Zobrazeno 1 - 10
of 722
pro vyhledávání: '"OLIVER FIEHN"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Posttraumatic stress disorder (PTSD) can develop after trauma exposure. Some studies report that women develop PTSD at twice the rate of men, despite greater trauma exposure in men. Lipids and their metabolites (lipidome) regulate a myriad o
Externí odkaz:
https://doaj.org/article/80455f06f7f24acab5b6b72f3dbfea00
Autor:
Maria Questa, Bart C. Weimer, Oliver Fiehn, Betty Chow, Steve L. Hill, Mark R. Ackermann, Jonathan A. Lidbury, Joerg M. Steiner, Jan S. Suchodolski, Sina Marsilio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Chronic enteropathies (CE) are common disorders in cats and the differentiation between the two main underlying diseases, inflammatory bowel disease (IBD) and low-grade intestinal T-cell lymphoma (LGITL), can be challenging. Characterization
Externí odkaz:
https://doaj.org/article/80a5da879aac48788f005a3dc07b3e4f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract Biological interpretation of metabolomic datasets often ends at a pathway analysis step to find the over-represented metabolic pathways in the list of statistically significant metabolites. However, definitions of biochemical pathways and me
Externí odkaz:
https://doaj.org/article/49e8c26a3019406c849c06c37f398170
Autor:
Patrick M. Carry, Lauren A. Vanderlinden, Randi K. Johnson, Teresa Buckner, Andrea K. Steck, Katerina Kechris, Ivana V. Yang, Tasha E. Fingerlin, Oliver Fiehn, Marian Rewers, Jill M. Norris
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundType 1 diabetes (T1D) is preceded by a heterogenous pre-clinical phase, islet autoimmunity (IA). We aimed to identify pre vs. post-IA seroconversion (SV) changes in DNAm that differed across three IA progression phenotypes, those who lose a
Externí odkaz:
https://doaj.org/article/13d1cee8ffcf44c0a63da89f47ca487c
Autor:
Arpana Vaniya, Anja Karlstaedt, Damla Gulkok, Tilo Thottakara, Yamin Liu, Sili Fan, Hannah Eades, Styliani Vakrou, Ryuya Fukunaga, Hilary J. Vernon, Oliver Fiehn, M. Roselle Abraham
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 8, Iss , Pp 100073- (2024)
Introduction: Hypertrophic cardiomyopathy (HCM) results from pathogenic variants in sarcomeric protein genes that increase myocyte energy demand and lead to cardiac hypertrophy. However, it is unknown whether a common metabolic trait underlies cardia
Externí odkaz:
https://doaj.org/article/d8cb9d6dcd734514bb112086143d8f7d
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30452- (2024)
Parkinson's disease (PD) is a prevalent neurodegenerative disorder with a poorly understood etiology. An accurate diagnosis of idiopathic PD remains challenging as misdiagnosis is common in routine clinical practice. Moreover, current therapeutics fo
Externí odkaz:
https://doaj.org/article/44d3cf5696924c7b864946b0ec59477c
Autor:
Jayce E. Taylor, Dileep Sai Kumar Palur, Angela Zhang, Jake N. Gonzales, Augustine Arredondo, Timothy A. Coulther, Amiruddin Bin Johan Lechner, Elys P. Rodriguez, Oliver Fiehn, John Didzbalis, Justin B. Siegel, Shota Atsumi
Publikováno v:
npj Science of Food, Vol 7, Iss 1, Pp 1-12 (2023)
Abstract Due to the rampant rise in obesity and diabetes, consumers are desperately seeking for ways to reduce their sugar intake, but to date there are no options that are both accessible and without sacrifice of palatability. One of the most promis
Externí odkaz:
https://doaj.org/article/190e204543a54d8ebf6cc3d4736209cb
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8810 (2024)
Hypertriglyceridemia is a risk factor for type 2 diabetes and cardiovascular disease (CVD). Plasma triglycerides (TGs) are a key factor for assessing the risk of diabetes or CVD. However, previous lipidomics studies have demonstrated that not all TG
Externí odkaz:
https://doaj.org/article/e70a86777fa541e08cf18c6eed196bd0
Autor:
Guanhong Miao, Raimund Pechlaner, Oliver Fiehn, Kimberly M. Malloy, Ying Zhang, Jason G. Umans, Manuel Mayr, Johann Willeit, Stefan Kiechl, Jinying Zhao
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)
Background Dyslipidemia is an independent risk factor for coronary heart disease (CHD). Standard lipid panel cannot capture the complexity of the blood lipidome (ie, all molecular lipids in the blood). To date, very few large‐scale epidemiological
Externí odkaz:
https://doaj.org/article/bb5f5b085ef44c80a5ea23240606d18b
Publikováno v:
Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Metabolomics by gas chromatography/mass spectrometry (GC/MS) provides a standardized and reliable platform for understanding small molecule biology. Since 2005, the West Coast Metabolomics Center at the University of California at Davis has
Externí odkaz:
https://doaj.org/article/8b784381af4f4adaa3231dadcd7732f3