Výsledky vyhledávání - "O. V. Vetrovoy"

The Role of Lipids in Implementing Specific Functions in the Central Nervous System

Autor: O. V. Galkina, Natalia Eschenko, O. V. Vetrovoy

Publikováno v: Russian Journal of Bioorganic Chemistry. 47:1004-1013

The review is devoted to the features of lipid composition of the brain and the description of specific functions of lipids in ensuring the activity of the nervous system. Lipids are an extremely heterogeneous group of molecules, which leads to a wid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b61eb666e16a7243c511b2f681a1de5
https://doi.org/10.1134/s1068162021050253

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Transcription Factor HIF1 Negatively Regulates the Content of Glucose-6-Phosphate Dehydrogenase in HEK293T Cells

Autor: O. V. Vetrovoy, Peter Nimiritsky, E. I. Tyul’kova, Elena Rybnikova

Publikováno v: Cell and Tissue Biology. 15:181-188

The identification of new targets for the regulation of hypoxia-induced transcriptional factor HIF1 is an urgent problem in cellular and molecular biology. The cobalt chloride (CoCl2) inductor of HIF1 accumulation and topotecan blocker of its transla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::107a0f07f6faaeb2703147e9dfac5267
https://doi.org/10.1134/s1990519x21020127

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Prenatal Hypoxia Induces Premature Aging Accompanied by Impaired Function of the Glutamatergic System in Rat Hippocampus

Autor: O. V. Vetrovoy, V. A. Stratilov, Peter Nimiritsky, Pavel I. Makarevich, E. I. Tyul’kova

Publikováno v: Neurochemical Research. 46:550-563

Prenatal hypoxia is among leading causes of progressive brain pathologies in postnatal life. This study aimed to analyze the characteristics of the hippocampal glutamatergic system and behavior of rats in early (2 weeks), adult (3 months) and advance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5985b372d19c909aa901e86c293508
https://doi.org/10.1007/s11064-020-03191-z

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Prenatal Stress as a Factor of the Development of Addictive States

Autor: O. V. Vetrovoy, E. I. Tyul’kova, V. A. Stratilov

Publikováno v: Journal of Evolutionary Biochemistry and Physiology. 56:471-490

Nowadays, the issue of the role of non-hereditary factors in the formation of addictive states arouses great interest. The review analyzes the results of clinical and fundamental studies of the molecular and cellular basis of addiction caused by stre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f997e701e22b5f9561f70963c443574
https://doi.org/10.1134/s0022093020060010

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The Content and Activity of Hypoxia-Inducible Factor HIF1α Increased in the Hippocampus of Newborn Rats That Were Subjected to Prenatal Hypoxia on Days 14–16 of Embryogenesis

Autor: Peter Nimiritsky, E. I. Tyul’kova, O. V. Vetrovoy, Elena Rybnikova

Publikováno v: Neurochemical Journal. 14:286-289

—Western blot and quantitative real-time PCR were used to study the content of the regulatory alpha subunit of hypoxia-inducible factor-1 (HIF1α), and the mRNA content of the HIF1-regulated genes lactate dehydrogenase A (ldha) and glucose-6-phosph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::971acf79d32b70427d1b33c7f787b062
https://doi.org/10.1134/s1819712420030125

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Peculiarities of DNA and Histone H3 Methylation in the Hippocampus and Neocortex of Rats Subjected to Pathological Treatments during the Prenatal Period

Autor: V. A. Stratilov, O. V. Vetrovoy, E. I. Tyul’kova, L. A. Vataeva, V. S. Barysheva

Publikováno v: Neurochemical Journal. 14:64-72

—Stress during pregnancy can cause the structural and functional changes in the fetal brain, which subsequently lead to the formation of various neuropsychiatric diseases, including attention deficit hyperactivity disorder, depression, schizophreni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::860a47ff91d4d06affc7d5012042908a
https://doi.org/10.1134/s1819712420010195

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The Pattern of DNA and Histone H3 Methylation in Rat Brain in Response to Severe Hypobaric Hypoxia and Hypoxic Postconditioning

Autor: M. O. Samoilov, O. V. Vetrovoy, E. I. Tyul’kova, K. A. Baranova, V. A. Stratilov

Publikováno v: Cell and Tissue Biology. 14:36-42

Methylation of histone H3 Lys4 (meН3К4) and Lys9 (meН3К9), as well as DNA methylation (meDNA), was investigated in rat hippocampal and neocortex neurons in an original model of severe hypobaric hypoxia (SHH) and hypoxic postconditioning (PostC).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66a32c59ae9520800d7f75ecbad71f89
https://doi.org/10.1134/s1990519x20010101

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Pharmacological HIF1 Inhibition Eliminates Downregulation of the Pentose Phosphate Pathway and Prevents Neuronal Apoptosis in Rat Hippocampus Caused by Severe Hypoxia

Autor: O. V. Vetrovoy, Ekaterina Lomert, Peter Nimiritsky, O. V. Galkina, Andrey Lyanguzov, E. I. Tyul’kova, Natalia Eschenko, Elena Rybnikova, K. V. Sarieva

Publikováno v: Journal of Molecular Neuroscience. 70:635-646

The pentose phosphate pathway (PPP) of glucose metabolism in the brain serves as a primary source of NADPH which in turn plays a crucial role in multiple cellular processes, including maintenance of redox homeostasis and antioxidant defense. In our m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076d62fe39552888554eba0183b14610
https://doi.org/10.1007/s12031-019-01469-8

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