Zobrazeno 1 - 10
of 202
pro vyhledávání: '"ORAI3"'
Autor:
Duan Zhuo, Zhenchuan Lei, Lin Dong, Andrew Man Lok Chan, Jiacheng Lin, Liwen Jiang, Beibei Qiu, Xiaohua Jiang, Youhua Tan, Xiaoqiang Yao
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background One of major challenges in breast tumor therapy is the existence of breast cancer stem cells (BCSCs). BCSCs are a small subpopulation of tumor cells that exhibit characteristics of stem cells. BCSCs are responsible for progression
Externí odkaz:
https://doaj.org/article/63d4c9c768ef4ea1a736da1c5c8a38ac
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Cells, Vol 12, Iss 22, p 2613 (2023)
STIM1 has been identified as a new warm sensor, but the exact molecular mechanism remains unclear. In this study, a variety of mutants of STIM1, Orai1 and Orai3 were generated. The single–cell calcium imaging and confocal analysis were used to eval
Externí odkaz:
https://doaj.org/article/0663625934af408781998afdec2f3cb1
Autor:
Scott M Emrich, Ryan E Yoast, Xuexin Zhang, Adam J Fike, Yin-Hu Wang, Kristen N Bricker, Anthony Y Tao, Ping Xin, Vonn Walter, Martin T Johnson, Trayambak Pathak, Adam C Straub, Stefan Feske, Ziaur SM Rahman, Mohamed Trebak
Publikováno v:
eLife, Vol 12 (2023)
The essential role of store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE and their downstream signaling functions in B
Externí odkaz:
https://doaj.org/article/5b4624a722da497c9f2661a9b380baec
Autor:
Anthony Nguyen, Youngjae Sung, Sung Hee Lee, Charlotte Ellen Martin, Sonal Srikanth, Wei Chen, Mo K. Kang, Reuben H. Kim, No-Hee Park, Yousang Gwack, Yong Kim, Ki-Hyuk Shin
Publikováno v:
Cells, Vol 12, Iss 18, p 2225 (2023)
Emerging evidence indicates that intracellular calcium (Ca2+) levels and their regulatory proteins play essential roles in normal stem cell proliferation and differentiation. Cancer stem-like cells (CSCs) are subpopulations of cancer cells that retai
Externí odkaz:
https://doaj.org/article/b14d999550cc4a078bcec75e8a8e8934
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 8 (2021)
Background Orai3 is a mammalian‐specific member of the Orai family (Orai1‒3) and a component of the store‐operated Ca2+ entry channels. There is little understanding of the role of Orai channels in cardiomyocytes, and its role in cardiac functi
Externí odkaz:
https://doaj.org/article/11c6da05831a47faa74d700ab2a2f615
Autor:
Adéla Tiffner, Lena Maltan, Marc Fahrner, Matthias Sallinger, Sarah Weiß, Herwig Grabmayr, Carmen Höglinger, Isabella Derler
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
STIM1-mediated activation of calcium selective Orai channels is fundamental for life. The three Orai channel isoforms, Orai1-3, together with their multiple ways of interplay, ensure their highly versatile role in a variety of cellular functions and
Externí odkaz:
https://doaj.org/article/32d3b31dd9ba4d7482c14a4837ec3a62
Autor:
Mohamed Chamlali, Sana Kouba, Lise Rodat-Despoix, Luca Matteo Todesca, Zoltán Pethö, Albrecht Schwab, Halima Ouadid-Ahidouch
Publikováno v:
Cells, Vol 10, Iss 12, p 3487 (2021)
Orai3 calcium (Ca2+) channels are implicated in multiple breast cancer processes, such as proliferation and survival as well as resistance to chemotherapy. However, their involvement in the breast cancer cell migration processes remains vague. In the
Externí odkaz:
https://doaj.org/article/fec36aba3a24467da4ce2e62499c770d
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.