Zobrazeno 1 - 10
of 128
pro vyhledávání: '"OP9"'
Publikováno v:
BMC Molecular and Cell Biology, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background OP9 mouse stromal cell line has been widely used to induce differentiation of human embryonic stem cells (hESCs) into hematopoietic stem/progenitor cells (HSPCs). However, the whole co-culture procedure usually needs 14–18 days,
Externí odkaz:
https://doaj.org/article/3c479163d2bc4b8992df516524e7be36
Publikováno v:
Journal of Mazandaran University of Medical Sciences, Vol 32, Iss 216, Pp 1-19 (2023)
Background and purpose: Human pluripotent stem cells (hPSCs) with the ability to differentiate into adult cells have provided a new perspective for treatment of some diseases. But, the efficiency of differentiation methods to generate hematopoietic p
Externí odkaz:
https://doaj.org/article/b7aa173638874552981b7448c0acd938
Autor:
Yutong Chen, Weicheng Meng, Guangming Ren, Ning An, Jing Zhang, Zhixin Liu, Xiaoshuang Wu, Wen Yin, Xingbin Hu, Zheng Liu, Fan Feng, Yaozhen Chen
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e18038- (2023)
Mesenchymal stem cells (MSCs) are becoming more popular in therapy. Therefore, in-depth studies on mesenchymal stem cells in therapy are urgently needed. However, the difficulty in culturing and propagating MSCs in vitro complicates potential studies
Externí odkaz:
https://doaj.org/article/0d74c2532dec4e55a4495f19273dfbdf
Akademický článek
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Autor:
Josefine Tratwal, Guillaume Falgayrac, Alexandrine During, Nicolas Bertheaume, Charles Bataclan, Daniel N. Tavakol, Vasco Campos, Ludovic Duponchel, George Q. Daley, Guillaume Penel, Christophe Chauveau, Olaia Naveiras
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Bone marrow adipocytes (BMAds) constitute the most abundant stromal component of adult human bone marrow. Two subtypes of BMAds have been described, the more labile regulated adipocytes (rBMAds) and the more stable constitutive adipocytes (cBMAds), w
Externí odkaz:
https://doaj.org/article/4902e5f201334c0e8c7482fd57750abb
Autor:
Kae Sato, Momoko Maeda, Eriko Kamata, Sayaka Ishii, Kanako Yanagisawa, Kenji Kitajima, Takahiko Hara
Publikováno v:
Micromachines, Vol 11, Iss 3, p 305 (2020)
A microfluidic co-culture system, consisting of mouse embryonic stem cells (mESCs)/OP9 cells, was evaluated as a platform for studying hematopoietic differentiation mechanisms in vitro. mESC differentiation into blood cells was achieved in a microcha
Externí odkaz:
https://doaj.org/article/3049869068044b8b9e802262059b021e
Akademický článek
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Autor:
Xiaoli Chen, Qianhao Zhao, Chen Li, Yang Geng, Ke Huang, Jian Zhang, Xiaoshan Wang, Jiaqi Yang, Tongjie Wang, Chengxiang Xia, Xiaofei Liu, Minghui Meng, Dan Yang, Yi Zheng, Juan Du, Xiangzhong Zhang, Jiekai Chen, Guangjin Pan, Jinyong Wang
Publikováno v:
Stem Cell Research, Vol 15, Iss 2, Pp 395-402 (2015)
Generating engraftable hematopoietic stem cells (HSCs) from pluripotent stem cells (PSCs) is an ideal approach for obtaining induced HSCs for cell therapy. However, the path from PSCs to robustly induced HSCs (iHSCs) in vitro remains elusive. We hypo
Externí odkaz:
https://doaj.org/article/4492fe1621b54b62b2aace7752943b04
Akademický článek
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Publikováno v:
Journal of Lipid Research, Vol 54, Iss 3, Pp 823-830 (2013)
The hydroxy-carboxylic acid receptor (HCA1) is a G protein-coupled receptor that is highly expressed on adipocytes and considered a potential target for the treatment of dyslipidemia. In the current study, we investigated the pharmacological properti
Externí odkaz:
https://doaj.org/article/ddb9cf2c90a84fd2a0981d13c1201029