Zobrazeno 1 - 10
of 14
pro vyhledávání: '"O. Yu. Kravtsova"'
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 57-61 (2024)
GIZh-298 pharmacokinetics was studied in rats after different dosage regimens.The aim of this study was to study GIZh-298 pharmacokinetics after its multiple intragastric administration.Methods. The study was conducted on outbred male rats. The conce
Externí odkaz:
https://doaj.org/article/be8d424ff7b74361aeb67c69dfbf0a4b
Autor:
O. Yu. Kravtsova, D. A. Dvoryaninov, G. B. Kolyvanov, A. A. Litvin, O. G. Gribakina, V. P. Zherdev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 27-31 (2024)
The pharmacokinetics of a new antiparkinsonian drug ADK-1113 after single intravenous and intragastric administrations in mice at doses of 10 and 20 mg/kg was studied. The absolute bioavailability was 10.1–16.3 % that indicates on potential possibi
Externí odkaz:
https://doaj.org/article/e506aa073e4040589c58ace1ed60986e
Autor:
G. B. Kolyvanov, A. A. Litvin, P. O. Bochkov, O. Yu. Kravtsova, O. G. Gribakina, P. Yu. Povarnina, V. P. Zherdev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 4, Pp 41-47 (2024)
Relevance. To introduce the GK-2 compound into clinical practice, it is necessary to conduct a preclinical study of its pharmacokinetics, in particular, the distribution of the studied drug in organs and tissues. The aim is to study the tissue availa
Externí odkaz:
https://doaj.org/article/5c7f5e8406504c54875dd3d0b9f6d420
Autor:
O. Yu. Kravtsova, O. G. Gribakina, G. B. Kolyvanov, A. A. Litvin, P. O. Bochkov, P. Yu. Povarnina, V. P. Zherdev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 12-18 (2023)
The pharmacokinetics of dimeric dipeptide mimetic of nerve growth factor GC-2 in the rat blood plasma after different routes of administration was studied. The drug was administered at dose of 150 mg/kg by single and repeatedly. After single intrave
Externí odkaz:
https://doaj.org/article/e8c497f291f7473f9c19ee94ffb123e4
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 37-45 (2022)
GIZh-298 is a new derivative of 4-phenylpyrrolidone with anticonvulsant and nootropic effects. A selective and sensitive HPLC-MS technique for the quantitative determination of GIZh-298 in rat blood plasma has been developed and validated. The linear
Externí odkaz:
https://doaj.org/article/562d748deb1d4666a79264303ed54545
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 17-22 (2022)
The distribution kinetics of a compound with cardioprotective activity, N1-(2,3,4-trimethoxybenzyl)-N2-{2-[(2,3,4-trimethoxybenzyl)amino] ethyl}-1,2-ethanediamine (ALM-802) in rat tissues and organs after single intragastric administration at a dose
Externí odkaz:
https://doaj.org/article/5ca71ab2babf4e178b06dbb833a39cc2
Autor:
A. L. Podol'ko, K. N. Kolyasnikova, P. O. Bochkov, R. V. Shevchenko, V. P. Zherdev, A. A. Litvin, G. B. Kolyvanov, O. Yu. Kravtsova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 172:618-621
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6859ca6e205679e4ff12686bdf0206
https://doi.org/10.47056/0365-9615-2021-172-11-618-621
https://doi.org/10.47056/0365-9615-2021-172-11-618-621
Autor:
G B, Kolyvanov, P O, Bochkov, A A, Litvin, R V, Shevchenko, A L, Podol'ko, O Yu, Kravtsova, K N, Kolyasnikova, V P, Zherdev
Publikováno v:
Bulletin of experimental biology and medicine. 172(5)
Metabolism of a new neuroprotector GZK-111 (N-phenylacetylglycyl-L-proline ethyl ester) in rat blood plasma was studied by HPLC-mass spectrometry. Four biotransformation products were identified. It is concluded that the main ways of GZK-111 biotrans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c1746e09ca3e65cc6c7f715da1805f2
https://pubmed.ncbi.nlm.nih.gov/35352249
https://pubmed.ncbi.nlm.nih.gov/35352249
Autor:
I. I. Miroshnichenko, O. Yu. Kravtsova
Publikováno v:
Pharmaceutical Chemistry Journal. 44:628-631
A highly sensitive and reproducible method for assay of fluvoxamine in biological samples using HPLC combined with various detection methods (spectrophotometry and tandem mass spectrometry) was developed. These methods were completely interchangeable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::649a948334e5d0889ef8c38ce02fbf65
https://doi.org/10.1007/s11094-011-0533-y
https://doi.org/10.1007/s11094-011-0533-y
Autor:
Sariev Ak, B. A. Badyshtov, V. P. Zherdev, O. Yu. Kravtsova, M. N. Levina, A. A. Litvin, Sergey B. Seredenin, G. B. Kolyvanov
Publikováno v:
Pharmaceutical Chemistry Journal. 40:588-590
Pharmacokinetics of sydnocarb upon the joint administration with ladasten was investigated in rats. Being introduced in this combination, sydnocarb was detected in the blood plasma for a longer time, showed higher values of the distribution coefficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e57c5ec7413f671f3e59914b40e081a8
https://doi.org/10.1007/s11094-006-0199-z
https://doi.org/10.1007/s11094-006-0199-z