Zobrazeno 1 - 10
of 46
pro vyhledávání: '"O. V. Podobed"'
Autor:
M. V. Pokrovskaya, Nikolay N. Sokolov, Vadim S. Pokrovsky, D. D. Zhdanov, D. V. Grishin, O. V. Podobed, Yu A Gladilina, S. S. Aleksandrova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 165:461-464
Mutant homologues of small chemotactic and DNA-binding proteins from thermophilic bacteria Thermotoga petrophila RKU-1 and Thermotoga naphthophila were obtained. These proteins can be expressed in the recombinant form in E. coli cells. A wide range o
Autor:
D. D. Zhdanov, S. S. Aleksandrova, Yu. A. Gladilina, Nikolay N. Sokolov, D. V. Grishin, V. S. Orlova, M. V. Pokrovskaya, O. V. Podobed
Publikováno v:
Cell and Tissue Biology. 12:217-230
It is known that apoptotic endonuclease G (EndoG) induces alternative splicing (AS) of telomerase catalytic subunit TERT (telomerase reverse transcriptase) mRNA and inhibits telomerase activity in tumor cells and activated human T cells. The aim of t
Autor:
Nikolay N. Sokolov, A. L. Milyushkina, D. V. Grishin, O. V. Podobed, M. A. Vigovskiy, D. D. Zhdanov, M. V. Pokrovskaya, Ju. A. Gladilina, Vadim S. Pokrovsky, S. S. Aleksandrova
Publikováno v:
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry. 12:143-150
In the work a recombinant chemotaxis protein CheW from Thermotoga petrophila RKU-1 (TpeCheW) and its mutant homolog (TpeCheW-mut) were created. It was shown that, despite the low homology with CheW prototypes from intestinal bacteria, these proteins
Autor:
V. L. Kovalenko, O. V. Podobed
Publikováno v:
CLINICAL AND EXPERIMENTAL MORPHOLOGY. 26:61-64
Autor:
O. V. Podobed, S. S. Aleksandrova, V. S. Orlova, Nikolay N. Sokolov, Yu. A. Gladilina, D. D. Zhdanov, D. V. Grishin, M. V. Pokrovskaya
Publikováno v:
Tsitologiya. 60:104-115
Autor:
D. V. Grishin, Yu A Gladilina, Nikolay N. Sokolov, D. D. Zhdanov, V. S. Pokrovskii, S. S. Aleksandrova, M. V. Pokrovskaya, O. V. Podobed
Publikováno v:
Applied Biochemistry and Microbiology. 53:688-698
The study of the poultry needs in basic nutrients allowed the development of a scheme for obtaining feed polypeptides (“polypeptide cassettes”) enriched with L-amino acids, which are necessary for the metabolism of birds. The amino acid and nucle
Autor:
G. Yu. Lomakina, S. S. Aleksandrova, O. V. Podobed, D. V. Grishin, N. S. Melik-Nubarov, I. D. Grozdova, O. Yu. Abakumova, M. V. Pokrovskaya, Nikolay N. Sokolov, V. S. Pokrovski
Publikováno v:
Applied Biochemistry and Microbiology. 53:165-172
N-hydroxysuccinimide ester of monomethoxy polyethylene glycol hemisuccinate was synthesized. It acylated amino groups in a molecule of recombinant L-asparaginase from Erwinia carotovora. A method of L-asparaginase modification by the obtained activat
Autor:
D. V. Grishin, M. V. Pokrovskaya, O. V. Podobed, Nikolay N. Sokolov, S. S. Aleksandrova, Vadim S. Pokrovsky, Ju. A. Gladilina
Publikováno v:
Biomeditsinskaya Khimiya. 63:124-131
The construction of proteins and peptides with desired properties, including resistance to high temperatures, as well as optimization of their amino acid composition, is an important and complex task, which attracts much attention in various branches
Publikováno v:
Moscow University Chemistry Bulletin. 71:122-126
The ChitoPEGylation method, which is a novel approach to regulating the catalytic properties of enzymes that is based on the formation of a covalent conjugate of an enzyme with branched copolymers of chitosan, has been developed. The efficiency of th
Autor:
O. V. Podobed, Alexander I. Archakov, M. V. Pokrovskaya, N. S. Melik-Nubarov, Michael A. Eldarov, S. S. Aleksandrova, Nikolay N. Sokolov, Elena V. Kudryashova, D. V. Grishin, O. Yu. Abakumova
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 9:325-338
For more than 40 years L-asparaginases are used in combined therapy of acute lymphoblastic leukemia in children and the range of tumors sensitive to these enzymes constantly extends. This review summarizes results of studies aimed at creation of new