Zobrazeno 1 - 10
of 9 939
pro vyhledávání: '"ONL, outer nuclear layer"'
Autor:
Lu, Zhongyang1 (AUTHOR) zlu@oculogenex.com, Morales, Maria G.1 (AUTHOR) gmorales@oculogenex.com, Liu, Shufeng1 (AUTHOR), Ramkumar, Hema L.1 (AUTHOR) zlu@oculogenex.com
Publikováno v:
Cells (2073-4409). Oct2024, Vol. 13 Issue 19, p1672. 9p.
Autor:
Mervyn G Thomas, Frank A Proudlock, Irene Gottlob, Catey Bunce, Helena Lee, Sohaib R Rufai, Ravi Purohit
Publikováno v:
Ophthalmology
Purpose To evaluate structural grading and quantitative segmentation of foveal hypoplasia using handheld OCT, versus preferential looking (PL), as predictors of future vision in preverbal children with infantile nystagmus. Design Longitudinal cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1d3d2c93dba5652f105bd3576d2237
https://doi.org/10.1016/j.ophtha.2019.10.037
https://doi.org/10.1016/j.ophtha.2019.10.037
Publikováno v:
The Journal of Biological Chemistry
Different forms of photoreceptor degeneration cause blindness. Retinal degeneration-3 protein (RD3) deficiency in photoreceptors leads to recessive congenital blindness. We proposed that aberrant activation of the retinal membrane guanylyl cyclase (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777ae28d6c427ff826d869780f9a510f
http://europepmc.org/articles/PMC8517212
http://europepmc.org/articles/PMC8517212
Autor:
Wolfgang Baehr, Cecilia D. Gerstner, Ali Sakawa Sharif, Jeanne M. Frederick, Martha A. Cady, Vadim Y. Arshavsky, Christina Anne Mitchell, Guoxin Ying
Publikováno v:
The Journal of Biological Chemistry
INPP5E, also known as pharbin, is a ubiquitously expressed phosphatidylinositol polyphosphate 5-phosphatase that is typically located in the primary cilia and modulates the phosphoinositide composition of membranes. Mutations to or loss of INPP5E is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a678b53f03ba002421b1df8a573c65a1
http://europepmc.org/articles/PMC8047226
http://europepmc.org/articles/PMC8047226
Autor:
Hye Jin Kim, Joshua L. Dunaief, Keiko Ueda, Janet R. Sparrow, Diego Montenegro, Jin Zhao, Kevin Zhang
Publikováno v:
The Journal of Biological Chemistry
The ability of iron to transfer electrons enables the contribution of this metal to a variety of cellular activities even as the redox properties of iron are also responsible for the generation of hydroxyl radicals (•OH), the most destructive of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba35195fd6a8c8394dc2511e49becd4c
https://pubmed.ncbi.nlm.nih.gov/33402423
https://pubmed.ncbi.nlm.nih.gov/33402423
Publikováno v:
The Journal of Biological Chemistry
The death of photoreceptor cells in dry age-related macular degeneration (AMD) and autosomal recessive Stargardt disease (STGD1) is closely associated with disruption in all-trans-retinal (atRAL) clearance in neural retina. In this study, we reveal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e528672cccb4554ebf9c4e807e79212a
https://pubmed.ncbi.nlm.nih.gov/33334878
https://pubmed.ncbi.nlm.nih.gov/33334878
Publikováno v:
The Journal of Biological Chemistry
The Musashi family of RNA-binding proteins is known for its role in stem-cell renewal and is a negative regulator of cell differentiation. Interestingly, in the retina, the Musashi proteins MSI1 and MSI2 are differentially expressed throughout the cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f070897ca97db41205f1aa5a154f874
https://pubmed.ncbi.nlm.nih.gov/33168629
https://pubmed.ncbi.nlm.nih.gov/33168629
Autor:
Tsutomu Ohashi, Kazuhiko Namekata, Xiaoli Guo, Atsuko Kimura, Chikako Harada, Takayuki Harada
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 29, Iss, Pp 101197-(2022)
Biochemistry and Biophysics Reports, Vol 29, Iss, Pp 101197-(2022)
Lighting conditions may affect the development of retinal degenerative diseases such as macular degeneration. In this study, to determine whether the lighting environment affects the progression of degeneration of retinal ganglion cells (RGCs), we ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f1ad820997cd39a992a3adb270590a
https://doi.org/10.1016/j.bbrep.2021.101197
https://doi.org/10.1016/j.bbrep.2021.101197
Autor:
Binxiang Cai, Chunyan Liao, Danxue He, Jingmeng Chen, Jiahuai Han, Jiaying Lu, Kaiqi Qin, Wenxu Liang, Xiaoling Wu, Zuguo Liu, Yalin Wu
Publikováno v:
The Journal of Biological Chemistry
The breakdown of all-trans-retinal (atRAL) clearance is closely associated with photoreceptor cell death in dry age-related macular degeneration (AMD) and autosomal recessive Stargardt's disease (STGD1), but its mechanisms remain elusive. Here, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b29afe488a258683562e75a6793061
https://doi.org/10.1016/j.jbc.2021.101553
https://doi.org/10.1016/j.jbc.2021.101553
Autor:
Hiroshi Sagara, Hiroshi Kuribayashi, Fumie Hamano, Katsuyuki Nagata, Hideo Shindou, Toshiro Iwagawa, Sumiko Watanabe, Asano Tsuhako, Takao Shimizu
Publikováno v:
The Journal of Biological Chemistry
Membrane phospholipids play pivotal roles in various cellular processes, and their levels are tightly regulated. In the retina, phospholipids had been scrutinized because of their distinct composition and requirement in visual transduction. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6c7d130ab644213d3673ad9040d2c4
https://doi.org/10.1016/j.jbc.2021.100303
https://doi.org/10.1016/j.jbc.2021.100303