Zobrazeno 1 - 10
of 36
pro vyhledávání: '"OM P. MALHOTRA"'
Publikováno v:
Journal of Protein Chemistry. 14:537-548
The interaction of bovine prothrombin with Ca2+ and Mg2+ ions was investigated by following H+ release as a function of metal ion concentration at pH 6 and pH 7.4 at high and low ionic strength. Prothrombin Ca2+ and Mg2+ binding is characterized by h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0606afb5c46a9357f46167740271643e
https://doi.org/10.1007/bf01886880
https://doi.org/10.1007/bf01886880
Autor:
Om P. Malhotra
Publikováno v:
Biochemistry and Cell Biology. 69:404-408
The relationship of prothrombin structure to function with respect to γ-carboxyglutamic acid (Gla) residues can be effectively evaluated by characterizing the behavior of prothrombin isomers differing in Gla content. In addition to the isolation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e16521f3819adb6c42d47eb03b5eaa
https://doi.org/10.1139/o91-061
https://doi.org/10.1139/o91-061
Publikováno v:
Journal of Protein Chemistry. 10:31-41
Ca2+ titrations of the intrinsic fluorescence of a series of gamma-carboxyglutamic acid (GLA)-deficient bovine prothrombin fragments 1 yield response Hill plot parameters useful for characterization of the metal ion-binding process. 11-, 10-, and 9-G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0ef202ce93c4a9c76ba3b5729ae456
https://doi.org/10.1007/bf01024653
https://doi.org/10.1007/bf01024653
Autor:
Om P. Malhotra
Publikováno v:
Biochemistry and Cell Biology. 68:705-715
The role of γ-carboxyglutamic acid (Gla) in prothrombin function can be effectively evaluated by characterizing dicoumarol-induced, Gla-deficient prothrombin structural isomers. In addition to the isolation of 8-, 7-, 6-, 5-, 3-, 2-, 1-, and 0-Gla i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7967d41c4cc9d76718db478fdf81ce27
https://doi.org/10.1139/o90-102
https://doi.org/10.1139/o90-102
Phosphoglycerate-kinase-glyceraldehyde-3-phosphate-dehydrogenase interaction. Molecular mass studies
Publikováno v:
European journal of biochemistry. 227(1-2)
When rabbit muscle phosphoglycerate kinase (PGK; a 48-kDa monomeric protein) and glyceraldehyde-3-phosphate dehydrogenase (GraPDH; a 145-kDa homotetrameric protein) are present together in solution in the proportion of 1 mol PGK/1 mol GraPDH monomer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0731aa5b6bce76c91740b2e5c0ebdf11
https://pubmed.ncbi.nlm.nih.gov/7851437
https://pubmed.ncbi.nlm.nih.gov/7851437
Publikováno v:
American Journal of Hematology. 42:232-233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58f26f375dbb7899c4bb2a0bc9334ec7
https://doi.org/10.1002/ajh.2830420221
https://doi.org/10.1002/ajh.2830420221
Autor:
Om P. Malhotra
Publikováno v:
Thrombosis Research. 15:427-437
Barium citrate atypical prothrombin purified by our modified procedure, showed a single component by several criteria of purity. The variant was similar to normal prothrombin in: molecular mass (70,000 daltons), antigenic activity, carboxyl terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb279335538e7579ff8612d260f970c6
https://doi.org/10.1016/0049-3848(79)90149-x
https://doi.org/10.1016/0049-3848(79)90149-x
Autor:
Oscar Sudilovsky, Om P. Malhotra
Publikováno v:
Thrombosis Research. 47:501-510
Hybridoma technology was used for the production of murine monoclonal antibodies to bovine normal prothrombin. Hybrid cell cultures were assayed for the production of antibodies, both in the absence and presence of calcium ions, by Enzyme-Linked Immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a45c2a6410d10720278bd8f901bdee88
https://doi.org/10.1016/0049-3848(87)90356-2
https://doi.org/10.1016/0049-3848(87)90356-2
Publikováno v:
Thrombosis Research. 18:131-137
Under carefully controlled conditions and with standard comparable amounts of purified Factor Xa + Factor V + Phospholipid and calcium ions, the yield of thrombin was incomplete and approximately the same from purified prothrombin, purified prethromb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d8871ab3fd597fad56b6fed5585b8e
https://doi.org/10.1016/0049-3848(80)90177-2
https://doi.org/10.1016/0049-3848(80)90177-2
Autor:
Om P. Malhotra
Publikováno v:
Thrombosis Research. 47:485-492
A 5-Gla prothrombin, adsorbable onto barium oxalate and containing an admixture of one- and two-chain molecules, has been purified from the plasma of steers on a dicoumarol regimen for three years. Double-chain molecules were not detected in any of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7591f81ade9268494aa25c0d67886814
https://doi.org/10.1016/0049-3848(87)90354-9
https://doi.org/10.1016/0049-3848(87)90354-9