Výsledky vyhledávání - "O.C. Speelman"

Classification of clinical autofluorescence spectra of oral leukoplakia using an artificial neural network: a pilot study

Autor: H.J. van Staveren, Max J. H. Witjes, J.L.N. Roodenburg, O.C. Speelman, R.L.P. van Veen, W. M. Star

Publikováno v: Oral Oncology-European Journal of Cancer Part B, 36, 286-293. Pergamon Press Ltd.

The performance of an artificial neural network was evaluated as an alternative classification technique of autofluorescence spectra of oral leukoplakia, which may reflect the grade of tissue dysplasia. Twenty-two visible lesions of 21 patients suffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901f105dcbcf2fce593fe8deee62daf6
https://pure.eur.nl/en/publications/bba4563f-febe-4109-9cd5-7bb7bf03a49c

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In vivo detection of dysplastic tissue by Raman spectroscopy

Autor: Hajo A. Bruining, E. T. Marple, Henricus J. C. M. Sterenborg, J.L.N. Roodenburg, O.C. Speelman, Max J. H. Witjes, Gerwin J. Puppels, T. C. Bakker Schut

Publikováno v: Analytical Chemistry, 72(24), 6010-6018. AMER CHEMICAL SOC INC
Analytical chemistry, 72(24), 6010-6018. American Chemical Society
Analytical Chemistry, 72(24), 6010-6018. American Chemical Society

The detection of dysplasia and early cancer is important because of the improved survival rates associated with early treatment of cancer. Raman spectroscopy is sensitive to the changes in molecular composition and molecular conformation that occur i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c258b255c44f94328a1d7ff43f6d8c
https://research.rug.nl/en/publications/9e85c008-d1d2-42ac-929c-b68447897336

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Localisation and accumulation of a new carotenoporphyrin in two primary tumour models

Autor: W. M. Star, Devens Gust, Thomas A. Moore, J. T H M Van Den Akker, H J van Staveren, O.C. Speelman, Henricus J. C. M. Sterenborg, Ana L. Moore

Publikováno v: Journal of Photochemistry and Photobiology B-Biology, 54, 108-115. Elsevier
Journal of photochemistry and photobiology. B, Biology, 54(2-3), 108-115. Elsevier

We have investigated the tumour-localising properties and in vivo fluorescence kinetics of a hexamethoxylated carotenoporphyrin (CP6) in two primary tumour models: UV-B-induced early skin cancer in hairless mice and chemically induced mucosal dysplas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af386b162e8cbf3a601434bb15ef7558
https://pure.eur.nl/en/publications/e2f44149-1107-4e9b-8b35-4e01314ea35f

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Carotenoporphyrin Localization and Accumulation in (Pre-)Malignant Lesions as measured with in vivo Fluorescence Imaging and Spectroscopy

Autor: Jthm van den Akker, O.C. Speelman, W. M. Star, HS van Staveren, H.J.C.M. Sterenborg

Publikováno v: Biomedical Optics.

An important factor in successful treatment of cancer is the early detection of (pre-)malignant lesions.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d530c56405d499ca5f66ab8a4bae3b3a
https://doi.org/10.1364/bio.1999.bwa2

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In vivo photo-detection of chemically induced premalignant lesions and squamous cell carcinoma of the rat palatal mucosa

Autor: Max J. H. Witjes, P.G.J. Nikkels, J.M. Nauta, H. L. L. M. Van Leengoed, J.L.N. Roodenburg, O.C. Speelman, W. M. Star, Albert Vermey

Publikováno v: Journal of Photochemistry and Photobiology B-Biology, 39, 156-166. Elsevier

Photo-detection using in vivo fluorescence was studied for different stages of chemically induced premalignant lesions and squamous cell carcinoma (SCC) of the Wistar rat palatal mucosa. It was found that the epithelial dysplasia (numerically express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69a7a82f28a11902ae844c289247d3e
https://pure.eur.nl/en/publications/3b5b664e-9410-4310-8aea-7d3b2e11dcd4

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Fluorescence Imaging and Spectroscopy of Ethyl Nile Blue A in Animal Models of (Pre)malignancies¶

Autor: Willem M. Star, Max J. H. Witjes, Louis Cincotta, Hugo J. van Staveren, O.C. Speelman

Publikováno v: Photochemistry and Photobiology, 73(1), 32-38. Wiley-Blackwell

Discrimination between normal and premalignant tissues by fluorescence imaging and/or spectroscopy may be enhanced by a tumor-localizing fluorescent drug. Ethyl Nile Blue A (EtNBA), a dye with no phototoxic activity, was investigated for this purpose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f64c8ac2e8c7a3707a34e71475ccd3b
https://doi.org/10.1562/0031-8655(2001)073<0032:fiasoe>2.0.co

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