Výsledky vyhledávání - "O. V. Rokhlin"

[Study of the antigenic structure of human immunoglobulin lambda-chain using monoclonal antibodies]

Autor: E L, Arsen'eva, G T, Bogacheva, A, Solomon, D, Weiss, A R, Ibragimov, O V, Rokhlin

Publikováno v: Molekuliarnaia biologiia. 24(1)

Nine monoclonals against human Ig lambda chains were produced, 4 antibodies react with C-domain, 5--with V-domain of the lambda chain. Anti-C lambda domain antibodies recognize not less than 3 epitopes and one of them is expressed only on the isolate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d2fb08ec1eb16bedcdfafb087060f403
https://pubmed.ncbi.nlm.nih.gov/1693412

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Elisa test system with monoclonal antibodies to human IgG4 for the detection of allergen-specific antibodies in pollinosis

Autor: G. T. Bogacheva, Arsen'eva El, Chernokhvostova Ev, Kotova Ts, O. V. Rokhlin, O. I. Atovmyan

Publikováno v: Bulletin of Experimental Biology and Medicine. 108:1589-1592

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e3c4e46f059556849f72b226a01e533
https://doi.org/10.1007/bf00839696

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Natural autoantibodies of neonatal rats detectable by the hybridoma technique

Autor: O. V. Rokhlin, L. Z. Yakubov, A. V. Sakharova, N. V. Romanova, V. V. Cherepakhin

Publikováno v: Bulletin of Experimental Biology and Medicine. 106:1144-1146

Neonatal rat hybridomas were tested for natural autoantibodies (NAA) production, using different screening procedures. NAA were discovered in 35% of immunoglobulins producing hybridomas. Radioimmunoassay (RIA) on brain and liver homogenates and immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98b54264e940f6e9598c2278cbfa2b26
https://doi.org/10.1007/bf00840383

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[Immunochemical properties of tryptophanyl-tRNA synthetase and its fragments]

Autor: S F, Beresten', V Sh, Sheĭnker, O V, Rokhlin

Publikováno v: Molekuliarnaia biologiia. 12(6)

The interaction between beef pancreas tryptophanyl-tRNA synthetase and its fragments produced after limited proteolysis, with IgG fraction of antiserum and with Fab fragment of IgG has been studied. Both the intact antibodies and Fab fragments inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d14cdc898fba7e1bfbc325e9b7dea86c
https://pubmed.ncbi.nlm.nih.gov/85256

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[Immunochemical comparison of tryptophanyl-tRNA-synthetases]

Autor: V Sh, Sheĭnker, O O, Favorova, O V, Rokhlin

Publikováno v: Molekuliarnaia biologiia. 12(3)

A fraction of immunoglobulins was isolated from the sera of rabbit immunised by a homogeneous beef pancreas tryptophanyl-tRNA-synthetase (TRSase). The IgG fraction was shown to inhibit the enzymatic activity during aminoacylation of yeast tRNATrp and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2b9ed3cfa7de94a8fe3a0272606822c9
https://pubmed.ncbi.nlm.nih.gov/78439

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[Analysis of the frequency of allelic exclusion of immunoglobulin light chain genes and molecular characteristics of immunoglobulins secreted by hybridomas with expression of both allelic genes]

Autor: V V, Cherepakhin, L Z, Iakubov, A R, Ibragimov, T I, Vengerova, O V, Rokhlin

Publikováno v: Molekuliarnaia biologiia. 20(6)

The investigation of 750 B-lymphocyte hybridoma clones obtained by fusion of mouse myeloma and newborn heterozygous Igk-la/Igk-1b rat splenocytes has revealed that 9,8% of Ig kappa-chain genes are rearranged productively. Seventeen hybridomas secrete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5c95cfc2d67d388fd97a8f050747e2be
https://pubmed.ncbi.nlm.nih.gov/3100944

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[Allelic exclusion in hybridomas. II. Characteristics of the synthesis of 2 allelic variants of rat immunoglobulin kappa-chains in a cloned hybridoma line]

Autor: V V, Cherepakhin, O V, Rokhlin

Publikováno v: Molekuliarnaia biologiia. 21(1)

Production of Igk-1a and Igk-1b allelic variants of rat Ig kappa-chains in hybridoma clone 4C2 was studied. Gel-filtration of the culture fluid demonstrates that the cells secrete isolated L-chains in monomeric and dimeric form. Different L-chain all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::663d01ec2866569a6099e7d8acfb3997
https://pubmed.ncbi.nlm.nih.gov/3106787

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Allotypes of light chains of rat immunoglobulins

Autor: R S, Nezlin, O V, Rokhlin, T I, Vengerova

Publikováno v: Annales d'immunologie. (1-2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be7e0da825cf6429ada8ebf09a1f1758
https://pubmed.ncbi.nlm.nih.gov/4142571

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[Switch in the synthesis of IgM--IgG antibodies. I. Ratio of allelic variants of light rat immunoglobulin chains in antilactoside antibodies of different classes]

Autor: O V, Rokhlin

Publikováno v: Molekuliarnaia biologiia. 10(1)

Ratio of allelic variants was studied of the rat immunoglobulin light chains in IgM and IgG fractions of anti-lactoside antibodies isolated from the sera of immune heterozygous rats (WAGXMSU)F1 and (AugustXMSU)F1. For MSU rat strain, RL1 allelic vari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::208e771ad9b0b85c3a7e4263609dea16
https://pubmed.ncbi.nlm.nih.gov/822282

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