Genome-wide association study identifies CAMKID variants involved in blood pressure response to losartan: the SOPHIA study

Autor: FRAU F, ZANINELLO R, SALVI E, ORTU MF, BRAGA D, VELAYUTHAM D, ARGIOLAS G, FRESU G, TROFFA C, BULLA E, BULLA P, PITZOI S, PIRAS DA, GLORIOSO V, CHITTANI M, BERNINI G, BARDINI M, FALLO F, MALATINO L, STANCANELLI B, REGOLISTI G, FERRI C, DESIDERI G, SCIOLI GA, GALLETTI F, SCIACQUA A, PERTICONE F, DEGLI ESPOSTI E, STURANI A, SEMPLICINI A, VEGLIO F, MULATERO P, WILLIAMS TA, LANZANI C, HILTUNEN TP, KONTULA K, BOERWINKLE E, TURNER ST, BARLASSINA C, CUSI D, GLORIOSO N., MANUNTA , PAOLO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10495::4626721500abf135f533241800b07d16

Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.

Autor: Frau F, Citterio L, Ortu MF, Zaninello R, Frau, Francesca, Citterio, Lorena, Ortu, Maria Francesca, Zaninello, Roberta

Publikováno v: Hypertension (0194911X); Jan2013, Vol. 61 Issue 1, pe5-e5, 1p

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives

Autor: Simona Delli Carpini, Eric Boerwinkle, Erika Salvi, Gianluigi Condorelli, Marco Simonini, Lorena Citterio, Giovanni Fresu, Giuseppe Argiolas, Yan Gong, Sandosh Padmanabhan, Roberta Zaninello, Daniele Cusi, Anna F. Dominiczak, Daniela Antonella Piras, Maria Francesca Ortu, Dinesh Velayutham, Julie A. Johnson, Timo P. Hiltunen, Chiara Troffa, Rhonda M. Cooper-DeHoff, Chiara Lanzani, Bruno Trimarco, S. Pozzoli, Kati Donner, Daniele Braga, Nicola Glorioso, Martina Chittani, Kimmo Kontula, Cristina Barlassina, Arlene B. Chapman, Olle Melander, Francesca Frau, Paolo Manunta, Natalia V. Rivera, Valeria Glorioso, Stephen T. Turner

Publikováno v: Journal of hypertension. 33(6)

Thiazide diuretics have been recommended as a first-line antihypertensive treatment, although the choice of 'the right drug in the individual essential hypertensive patient' remains still empirical. Essential hypertension is a complex, polygenic dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5686dfd817d6ec06db4b8752e57711c
https://pubmed.ncbi.nlm.nih.gov/25923729

TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.

Autor: Chittani M; aDepartment of Health Sciences, University of Milan at San Paolo Hospital, and Filarete Foundation, Genomic and Bioinformatics Unit, Milan bHypertension and Related Disease Centre, AOU-University of Sassari, Sassari cUniversità Vita Salute San Raffaele, Nephrology and Dialysis and Hypertension Unit, San Raffaele Scientific Institute, Milan, Italy dDepartment of Medicine, University of Helsinki and Helsinki University Central Hospital eInstitute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland fDivision of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, Minnesota gHuman Genetics and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas hRenal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA iInstitute of Cardiovascular and Medical Sciences, College of Medicine Veterinary and Life Sciences, University of Glasgow, Glasgow, UK jDepartment of Clinical Sciences, Lund University, Malmö, Sweden kDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics, College of Pharmacy, University of Florida, Gainesville, Florida, USA lRespiratory Medicine Unit, Department of Medicine and CMM, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden mDepartment of Medical Biotechnologies and Translational Medicine, University of Milan, and Humanitas Clinical and Research Center, University of Milan, and National Research Council of Italy, Rozzano (MI) nDepartment of Clinical Medicine, Cardiovascular and Immunological Sciences, University of Naples 'Federico II', Naples, Italy *Martina Chittani and Roberta Zaninello contributed equally to the writing of this article., Zaninello R, Lanzani C, Frau F, Ortu MF, Salvi E, Fresu G, Citterio L, Braga D, Piras DA, Carpini SD, Velayutham D, Simonini M, Argiolas G, Pozzoli S, Troffa C, Glorioso V, Kontula KK, Hiltunen TP, Donner KM, Turner ST, Boerwinkle E, Chapman AB, Padmanabhan S, Dominiczak AF, Melander O, Johnson JA, Cooper-Dehoff RM, Gong Y, Rivera NV, Condorelli G, Trimarco B, Manunta P, Cusi D, Glorioso N, Barlassina C

Publikováno v: Journal of hypertension [J Hypertens] 2015 Jun; Vol. 33 (6), pp. 1301-9.

Sardinians genetic background explained by runs of homozygosity and genomic regions under positive selection.

Autor: Di Gaetano C; Department of Medical Sciences, University of Turin, Turin, Italy; HuGeF Human Genetics Foundation, Turin, Italy., Fiorito G; Department of Medical Sciences, University of Turin, Turin, Italy; HuGeF Human Genetics Foundation, Turin, Italy., Ortu MF; Hypertension and Related Diseases Center, AOU, University of Sassari, Sassari, Italy., Rosa F; HuGeF Human Genetics Foundation, Turin, Italy., Guarrera S; HuGeF Human Genetics Foundation, Turin, Italy., Pardini B; HuGeF Human Genetics Foundation, Turin, Italy., Cusi D; Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Viale Ortles 22/4, Milan, Italy., Frau F; Hypertension and Related Diseases Center, AOU, University of Sassari, Sassari, Italy; Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Viale Ortles 22/4, Milan, Italy., Barlassina C; Department of Health Sciences, University of Milan, Milan, Italy; Filarete Foundation, Genomic and Bioinformatics Unit, Viale Ortles 22/4, Milan, Italy., Troffa C; Hypertension and Related Diseases Center, AOU, University of Sassari, Sassari, Italy., Argiolas G; Hypertension and Related Diseases Center, AOU, University of Sassari, Sassari, Italy., Zaninello R; Hypertension and Related Diseases Center, AOU, University of Sassari, Sassari, Italy., Fresu G; Hypertension and Related Diseases Center, AOU, University of Sassari, Sassari, Italy., Glorioso N; Hypertension and Related Diseases Center, AOU, University of Sassari, Sassari, Italy., Piazza A; Department of Medical Sciences, University of Turin, Turin, Italy; HuGeF Human Genetics Foundation, Turin, Italy., Matullo G; Department of Medical Sciences, University of Turin, Turin, Italy; HuGeF Human Genetics Foundation, Turin, Italy.

Publikováno v: PloS one [PLoS One] 2014 Mar 20; Vol. 9 (3), pp. e91237. Date of Electronic Publication: 2014 Mar 20 (Print Publication: 2014).