Zobrazeno 1 - 10
of 14
pro vyhledávání: '"OE, overexpression"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 1, Pp 169-180 (2021)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Primary cilium is a microtubule-based organelle that projects from the surfaces of most mammalian cell types and protrudes into the extracellular milieu as an antenna-like sensor to senses extracellular physical and biochemical signals, and then tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361470a71f476fd73c328cb0a2367cb3
http://www.sciencedirect.com/science/article/pii/S1476558620301834
http://www.sciencedirect.com/science/article/pii/S1476558620301834
Publikováno v:
The Journal of Biological Chemistry
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Funding Information: Funding and additional information—C. G. A. has obtained funding from Maratona da Saúde 2016; CEECIND/00410/2017 financed by FCT (Portugal); ALZ AARG-19–618007 (Alzheimer’s Association); the European Union’s Horizon 2020
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2de6c2693d9bec20fda2c7ec0e76d7c
https://hdl.handle.net/10362/125755
https://hdl.handle.net/10362/125755
Autor:
Robert Damoiseaux, Yenni A Garcia, Bobby Tofig, Ivan Ramirez, Erick F. Velasquez, Xiao Guo, Jorge Z. Torres, Whitaker Cohn, Ankur A. Gholkar, Julian P. Whitelegge
Publikováno v:
The Journal of Biological Chemistry
Human cell division is a highly regulated process that relies on the accurate capture and movement of chromosomes to the metaphase plate. Errors in the fidelity of chromosome congression and alignment can lead to improper chromosome segregation, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119f472aa7d28b25f00860fcbe90d0af
http://europepmc.org/articles/PMC8131738
http://europepmc.org/articles/PMC8131738
Autor:
Sjoerd J L van Wijk, Simone Fulda, Birte Jeiler, Jens Roedig, Nadezda Dolgikh, Annkathrin Koch
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 539-550 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 5, Pp 539-550 (2021)
Burkitt's lymphoma (BL) is a highly aggressive form of B-cell non-Hodgkin's lymphoma. The clinical outcome in children with BL has improved over the last years but the prognosis for adults is still poor, highlighting the need for novel treatment stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65da807d73e5d104985297a80089959
https://pubmed.ncbi.nlm.nih.gov/33971465
https://pubmed.ncbi.nlm.nih.gov/33971465
Publikováno v:
The Journal of Biological Chemistry
Traditionally, lipolysis has been regarded as an enzymatic activity that liberates fatty acids as metabolic fuel. However, recent work has shown that novel substrates, including a variety of lipid compounds such as fatty acids and their derivatives,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843afc812038c7071cb5c29c54353e0a
http://europepmc.org/articles/PMC7949114
http://europepmc.org/articles/PMC7949114
Publikováno v:
The Journal of Biological Chemistry
The clinical efficacy of docetaxel (DTX) in prostate cancer treatment is barely satisfactory due to diverse responses of the patients, including the development of resistance. Recently, aberrant androgen receptor (AR) signaling, including expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb336f284faf35fb532b50797dcc2006
https://pubmed.ncbi.nlm.nih.gov/33428943
https://pubmed.ncbi.nlm.nih.gov/33428943
Autor:
Fabiana Passaro, Federico Zambelli, Matteo Barbato, Giorgia Di Benedetto, Silvia Parisi, Tommaso Russo, Davide Cacchiarelli, Anna Maria D'Erchia, Dario Antonini, Caterina Manzari, Margherita Mutarelli, Graziano Pesole, Ilaria De Martino
Publikováno v:
The Journal of Biological Chemistry
The Yes-associated protein (YAP), one of the major effectors of the Hippo pathway together with its related protein WW-domain-containing transcription regulator 1 (WWTR1; also known as TAZ), mediates a range of cellular processes from proliferation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa540f1714754a8bd14cee34fc3c58cc
https://pubmed.ncbi.nlm.nih.gov/33268382
https://pubmed.ncbi.nlm.nih.gov/33268382
Autor:
Michael R. Crowley, Asmi Chakraborty, Donald J. Buchsbaum, Austin D. Silva, Susan L. Bellis, Nikita Bhalerao, Colleen M. Britain, Yvonne J. K. Edwards, David K. Crossman
Publikováno v:
The Journal of Biological Chemistry
ST6Gal-I, an enzyme upregulated in numerous malignancies, adds α2-6-linked sialic acids to select membrane receptors, thereby modulating receptor signaling and cell phenotype. In this study, we investigated ST6Gal-I's role in epithelial to mesenchym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9edcede45860745dd7a00cf70de01157
https://pubmed.ncbi.nlm.nih.gov/33148698
https://pubmed.ncbi.nlm.nih.gov/33148698
Autor:
Chang Xiaohan, Fang Li, Lin Yang, Na Liu, Hua Li, Yifeng Zhou, Sihan Deng, Lankai Jing, Cai Yuhan
Publikováno v:
The Journal of Biological Chemistry
Circular RNAs (circRNAs) are a novel class of widespread noncoding RNAs that regulate gene expression in mammals. Recent studies demonstrate that functional peptides can be encoded by short open reading frames in noncoding RNAs, including circRNAs. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa2dc85e77c67be7d4d2b772641a4b0
https://doi.org/10.1016/j.jbc.2021.101182
https://doi.org/10.1016/j.jbc.2021.101182
Autor:
Mei Yang, Fei Gao, Yuqin Chen, Chunyu Wang, Tingjie Li, Xueting He, Hui Liu, Maoqi Wang, Jiaojiao Hou, Zhuoyuan Yu, Jiang Tan, Xiaoyan Liu
Publikováno v:
The Journal of Biological Chemistry
Metformin is the first-line antidiabetic agent for type 2 diabetes mellitus (T2DM) treatment. Although accumulated evidence has shed light on the consequences of metformin action, the precise mechanisms of its action, especially in the pancreas, are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb976ddce6a5fc7623f721d1f3d03bc
https://doi.org/10.1016/j.jbc.2021.101002
https://doi.org/10.1016/j.jbc.2021.101002