Zobrazeno 1 - 10
of 30
pro vyhledávání: '"ORR, objective response rate"'
Autor:
Hao Wang, Lei Wang, Keyi Jia, Yu Liu, Sha Zhao, Wei Li, Caicun Zhou, Minlin Jiang, Bin Chen, Yayi He
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2983-2994 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2983-2994 (2021)
Genomic instability remains an enabling feature of cancer and promotes malignant transformation. Alterations of DNA damage response (DDR) pathways allow genomic instability, generate neoantigens, upregulate the expression of programmed death ligand 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe73202674a833d134ec811bcbf7332
https://doi.org/10.1016/j.apsb.2021.01.003
https://doi.org/10.1016/j.apsb.2021.01.003
Publikováno v:
Genes and Diseases, Vol 7, Iss 3, Pp 328-335 (2020)
Genes & Diseases
Genes & Diseases
Liver cancer, mostly hepatocellular carcinoma (HCC), is the second leading cause of cancer mortality globally. Most patients were diagnosed at an advanced stage, and systemic therapy is the standard of care. All the approved systemic therapies for HC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb19869f3bc3bfb3bae7b9eaa804f48c
https://doi.org/10.1016/j.gendis.2020.03.010
https://doi.org/10.1016/j.gendis.2020.03.010
Publikováno v:
Genes and Diseases, Vol 7, Iss 3, Pp 359-369 (2020)
Genes & Diseases
Genes & Diseases
Tumor recurrence rate after surgery or ablation of hepatocellular carcinoma (HCC) is as high as 70%. However, there are no widely accepted adjuvant therapies; therefore, no treatment has been recommended by guidelines from the American Association fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389b02e06369d54c5c7cd0a28e191866
http://www.sciencedirect.com/science/article/pii/S2352304220300325
http://www.sciencedirect.com/science/article/pii/S2352304220300325
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 12, Pp 101238-(2021)
Translational Oncology, Vol 14, Iss 12, Pp 101238-(2021)
Highlights • Sorafenib in combination with TACE can prolong survival in patients with hepatocellular carcinoma. • Compared with TACE + placebo / alone, the combination of TACE and sorafenib can significantly improve the efficacy and safety of hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b81951a380a5cfd57f90d14e20dcc2
https://pubmed.ncbi.nlm.nih.gov/34628285
https://pubmed.ncbi.nlm.nih.gov/34628285
Publikováno v:
JAAD Case Reports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43307cc7d79ed54f453d0e4c99fd2f4
https://doi.org/10.1016/j.jdcr.2019.06.034
https://doi.org/10.1016/j.jdcr.2019.06.034
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 5, Pp 100347-(2021)
JHEP Reports, Vol 3, Iss 5, Pp 100347-(2021)
Summary: Hepatocellular carcinoma (HCC) usually arises in the context of a chronically damaged liver. Liver functional estimation is of paramount importance in clinical decision making. The Child-Pugh score (CPS) can be used to categorise patients in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342c91c0dcda2d6413fae2c6753ee40b
https://pubmed.ncbi.nlm.nih.gov/34505035
https://pubmed.ncbi.nlm.nih.gov/34505035
Autor:
Takahiro Kogawa, Ako Hosono, Kenichi Harano, Ayumi Komuro, Yoichi Naito, Chihiro Kondoh, Kanako Mamishin, Shota Kusuhara, Chikako Funasaka, Toru Mukohara, Takehiro Nakao, Mashiro Okunaka, Toshikatsu Kawasaki, Yoko Fukasawa, Nobuaki Matsubara
Publikováno v:
The Breast : Official Journal of the European Society of Mastology
Breast, Vol 58, Iss, Pp 50-56 (2021)
Breast, Vol 58, Iss, Pp 50-56 (2021)
Background Visceral crisis in metastatic breast cancer (MBC) is defined as severe organ dysfunction requiring rapidly efficacious therapy. Although weekly paclitaxel plus bevacizumab (wPTX + BV) achieves a high response rate in human epidermal growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceeb2f8c28b19a71d25194b192d9cf8f
https://pubmed.ncbi.nlm.nih.gov/33901922
https://pubmed.ncbi.nlm.nih.gov/33901922
Autor:
Chuan Jin, Xinhua Du, Wei Zhang, Yuhuan Gao, Wei Li, Xiong Wang, Yongping Song, Wenqi Jiang, Yuankai Shi, Bo Peng, Hui Zhou, Zhengming Jin, Jianmin Yang, Yan Xiong, Wenbin Qian, Jianfeng Zhou, Lugui Qiu, Ming Hou, Xiuhua Sun, Liqun Zou, Hang Su
Publikováno v:
EBioMedicine, Vol 54, Iss, Pp-(2020)
EBioMedicine
EBioMedicine
Background: Blood-based biomarker such as circulating tumor DNA (ctDNA) has emerged as a promising tool for assessment of response to immunotherapy in solid tumors; But in hematological malignances, evidences are still lacking to support its clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa61d796c293143c03379523ac503116
http://www.sciencedirect.com/science/article/pii/S2352396420301067
http://www.sciencedirect.com/science/article/pii/S2352396420301067
Autor:
Diane Damotte, Marie Wislez, Anne-Catherine Piketty, Audrey Mansuet-Lupo, Sixtine De Percin, Pascaline Boudou-Rouquette, Clémentine Villeminey, François Goldwasser, Frédérique Giraud, Marco Alifano, Claire Gervais, J.-P. Durand, Anne Jouinot, Elizabeth Fabre, Jérôme Alexandre, Guillaume Ulmann, Jennifer Arrondeau, Nathalie Rassy
Publikováno v:
EBioMedicine, Vol 73, Iss, Pp 103630-(2021)
EBioMedicine
EBioMedicine
Background: Immune checkpoint inhibitors (ICI) are dramatically active in a minority of non-small cell lung cancer (NSCLC) patients. We studied here the relationship between patients's metabolism and outcome under ICI. Methods: Metastatic NSCLC patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0192c9b0373dca0ab25e7fa5bbd269f7
https://doi.org/10.1016/j.ebiom.2021.103630
https://doi.org/10.1016/j.ebiom.2021.103630
Publikováno v:
JHEP Reports
Summary Biliary tract cancers (BTCs) are aggressive epithelial malignancies that can arise at any point of the biliary tree. Albeit rare, their incidence and mortality rates have been rising steadily over the past 40 years, highlighting the need to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba037ba710b2d3cec7628aee5054cce
https://doi.org/10.1016/j.jhepr.2021.100226
https://doi.org/10.1016/j.jhepr.2021.100226