Zobrazeno 1 - 10
of 40
pro vyhledávání: '"O.V. Lynchak"'
Autor:
N.V. Dziubenko, O.V. Lynchak, Olga Abramchuk, Svitlana Prylutska, I.V. Byelinska, H.M. Kuznietsova
Publikováno v:
Applied Nanoscience. 12:439-447
Acute toxicity of noncovalent nanocomplex of C60 fullerene with Cisplatin (Cis-Pt) (the ratio of compounds C60:Cis-Pt by weight 1:1) in a dose progression (7.5 + 7.5, 15.0 + 15.0, 22.5 + 22.5, 30.0 + 30.0, 37.5 + 37.5, and 45.0 + 45.0 mg/kg) was inve
Publikováno v:
Environment & Health. :14-20
For the effective and safe implementation of quarantine measures for the prevention of infectious diseases, it is necessary to a create the conditions for the maintenance of physical and mental health of the population, especially of the children and
Autor:
H.M. Kuznietsova, Volodymyr Rybalchenko, O.V. Lynchak, Vasyl V. Hurmach, I.V. Byelinska, Demyd S. Milokhov, O. V. Khilya, Natalia Dziubenko, A. Bychko
Publikováno v:
Journal of Drug Targeting. 28:547-563
Pyrrole derivatives (PDs) chloro-1-(4-chlorobenzyl)-4-((3-(trifluoromethyl)phenyl)amino)-1H-pyrrole-2,5-dione (MI-1) and 5-amino-4-(1,3-benzothyazol-2-yn)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrole-3-one (D1) were synthesised as inhibitors of several
Autor:
Tetyana S Herheliuk, Dmytro K Zavalny, Uwe Ritter, Yuriy Prylutskyy, Olga V Remeniak, H.M. Kuznietsova, Natalia Dziubenko, O.V. Lynchak
Publikováno v:
Digestive Diseases and Sciences. 65:215-224
A significant role in pathogenesis of cholangitis is attributed to excessive reactive oxygen species production and oxidative stress. Therefore, antioxidants could be promising therapeutics. The effects of powerful free radical scavenger C60 fulleren
Autor:
V. V. Cherepanov, Volodymyr Rybalchenko, Eric Täuscher, Anna Grebinyk, O. P. Matyshevska, O.V. Lynchak, Uwe Ritter, I.V. Byelinska, Svitlana Prylutska, Marcus Frohme, Yuriy I. Prylutskyy
Publikováno v:
Fullerenes, Nanotubes and Carbon Nanostructures. 27:715-728
Toxicity of the C60 fullerene aqueous colloid solution in vitro and in vivo experiments was studied. C60 fullerene in the concentration range of 3.6–144 µg/mL demonstrated low toxicity agai...
Autor:
V V Kostjukov, Uwe Ritter, Yu. I. Prylutskyy, O V Remeniak, O.V. Lynchak, Svitlana Prylutska, Maxim P. Evstigneev, Volodymyr Rybalchenko, Peter Scharff
Publikováno v:
Experimental Oncology. :106-111
Background Cisplatin (Cis-Pt) is a widely used anticancer drug but its therapeutic efficiency is limited by hemato-, cardio-, hepato-, nephro- and neurotoxicity. Complexation of Cis-Pt with C60 fullerene nanoparticle will allow to enhance the antitum
Autor:
Uwe Ritter, Yuriy Prylutskyy, Natalia Dziubenko, Volodymyr Rybalchenko, Tetyana S Herheliuk, O.V. Lynchak, H.M. Kuznietsova
Publikováno v:
BioImpacts, Vol 9, Iss 4, Pp 227-237 (2019)
BioImpacts : BI
BioImpacts : BI
Introduction: Oxidative stress has been suggested as the main trigger and pathological mechanism of toxic liver injury. Effects of powerful free radical scavenger С60 fullerene on rat liver injury and liver cells (HepG2 line) were aimed to be discov
Publikováno v:
Biotechnologia Acta, Vol 12, Iss 1, Pp 66-74 (2019)
Aim of the work was to investigate the suspended C60-fulleren effect on liver and pancreas state under intraperitoneal and intragastrial administration on rat experimental cholangitis model. Acute cholangitis was simulated by a single ingestion of ɑ
Autor:
O.V. Lynchak, H.M. Kuznietsova, I.V. Byelinska, Volodymyr Rybalchenko, Uwe Ritter, O. A. Kyzyma, Oleksandr I. Ivankov, Yu. I. Prylutskyy, N.V. Dziubenko, T.V. Rybalchenko
Publikováno v:
Materials Science and Engineering: C. 93:505-517
The application of pristine С 60 fullerene aqueous colloid solution (C 60 FAS; 0.5 mg/kg body weight) for rats experienced acute colitis, either intraperitoneally or intrarectally (1) restores the colonic mucosa healing and epithelial barrier integr
Publikováno v:
Reports of the National Academy of Sciences of Ukraine. :105-112