Zobrazeno 1 - 7
of 7
pro vyhledávání: '"O. T. Dejesus"'
Autor:
D, Murali, T E, Barnhart, N T, Vandehey, B T, Christian, R J, Nickles, A K, Converse, J A, Larson, J E, Holden, M L, Schneider, O T, Dejesus
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 72
A simple synthesis of the dopamine transporter ligand [(18)F]FECNT with high radiochemical yield and short synthesis time, suitable for routine production is reported. Reaction of 2β-carbomethoxy-3β-(4-chlorophenyl)nortropane with [(18)F]2-fluoroet
Publikováno v:
Synapse (New York, N.Y.). 39(1)
The effect of aging on aromatic L-amino acid decarboxylase (AAAD) activity in rhesus monkey striatum was assessed in vivo using PET imaging. Two analogs of L-DOPA, 6-fluoro-m-tyrosine (FMT) and 6-fluoro-L-DOPA (FDOPA), were used to image rhesus monke
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(11)
This article presents dosimetry based on the measurement of fluoro-DOPA activity in major tissues and in the bladder contents in humans after oral pretreatment with 100 mg carbidopa.Bladder activity was measured continuously by external probe and cal
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(4)
Fluorinated m-tyrosine analogs were evaluated as PET imaging agents and compared with 6-fluoroDOPA in the visualization of dopamine nerve terminals.The three m-tyrosine analogs, 6-[18F]fluoro-L-m-tyrosine (6-FMT), 2-[18F]fluoro-L-m-tyrosine (2-FMT) a
Publikováno v:
Annals of neurology.
An in vivo study of the binding of the neuroleptic drugs spiroperidol and bromospiroperidol has indicated a large amount of specific binding to the dopamine-rich caudate nuclei of the murine brain. We have tested the applicability of the simple therm
Publikováno v:
Life sciences. 35(21)
The binding of spiroperidol and bromospiroperidol, in vivo, was studied over a wide range of drug dosages. It was found that while spiroperidol and bromospiroperidol bind selectively in vivo to tissues known to be high in dopamine receptor binding si
Publikováno v:
Cancer research. 48(20)
While theoretically feasible, estrogen receptor (ER)-directed radiotherapy of hormone-dependent cancers has not been realized because no ER-seeking ligand with an appropriate radiotoxic potential has been identified. Since an appropriate nuclide is a