interest can help to identify strongly associated v
Externí odkaz:
https://doaj.org/article/cecc524793a54decb8d6af85a3f7ab86
Autor:
Yukiko Matsuda, Arikuni Uchimura, Yasunari Satoh, Naohiro Kato, Masaaki Toshishige, Junko Kajimura, Kanya Hamasaki, Kengo Yoshida, Tomonori Hayashi, Asao Noda, Osamu Tanabe
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Spectra and frequencies of spontaneous and X-ray-induced somatic mutations were revealed with mouse long-term hematopoietic stem cells (LT-HSCs) by whole-genome sequencing of clonal cell populations propagated in vitro from single isolated LT-HSCs. S
Autor:
Mami Ishikuro, Yoichi Suzuki, Masahiro Kikuya, Shinichi Kuriyama, Naho Tsuchiya, Hirohito Metoki, Aoi Noda, Tomomi Onuma, Naoko Minegishi, Atsushi Hozawa, Keiko Murakami, Atsushi Shimizu, Osamu Tanabe, Taku Obara, Akito Tsuboi, Masayuki Yamamoto, Soichi Ogishima, Tomoko Kobayashi, Satoshi Mizuno, Kengo Kinoshita, Akira Uruno, Eiichi Kodama, Junichi Sugawara, Nobuo Yaegashi, Yohei Hamanaka, Fumihiko Ueno, Gen Tamiya, Nobuo Fuse, Seizo Koshiba, Shigeo Kure, Hideyasu Kiyomoto, Kichiya Suzuki
Publikováno v:
Journal of Epidemiology, Vol 32, Iss 2, Pp 69-79 (2022)
Journal of Epidemiology
Journal of Epidemiology
Background The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study was launched in 2013 to evaluate the complex interactions of genetic and environmental factors in multifactorial diseases. The present study describes the maternal
Autor:
Daisuke Saigusa, Yasunobu Okamura, Ikuko N Motoike, Yasutake Katoh, Yasuhiro Kurosawa, Reina Saijyo, Seizo Koshiba, Jun Yasuda, Hozumi Motohashi, Junichi Sugawara, Osamu Tanabe, Kengo Kinoshita, Masayuki Yamamoto
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160555 (2016)
Metabolomics is a promising avenue for biomarker discovery. Although the quality of metabolomic analyses, especially global metabolomics (G-Met) using mass spectrometry (MS), largely depends on the instrumentation, potential bottlenecks still exist a
Externí odkaz:
https://doaj.org/article/45a7930ed3424a09ae296dd6fa9079cd
Autor:
Satoshi Makino, Kozo Tanno, Hiroshi Okuda, Gen Tamiya, Sadayoshi Ito, Atsushi Hozawa, Masayuki Yamamoto, Junichi Sugawara, Michiaki Abe, Makoto Sasaki, Tadashi Ishii, Osamu Tanabe, Kota Ishizawa, Koji Okamoto
Publikováno v:
Clinical and Experimental Nephrology
Background Urinary albumin excretion (UAE) is a risk factor for cardiovascular diseases, metabolic syndrome, chronic kidney disease, etc. Only a few genome-wide association studies (GWAS) for UAE have been conducted in the European population, but no