Zobrazeno 1 - 10
of 1 094
pro vyhledávání: '"OPTICAL RECONSTRUCTION MICROSCOPY"'
Autor:
Shihan Xu, Zhengrong Zhang, Bridgette C. Melvin, Nibedita Basu Ray, Seiko Ikezu, Tsuneya Ikezu
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 10, Pp n/a-n/a (2024)
Abstract The characterization of single extracellular vesicle (EV) has been an emerging tool for the early detection of various diseases despite there being challenges regarding how to interpret data with different protocols or instruments. In this w
Externí odkaz:
https://doaj.org/article/83a56c75aff84a7f9ec0fcfc18b0dbeb
Autor:
Ofir Sade, Daphna Fischel, Noa Barak-Broner, Shir Halevi, Irit Gottfried, Dana Bar-On, Stefan Sachs, Anat Mirelman, Avner Thaler, Aviv Gour, Meir Kestenbaum, Mali Gana Weisz, Saar Anis, Claudio Soto, Melanie Shanie Roitman, Shimon Shahar, Kathrin Doppler, Markus Sauer, Nir Giladi, Nirit Lev, Roy N. Alcalay, Sharon Hassin-Baer, Uri Ashery
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Alpha-synuclein (aSyn) aggregates in the central nervous system are the main pathological hallmark of Parkinson’s disease (PD). ASyn aggregates have also been detected in many peripheral tissues, including the skin, thus providing a novel and acces
Externí odkaz:
https://doaj.org/article/fb9c6cb2b32745928068125ebd86b591
Autor:
Anupam Bharadwaj, Amalesh Kumar, Sam Padalumavunkal Mathew, Rumela Mitra, Jina Bhattacharyya, Bithiah Grace Jaganathan, Bosanta R. Boruah
Publikováno v:
Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101798- (2024)
Fluorescence microscopy is an important tool for cell biology and cancer research. Present-day approach of implementing advanced optical microscopy methods combined with immunofluorescence labelling of specific proteins in cells is now able to delive
Externí odkaz:
https://doaj.org/article/e83c69c5f97c40ddb7906dc37481452d
Autor:
Yufei Wang, Alicia Buck, Brandon Piel, Luann Zerefa, Nithyassree Murugan, Christian D. Coherd, Andras G. Miklosi, Haraman Johal, Ricardo Nunes Bastos, Kun Huang, Miriam Ficial, Yasmin Nabil Laimon, Sabina Signoretti, Zhou Zhong, Song-My Hoang, Gabriella M. Kastrunes, Marion Grimaud, Atef Fayed, Hsien-Chi Yuan, Quang-De Nguyen, Tran Thai, Elena V. Ivanova, Cloud P. Paweletz, Ming-Ru Wu, Toni K. Choueiri, Jon O. Wee, Gordon J. Freeman, David A. Barbie, Wayne A. Marasco
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract One of the major hurdles that has hindered the success of chimeric antigen receptor (CAR) T cell therapies against solid tumors is on-target off-tumor (OTOT) toxicity due to sharing of the same epitopes on normal tissues. To elevate the safe
Externí odkaz:
https://doaj.org/article/90de263ab4864245afd1b4be5c061876
Autor:
Young, Kenneth Lee, II
Epithelial-mesenchymal transition (EMT) is a trans-differentiation program essential for development and wound healing that is pathologically activated during cancer progression. During this process, cells undergo complex changes at the transcription
Externí odkaz:
https://hdl.handle.net/10919/121357
Akademický článek
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Publikováno v:
Cells, Vol 13, Iss 17, p 1445 (2024)
Super-resolution single-molecule localization microscopy (SMLM) of presynaptic active zones (AZs) and postsynaptic densities contributed to the observation of protein nanoclusters that are involved in defining functional characteristics and in plasti
Externí odkaz:
https://doaj.org/article/e8bcc41a1a0c4316936b5c04d32ee493
Autor:
Øystein Øvrebø, Miina Ojansivu, Kimmo Kartasalo, Hanna M. G. Barriga, Petter Ranefall, Margaret N. Holme, Molly M. Stevens
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background Stochastic optical reconstruction microscopy (STORM), a super-resolution microscopy technique based on single-molecule localizations, has become popular to characterize sub-diffraction limit targets. However, due to lengthy image
Externí odkaz:
https://doaj.org/article/22d04680a034445f873b0e70e917aec8
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-17 (2023)
Abstract Background Regeneration of defective neurons in central nervous system is a highlighted issue for neurodegenerative disease treatment. Various tissue engineering approaches have focused on neuritogenesis to achieve the regeneration of damage
Externí odkaz:
https://doaj.org/article/bea78931df29459a814dc9605dd8b939
Autor:
Zhengrong Zhang, Kaiwen Yu, Yang You, Peizhou Jiang, Zhiping Wu, Michael A. DeTure, Dennis W. Dickson, Seiko Ikezu, Junmin Peng, Tsuneya Ikezu
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 8, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EVs) have emerged as critical mediators of intercellular communication and promising biomarkers and therapeutics in the central nervous system (CNS). Human brain‐derived EVs (BDEVs) provide a comprehensive snapshot
Externí odkaz:
https://doaj.org/article/2a73702a341a42eabd1eeba781c4b983