Zobrazeno 1 - 10
of 1 691
pro vyhledávání: '"OLIVIER E"'
Autor:
Aurélie Joussaume, Chryso Kanthou, Olivier E. Pardo, Lucie Karayan-Tapon, Omar Benzakour, Fatima Dkhissi
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 3278-3293 (2024)
Protein S (PROS1) is a vitamin K-dependent anticoagulant factor, which also acts as an agonist for the TYRO3, AXL, and MERTK (TAM) tyrosine kinase receptors. PROS1 is produced by the endothelium which also expresses TAM receptors, but little is known
Externí odkaz:
https://doaj.org/article/7eb8813ce6a24d078a0b98f358bbfe47
Autor:
Natalie F. Shur, Elizabeth J. Simpson, Hannah Crossland, Despina Constantin, Sally M. Cordon, Dumitru Constantin‐Teodosiu, Francis B. Stephens, Matthew S. Brook, Philip J. Atherton, Kenneth Smith, Daniel J. Wilkinson, Olivier E. Mougin, Christopher Bradley, Ian A. Macdonald, Paul L. Greenhaff
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 603-614 (2024)
Abstract Background Bed‐rest (BR) of only a few days duration reduces muscle protein synthesis and induces skeletal muscle atrophy and insulin resistance, but the scale and juxtaposition of these events have not been investigated concurrently in th
Externí odkaz:
https://doaj.org/article/d580a30a9b8542378951c31db57ce3e4
Autor:
Yakinthi Chrisochoidou, Rajat Roy, Pooyeh Farahmand, Guadalupe Gonzalez, Jennifer Doig, Lukas Krasny, Ella F. Rimmer, Anne E Willis, Marion MacFarlane, Paul H. Huang, Neil O. Carragher, Alison F. Munro, Daniel J. Murphy, Kirill Veselkov, Michael J. Seckl, Miriam F. Moffatt, William O. C. Cookson, Olivier E. Pardo
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-20 (2023)
Abstract Mesothelioma is an aggressive cancer of the mesothelial layer associated with an extensive fibrotic response. The latter is in large part mediated by cancer-associated fibroblasts which mediate tumour progression and poor prognosis. However,
Externí odkaz:
https://doaj.org/article/aaf6d7ac3e1a4d1b86de96ee85ac0b92
Autor:
Judith Schaf, Sonia Shinhmar, Qingyu Zeng, Olivier E. Pardo, Philip Beesley, Nelofer Syed, Robin S. B. Williams
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Glioblastomas are a highly aggressive cancer type which respond poorly to current pharmaceutical treatments, thus novel therapeutic approaches need to be investigated. One such approach involves the use of the bioactive natural product Tansh
Externí odkaz:
https://doaj.org/article/eb1ae5def32c41aba2ef94e86feb2080
Autor:
DING Lai-feng, ZHANG Cong-cong, HU Qing-yu, Olivier E. PARDO, Michael J. SECKL, WANG Yu-lan, WU Jun-fang
Publikováno v:
Chinese Journal of Magnetic Resonance, Vol 36, Iss 04, Pp 534-543 (2019)
Choriocarcinoma (CC) is a malignant trophoblastic tumor that occurs in women of childbearing age. Its cure rate could be over 90% following single drug or multidrug chemotherapy with methotrexate, 5-fluorouracil and etc. Chemoresistance is the main c
Externí odkaz:
https://doaj.org/article/fef24166b25849d0a1ea9e0d984ee7cf
Autor:
Olivier E van der Cammen, Steve P Chobo, Justine S Kasitu, Ipyana Mwampagatwa, Rob Mooij, Myrrith H Hulsbergen
Publikováno v:
Journal of Global Health Reports, Vol 5 (2021)
# Background After the introduction of the maternal near-miss (MNM) criteria by the World Health Organization (WHO), an adapted version for low-income countries was defined but has never been validated in a rural hospital in this setting. Aim of this
Externí odkaz:
https://doaj.org/article/ec7865201cbd4ffa8eb6a7ac7821cb26
Autor:
Guy Griebel, Jeanne Stemmelin, Mati Lopez-Grancha, Valérie Fauchey, Franck Slowinski, Philippe Pichat, Gihad Dargazanli, Ahmed Abouabdellah, Caroline Cohen, Olivier E. Bergis
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-25 (2018)
Abstract Enhancing endogenous cannabinoid (eCB) signaling has been considered as a potential strategy for the treatment of stress-related conditions. Fatty acid amide hydrolase (FAAH) represents the primary degradation enzyme of the eCB anandamide (A
Externí odkaz:
https://doaj.org/article/080f7bdc1656430e82c1cafc30cdcfa0
Autor:
Ioannis Poursaitidis, Xiaomeng Wang, Thomas Crighton, Christiaan Labuschagne, David Mason, Shira L. Cramer, Kendra Triplett, Rajat Roy, Olivier E. Pardo, Michael J. Seckl, Scott W. Rowlinson, Everett Stone, Richard F. Lamb
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2547-2556 (2017)
Cancer cells reprogram their metabolism, altering both uptake and utilization of extracellular nutrients. We individually depleted amino acid nutrients from isogenic cells expressing commonly activated oncogenes to identify correspondences between nu
Externí odkaz:
https://doaj.org/article/b6f55eb2c70d46c98ead05bb14f9b075
Autor:
Olivier E. Nonga, Darja Lavogina, Erki Enkvist, Katrin Kestav, Apirat Chaikuad, Sarah E. Dixon-Clarke, Alex N. Bullock, Sergei Kopanchuk, Taavi Ivan, Ramesh Ekambaram, Kaido Viht, Stefan Knapp, Asko Uri
Publikováno v:
Molecules, Vol 26, Iss 14, p 4353 (2021)
We performed an X-ray crystallographic study of complexes of protein kinase PIM-1 with three inhibitors comprising an adenosine mimetic moiety, a linker, and a peptide-mimetic (d-Arg)6 fragment. Guided by the structural models, simplified chemical st
Externí odkaz:
https://doaj.org/article/a3a8d1a0bd22472d8e0cc873fa4e2ef8
Autor:
Linda O'Flaherty, Steven D Shnyder, Patricia A Cooper, Stephen J Cross, James G Wakefield, Olivier E Pardo, Michael J Seckl, Jeremy M Tavaré
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214610 (2019)
Glycogen synthase kinase-3 (GSK3) is over-expressed and hyperactivated in non-small cell lung carcinoma (NSCLC) and plays a role in ensuring the correct alignment of chromosomes on the metaphase plate during mitosis through regulation of microtubule
Externí odkaz:
https://doaj.org/article/dc7e05d61ac94dc89ab7433046f32c07