Zobrazeno 1 - 10
of 58
pro vyhledávání: '"O. V. Akopova"'
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 6, Pp 63-76 (2020)
Permeability transition pore (mPTP) opening was studied under energized and deenergized conditions in rat liver mitochondria, and the effect of membrane depolarization on mPTP activity was evaluated. To assess mPTP activity, cyclosporine-sensitive sw
Externí odkaz:
https://doaj.org/article/3e5fdd1ef9b94dacb5e7a804affdf26d
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 5, Pp 5-14 (2020)
The aspects of ATP-sensitive K+ transport regulation by mitochondrial K+,ATP-sensitive (mKATP) channels openers are important for understanding the properties of these channels. The effect of KATP channels openers (KCOs) diazoxide and pinacidil on AT
Externí odkaz:
https://doaj.org/article/57e6dd42a26c44098fe0f54945d28820
Autor:
M. M. Batyushin, I. V. Derevyankina, M. Z. Gasanov, O. V. Akopova, K. I. Babiyan, Y. N. Boychenko, N. V. Vasilchenko, T. A. Gabysyan, S. Ch. Gayboryan, I. S. Golovatenko, N. M. Demkova, D. O. Dmitriev, E. V. Kirtava, O. L. Kotyankova, G. V. Ludanova, S. A. Lyashenko, A. E. Malichina, O. I. Poroshenko, A. V. Svechnikova, I. Y. Sidorov, E. V. Solyannikova, I. D. Tascheyan, E. A. Heygetyan, S. E. Evruyan
Publikováno v:
Рациональная фармакотерапия в кардиологии, Vol 3, Iss 2, Pp 38-42 (2015)
Aim. To increase in efficacy of antihypertensive therapy in patients with refractory arterial hypertension (HT).Material and methods. Patients with refractory HT were revealed during first month of program. The causes of refractory HT were analyzed.
Externí odkaz:
https://doaj.org/article/09344e2cd0e84d418b341b2901cc41b5
Publikováno v:
The Ukrainian Biochemical Journal, Vol 86, Iss 2, Pp 26-40 (2014)
The effect of mitochondrial ATP-dependent K+-channel (K+ATP-channel) opener diazoxide (DZ) on transmembrane potassium exchange and reactive oxygen species (ROS) formation under the opening of mitochondrial permeability transition pore (MPTP) was stud
Externí odkaz:
https://doaj.org/article/6c673ef62ae04fcd8cde3603d8889862
Publikováno v:
The Ukrainian Biochemical Journal, Vol 86, Iss 1, Pp 21-28 (2014)
The effect of potassium on state 4 respiration (substrate oxidation in the absence of ADP) was investigated. It was shown that potential-dependent potassium uptake in the brain mitochondria results in mitochondrial depolarization. Taking into account
Externí odkaz:
https://doaj.org/article/790647f5afa74704bf6b75453dca7574
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 3, Pp 38-51 (2013)
The effect of mitochondrial ATP-dependent K+-channel (K+АТР-channel) opener diazoxide (DZ) on the oxygen consumption, functional state and the opening of cyclosporine-sensitive pore in the rat liver mitochondria has been studied. It has been estab
Externí odkaz:
https://doaj.org/article/b95ebf1786d64025ae46760ab6ff9e26
Autor:
O. V. Akopova, V. I. Nosar, L. I. Kolchinskaya, I. N. Mankovska, M. K. Malysheva, V. F. Sagach
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 1, Pp 33-41 (2013)
The effect of potential-dependent potassium uptake on the transmembrane potential difference (ΔΨm) in rat brain mitochondria has been studied. It was shown that in potassium concentration range of 0-120 mM the potential-dependent K+-uptake into m
Externí odkaz:
https://doaj.org/article/b447a961d5674318a4556d32bd00eee5
Autor:
L. I. Kolchinskaya, A. N. Smirnov Kolchinskaya, L. V. Bratus Kolchinskaya, O. V. Akopova, V. I. Nosar Kolchinskaya
Publikováno v:
Ukrainian Biochemical Journal, Vol 92, Iss 5, Pp 5-14 (2020)
The aspects of ATP-sensitive K+ transport regulation by mitochondrial K+,ATP-sensitive (mKATP) channels openers are important for understanding the properties of these channels. The effect of KATP channels openers (KCOs) diazoxide and pinacidil on AT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c41dd4baa1ea221a04e7832d9495dd5
https://doi.org/10.15407/ubj92.05.005
https://doi.org/10.15407/ubj92.05.005
The modulation of mKATP channel activity is known to have a great impact on energy metabolism in a living organism. The aim of this work was to study the impact of mKATP channels opening on the physical endurance in the rats subject to compulsory swi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a1fcbdc8cfa80958c782cd060f609ab
https://doi.org/10.9734/bpi/nicb/v2/11158d
https://doi.org/10.9734/bpi/nicb/v2/11158d
Diazoxide affects mitochondrial bioenergetics by the opening of mKATP channel on submicromolar scale
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-14 (2020)
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology
Background Cytoprotection afforded by mitochondrial ATP-sensitive K+-channel (mKATP-channel) opener diazoxide (DZ) largely depends on the activation of potassium cycle with eventual modulation of mitochondrial functions and ROS production. However, g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07175413b3cf109094b5fa4f2d69617a
https://doi.org/10.1186/s12860-020-00275-0
https://doi.org/10.1186/s12860-020-00275-0