Zobrazeno 1 - 10
of 712
pro vyhledávání: '"OLIVER FIEHN"'
Autor:
Sita Manasa Susarla, Oliver Fiehn, Ines Thiele, Amanda L. Ngo, Dinesh K. Barupal, Rana F. Chehab, Assiamira Ferrara, Yeyi Zhu
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Pre-diagnostic disturbances in the microbiome-derived metabolome have been associated with an increased risk of diabetes in non-pregnant populations. However, the roles of microbiome-derived metabolites, the end-products of microb
Externí odkaz:
https://doaj.org/article/60c3692470764fde96e3764b7f3c0e9c
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Posttraumatic stress disorder (PTSD) can develop after trauma exposure. Some studies report that women develop PTSD at twice the rate of men, despite greater trauma exposure in men. Lipids and their metabolites (lipidome) regulate a myriad o
Externí odkaz:
https://doaj.org/article/80455f06f7f24acab5b6b72f3dbfea00
Publikováno v:
F1000Research, Vol 13 (2024)
Background Glioblastoma (GBM) is a clinically challenging primary brain tumor with poor survival outcome despite surgical resection and intensive chemoradiation. The metabolic heterogeneity of GBM can become biomarkers for treatment response, resista
Externí odkaz:
https://doaj.org/article/a0203848f90049648c4cd889f913fd83
Autor:
Maria Questa, Bart C. Weimer, Oliver Fiehn, Betty Chow, Steve L. Hill, Mark R. Ackermann, Jonathan A. Lidbury, Joerg M. Steiner, Jan S. Suchodolski, Sina Marsilio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Chronic enteropathies (CE) are common disorders in cats and the differentiation between the two main underlying diseases, inflammatory bowel disease (IBD) and low-grade intestinal T-cell lymphoma (LGITL), can be challenging. Characterization
Externí odkaz:
https://doaj.org/article/80a5da879aac48788f005a3dc07b3e4f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract Biological interpretation of metabolomic datasets often ends at a pathway analysis step to find the over-represented metabolic pathways in the list of statistically significant metabolites. However, definitions of biochemical pathways and me
Externí odkaz:
https://doaj.org/article/49e8c26a3019406c849c06c37f398170
Autor:
Oliver Fiehn
Publikováno v:
Metabolites, Vol 14, Iss 11, p 576 (2024)
This Special Issue was published to celebrate 10+ years of research and services at the UC Davis West Coast Metabolomics Center (WCMC) [...]
Externí odkaz:
https://doaj.org/article/c25ca188c35e418e953126393f774526
Autor:
Patrick M. Carry, Lauren A. Vanderlinden, Randi K. Johnson, Teresa Buckner, Andrea K. Steck, Katerina Kechris, Ivana V. Yang, Tasha E. Fingerlin, Oliver Fiehn, Marian Rewers, Jill M. Norris
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundType 1 diabetes (T1D) is preceded by a heterogenous pre-clinical phase, islet autoimmunity (IA). We aimed to identify pre vs. post-IA seroconversion (SV) changes in DNAm that differed across three IA progression phenotypes, those who lose a
Externí odkaz:
https://doaj.org/article/13d1cee8ffcf44c0a63da89f47ca487c
Autor:
Arpana Vaniya, Anja Karlstaedt, Damla Gulkok, Tilo Thottakara, Yamin Liu, Sili Fan, Hannah Eades, Styliani Vakrou, Ryuya Fukunaga, Hilary J. Vernon, Oliver Fiehn, M. Roselle Abraham
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 8, Iss , Pp 100073- (2024)
Introduction: Hypertrophic cardiomyopathy (HCM) results from pathogenic variants in sarcomeric protein genes that increase myocyte energy demand and lead to cardiac hypertrophy. However, it is unknown whether a common metabolic trait underlies cardia
Externí odkaz:
https://doaj.org/article/d8cb9d6dcd734514bb112086143d8f7d
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30452- (2024)
Parkinson's disease (PD) is a prevalent neurodegenerative disorder with a poorly understood etiology. An accurate diagnosis of idiopathic PD remains challenging as misdiagnosis is common in routine clinical practice. Moreover, current therapeutics fo
Externí odkaz:
https://doaj.org/article/44d3cf5696924c7b864946b0ec59477c
Autor:
Jayce E. Taylor, Dileep Sai Kumar Palur, Angela Zhang, Jake N. Gonzales, Augustine Arredondo, Timothy A. Coulther, Amiruddin Bin Johan Lechner, Elys P. Rodriguez, Oliver Fiehn, John Didzbalis, Justin B. Siegel, Shota Atsumi
Publikováno v:
npj Science of Food, Vol 7, Iss 1, Pp 1-12 (2023)
Abstract Due to the rampant rise in obesity and diabetes, consumers are desperately seeking for ways to reduce their sugar intake, but to date there are no options that are both accessible and without sacrifice of palatability. One of the most promis
Externí odkaz:
https://doaj.org/article/190e204543a54d8ebf6cc3d4736209cb