Zobrazeno 1 - 10
of 17
pro vyhledávání: '"O. Yu. Klyuchivska"'
Publikováno v:
Біологічні студії, Vol 16, Iss 2, Pp 3-18 (2022)
Background. Various cationic polymers have been proposed for use as carriers of genetic materials in biotechnology and biomedicine. The poly(2-dimethylamino)ethyl-methacrylate (poly(DMAEMA)) demonstrated high transfection efficiency and low cytotoxic
Externí odkaz:
https://doaj.org/article/c2790050ae014ce195c69bfbfc11f560
Autor:
N. S. Finiuk, O. Yu. Klyuchivska, I. I. Ivasechko, N. E. Mitina, Yu. V. Ostapiuk, M. D. Obushak, O. S. Zaichenko, A. M. Babsky, R. S. Stoika
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 3, Pp 39-51 (2021)
Thiazole derivatives are perspective antitumor compounds characterized by a broad range of bioactivity, while polymeric carriers are widely used to enhance the efficiency of biological action of drugs, improve their biocompatibility and water solubil
Externí odkaz:
https://doaj.org/article/ec798388f6fa40e09972e029bd7eb46e
Autor:
N. S. Finiuk, O. Yu. Klyuchivska, H. M. Kuznietsova, S. P. Vashchuk, V. K. Rybalchenko, R. S. Stoika
Publikováno v:
Біологічні студії, Vol 14, Iss 4, Pp 3-14 (2020)
Background. The heterocyclic scaffolds are in the list of key structural blocks used at synthesis of novel biologically active compounds. Materials and Methods. The present study addressed the evaluation of the mechanisms of the DNA damaging and p
Externí odkaz:
https://doaj.org/article/af695640bb6048c3b302d7ba5d9b579b
Autor:
N. S. Finiuk, I. I. Ivasechko, O. Yu. Klyuchivska, H. M. Kuznietsova, V. K. Rybalchenko, R. S. Stoika
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 4, Pp 55-62 (2020)
Development of chemical compounds capable to supress tumor progression is a perspective strategy of cancer treatment. Heterocyclic compounds possess a broad spectrum of biological activities, including anticancer one. According to the previous result
Externí odkaz:
https://doaj.org/article/3b3160873d374497b540a908e21cd4e2
Autor:
N. S. Finiuk, I. I. Ivasechko, O. Yu. Klyuchivska, Yu. V. Ostapiuk, V. P. Hreniukh, Ya. R. Shalai, V. S. Matiychuk, M. D. Obushak, A. M. Babsky, R. S. Stoika
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 2, Pp 29-39 (2019)
Derivatives of 2-amino-5-benzylthiazole are heterocyclic pharmacophores that exhibit different pharmacological activities including anticancer action. The mechanisms of such action of these compounds are not clear. The aim of the present study was to
Externí odkaz:
https://doaj.org/article/27ac830802be498180465ac22808e03e
Publikováno v:
Biotechnologia Acta, Vol 8, Iss 2, Pp 58-68 (2015)
The aim of this investigation was to study chemical composition and biological effects of substances present in methanol extract of dried basidiocarps of Lactarius quetus and L. volemus and the action of substances of milky juice isolated from these
Externí odkaz:
https://doaj.org/article/b013ee79ae714a5ba79770a14afad29a
Autor:
N. M. Boiko, O. Yu. Klyuchivska, L. I. Коbylinska, D. Ya. Havrylyuk, A. O. Ryabtseva, N. Ye. Mitina, R. B. Lesyk, O. S. Zаichenko, R. S. Stoika
Publikováno v:
Biotechnologia Acta, Vol 8, Iss 1, Pp 39-48 (2015)
A nanoscale polymeric carrier was used for delivery of novel anticancer compounds – 4-tiazolidinone derivatives – to tumor cells of different lines. It was found that such way of delivery of the above mentioned compounds to target cells significa
Externí odkaz:
https://doaj.org/article/b26f9f4f109348758735d23cf6e44049
Autor:
Nataliya Mitina, O. S. Zaichenko, Mykola D. Obushak, Yu. V. Ostapiuk, O. Yu. Klyuchivska, Andriy M. Babsky, Rostyslav Stoika, I. I. Ivasechko, N. S. Finiuk
Publikováno v:
Ukrainian Biochemical Journal, Vol 93, Iss 3, Pp 39-51 (2021)
Thiazole derivatives are perspective antitumor compounds characterized by a broad range of bioactivity, while polymeric carriers are widely used to enhance the efficiency of biological action of drugs, improve their biocompatibility and water solubil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9231d6e7bf9869757430d5b1623a51
https://doi.org/10.15407/ubj93.02.039
https://doi.org/10.15407/ubj93.02.039
Autor:
S. P. Vashchuk, O. Yu. Klyuchivska, Volodymyr Rybalchenko, H.M. Kuznietsova, N. S. Finiuk, Rostyslav Stoika
Publikováno v:
Біологічні студії, Vol 14, Iss 4, Pp 3-14 (2020)
Background. The heterocyclic scaffolds are in the list of key structural blocks used at synthesis of novel biologically active compounds. Materials and Methods. The present study addressed the evaluation of the mechanisms of the DNA damaging and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3d5e32b68c16364afcda4c28e08001
http://publications.lnu.edu.ua/journals/index.php/biology/article/view/1178
http://publications.lnu.edu.ua/journals/index.php/biology/article/view/1178
Autor:
Nataliya Mitina, Lesya Kobylinska, Alexander Zaichenko, Roman Lesyk, O. Yu. Klyuchivska, Rostyslav Stoika, N. R. Skorohyd, Borys Zimenkovsky
Aim. To study an anticancer activity and to measure cytological and enzymatic indicators of general toxicity of 4-thiazolidinone-based compounds (Les-3288, Les-3833) in the NK/Ly lymphoma grafted to BALB/C mice. Methods. BALB/C mice were implanted wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac27a3683ae89fd8a064a7875d4d383d
http://dspace.nbuv.gov.ua/handle/123456789/154393
http://dspace.nbuv.gov.ua/handle/123456789/154393
