Zobrazeno 1 - 10
of 23
pro vyhledávání: '"ODE, ordinary differential equation"'
Publikováno v:
Frontiers in Soft Matter, Vol 4 (2024)
Affinity-mediated drug delivery utilizes electrostatic, hydrophobic, or other non-covalent interactions between molecules and a polymer to extend the timeframe of drug release. Cyclodextrin polymers exhibit affinity interaction, however, experimental
Externí odkaz:
https://doaj.org/article/eeca730ceeb14cf8a4cecf6f3675b0cf
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mechanistic learning refers to the synergistic combination of mechanistic mathematical modeling and data-driven machine or deep learning. This emerging field finds increasing applications in (mathematical) oncology. This review aims to capture the cu
Externí odkaz:
https://doaj.org/article/ca3883a94f2a48858a081698dd091425
Akademický článek
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Autor:
Veronika Voronova, Kirill Peskov, Victor Sokolov, Amani Al-Khaifi, Chanchal Kumar, Mats Rudling, Gabriel Helmlinger, Sara Straniero, Bo Angelin
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 149-170 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Disturbances of the enterohepatic circulation of bile acids (BAs) are seen in a number of clinically important conditions, including metabolic disorders, hepatic impairment, diarrhea, and gallstone disease. To facilitate the explora
Autor:
Ali M. Komai, Charlotta S. Olofsson, William Lövfors, Christian Simonsson, Elin Nyman, Gunnar Cedersund
Publikováno v:
The Journal of Biological Chemistry
Circulating levels of the adipocyte hormone adiponectin are typically reduced in obesity, and this deficiency has been linked to metabolic diseases. It is thus important to understand the mechanisms controlling adiponectin exocytosis. This understand
Akademický článek
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Publikováno v:
The Journal of Biological Chemistry
Heterodimeric KIF3AC is a mammalian kinesin-2 that is highly expressed in the central nervous system and associated with vesicles in neurons. KIF3AC is an intriguing member of the kinesin-2 family because the intrinsic kinetics of KIF3A and KIF3C whe
Autor:
Vaibhav Dhyani, Sarpras Swain, Rishikesh Kumar Gupta, Suman Gare, Kareenhalli V. Venkatesh, Lopamudra Giri
Publikováno v:
Cellular Signalling
G-protein coupled receptor (GPCR) mediated calcium (Ca2+)-signaling transduction remains crucial in designing drugs for various complex diseases including neurodegeneration, chronic heart failure as well as respiratory diseases. Although there are se
Akademický článek
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Autor:
Lin, Congping, Steinberg, Gero
Publikováno v:
Fungal Genetics and Biology
Highlights • Modelling of dynein motility reveals a stochastic role in dynein comet formation. • Modelling helps to elucidate mechanisms in spatial organization of early endosomes. • A combination of diffusion and directed motion distributes ri