Zobrazeno 1 - 10
of 75
pro vyhledávání: '"ODD S. GABRIELSEN"'
Autor:
Roza B. Lemma, Marit Ledsaak, Bettina M. Fuglerud, Geir Kjetil Sandve, Ragnhild Eskeland, Odd S. Gabrielsen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract The transcription factor MYB is a master regulator in haematopoietic progenitor cells and a pioneer factor affecting differentiation and proliferation of these cells. Leukaemic transformation may be promoted by high MYB levels. Despite much
Externí odkaz:
https://doaj.org/article/aff4d035089f405cb2b6a55119ff4841
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-15 (2018)
Abstract Background The concept of pioneer transcription factors is emerging as an essential part of the epigenetic regulation, taking place during cell development and differentiation. However, the precise molecular mechanism underlying pioneer fact
Externí odkaz:
https://doaj.org/article/517c5a6b37424159a06ae7037d383c04
Autor:
Vessela N. Kristensen, Odd S. Gabrielsen, Anne-Lise Børresen-Dale, Per Eystein Lønning, Ivo G. Gut, Zohar Yakhini, Elen M. Brendeford, Fredrik E. Johansen, Grethe I.G. Alnaes, Hiroko K. Solvang, Jörg Tost, Jo Anders Rønneberg
Supplementary Table 2 from GSTP1 Promoter Haplotypes Affect DNA Methylation Levels and Promoter Activity in Breast Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf59ebbede2d3531abf94e7f27575e5
https://doi.org/10.1158/0008-5472.22375028.v1
https://doi.org/10.1158/0008-5472.22375028.v1
Autor:
Vessela N. Kristensen, Odd S. Gabrielsen, Anne-Lise Børresen-Dale, Per Eystein Lønning, Ivo G. Gut, Zohar Yakhini, Elen M. Brendeford, Fredrik E. Johansen, Grethe I.G. Alnaes, Hiroko K. Solvang, Jörg Tost, Jo Anders Rønneberg
Supplementary Table 1 from GSTP1 Promoter Haplotypes Affect DNA Methylation Levels and Promoter Activity in Breast Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048f0f34f7c285e1f228c92e6745102b
https://doi.org/10.1158/0008-5472.22375031
https://doi.org/10.1158/0008-5472.22375031
Autor:
Vessela N. Kristensen, Odd S. Gabrielsen, Anne-Lise Børresen-Dale, Per Eystein Lønning, Ivo G. Gut, Zohar Yakhini, Elen M. Brendeford, Fredrik E. Johansen, Grethe I.G. Alnaes, Hiroko K. Solvang, Jörg Tost, Jo Anders Rønneberg
The CpG island spanning the transcription start of the glutathione S-transferase P1 becomes methylated in a variety of human cancers including breast cancer. To study the effect of sequence variation on hypermethylation of the GSTP1 promoter, we anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9adb3a430c985783b00d95a916167e72
https://doi.org/10.1158/0008-5472.c.6497681
https://doi.org/10.1158/0008-5472.c.6497681
Autor:
Vessela N. Kristensen, Odd S. Gabrielsen, Anne-Lise Børresen-Dale, Per Eystein Lønning, Ivo G. Gut, Zohar Yakhini, Elen M. Brendeford, Fredrik E. Johansen, Grethe I.G. Alnaes, Hiroko K. Solvang, Jörg Tost, Jo Anders Rønneberg
Supplementary Figure 1 from GSTP1 Promoter Haplotypes Affect DNA Methylation Levels and Promoter Activity in Breast Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4750367e1b2c6e56854079cd759e6bec
https://doi.org/10.1158/0008-5472.22375034.v1
https://doi.org/10.1158/0008-5472.22375034.v1
Autor:
Vessela N. Kristensen, Odd S. Gabrielsen, Anne-Lise Børresen-Dale, Per Eystein Lønning, Ivo G. Gut, Zohar Yakhini, Elen M. Brendeford, Fredrik E. Johansen, Grethe I.G. Alnaes, Hiroko K. Solvang, Jörg Tost, Jo Anders Rønneberg
Supplementary Table 4 from GSTP1 Promoter Haplotypes Affect DNA Methylation Levels and Promoter Activity in Breast Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ea9f393d8c006e1fce5283135db316
https://doi.org/10.1158/0008-5472.22375022.v1
https://doi.org/10.1158/0008-5472.22375022.v1
Autor:
Vessela N. Kristensen, Odd S. Gabrielsen, Anne-Lise Børresen-Dale, Per Eystein Lønning, Ivo G. Gut, Zohar Yakhini, Elen M. Brendeford, Fredrik E. Johansen, Grethe I.G. Alnaes, Hiroko K. Solvang, Jörg Tost, Jo Anders Rønneberg
Supplementary Table 3 from GSTP1 Promoter Haplotypes Affect DNA Methylation Levels and Promoter Activity in Breast Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650f0c6f3753edee2ff17cd6d8aaa701
https://doi.org/10.1158/0008-5472.22375025
https://doi.org/10.1158/0008-5472.22375025
MYB insufficiency disrupts proteostasis in hematopoietic stem cells leading to age-related neoplasia
Autor:
Roza Berhanu Lemma, Giacomo Volpe, Boris Noyvert, Odd S. Gabrielsen, Jon Frampton, Mary L. Clarke, David S. Walton
Publikováno v:
Blood.
MYB plays a key role in gene regulation throughout the hematopoietic hierarchy and is critical for the maintenance of normal hematopoietic stem cells (HSC). Acquired genetic dysregulation of MYB is involved in the etiology of a number of leukemias, a
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 10, Iss 11, Pp 2329-2342 (2020)
FEBS Open Bio, Vol 10, Iss 11, Pp 2329-2342 (2020)
Genes are activated by transcription factors through their transactivation domains (tADs); disordered regions that have been poorly understood. New models for tADs have recently been proposed. Here, these models were assessed through a mutational ana