Provider adherence to clinical care recommendations for infants and children who died in seven low- and middle-income countries in the Child Health and Mortality Prevention Surveillance (CHAMPS) networkResearch in context

Autor: Chris A. Rees, Kitiezo Aggrey Igunza, Zachary J. Madewell, Victor Akelo, Dickens Onyango, Shams El Arifeen, Emily S. Gurley, Mohammad Zahid Hossain, Afruna Rahman, Muntasir Alam, J. Anthony G. Scott, Nega Assefa, Lola Madrid, Anteneh Belachew, Haleluya Leulseged, Karen L. Kotloff, Samba O. Sow, Milagritos D. Tapia, Adama Mamby Keita, Diakaridia Sidibe, Antonio Sitoe, Rosauro Varo, Sara Ajanovic, Quique Bassat, Inácio Mandomando, Beth A. Tippett Barr, Ikechukwu Ogbuanu, Carrie Jo Cain, Ima-Abasi Bassey, Ronita Luke, Khadija Gassama, Shabir Madhi, Ziyaad Dangor, Sana Mahtab, Sithembiso Velaphi, Jeanie du Toit, Portia C. Mutevedzi, Dianna M. Blau, Robert F. Breiman, Cynthia G. Whitney, Fatima Solomon, Gillian Sorour, Hennie Lombaard, Jeannette Wadula, Karen Petersen, Martin Hale, Nelesh P. Govender, Peter J. Swart, Sanjay G. Lala, Richard Chawana, Yasmin Adam, Amy Wise, Ashleigh Fritz, Nellie Myburgh, Pedzisai Ndagurwa, Cleopas Hwinya, Sanwarul Bari, Shahana Parveen, Mohammed Kamal, A.S.M. Nawshad Uddin Ahmed, Mahbubul Hoque, Saria Tasnim, Ferdousi Islam, Farida Ariuman, Mohammad Mosiur Rahman, Ferdousi Begum, K. Zaman, Mustafizur Rahman, Dilruba Ahmed, Meerjady Sabrina Flora, Tahmina Shirin, Mahbubur Rahman, Joseph Oundo, Alexander M. Ibrahim, Fikremelekot Temesgen, Tadesse Gure, Addisu Alemu, Melisachew Mulatu Yeshi, Mahlet Abayneh Gizaw, Stian Orlien, Solomon Ali, Peter Otieno, Peter Nyamthimba Onyango, Janet Agaya, Richard Oliech, Joyce Akinyi Were, Dickson Gethi, Sammy Khagayi, George Aol, Thomas Misore, Harun Owuor, Christopher Mugah, Bernard Oluoch, Christine Ochola, Sharon M. Tennant, Carol L. Greene, Ashka Mehta, J. Kristie Johnson, Brigitte Gaume, Rima Koka, Karen D. Fairchild, Diakaridia Kone, Doh Sanogo, Uma U. Onwuchekwa, Nana Kourouma, Seydou Sissoko, Cheick Bougadari Traore, Jane Juma, Kounandji Diarra, Awa Traore, Tiéman Diarra, Kiranpreet Chawla, Tacilta Nhampossa, Zara Manhique, Sibone Mocumbi, Clara Menéndez, Khátia Munguambe, Ariel Nhacolo, Maria Maixenchs, Andrew Moseray, Fatmata Bintu Tarawally, Martin Seppeh, Ronald Mash, Julius Ojulong, Babatunde Duduyemi, James Bunn, Alim Swaray-Deen, Joseph Bangura, Amara Jambai, Margaret Mannah, Okokon Ita, Cornell Chukwuegbo, Sulaiman Sannoh, Princewill Nwajiobi, Dickens Kowuor, Erick Kaluma, Oluseyi Balogun, Solomon Samura, Samuel Pratt, Francis Moses, Tom Sesay, James Squire, Joseph Kamanda Sesay, Osman Kaykay, Binyam Halu, Hailemariam Legesse, Francis Smart, Sartie Kenneh, Soter Ameh, Jana Ritter, Tais Wilson, Jonas Winchell, Jakob Witherbee, Navit T. Salzberg, Jeffrey P. Koplan, Margaret Basket, Ashutosh Wadhwa, Kyu Han Lee, Valentine Wanga, Roosecelis Martines, Shamta Warang, Maureen Diaz, Jessica Waller, Shailesh Nair, Lucy Liu, Courtney Bursuc, Kristin LaHatte, Sarah Raymer, John Blevins, Solveig Argeseanu, Kurt Vyas, Manu Bhandari

Publikováno v: EClinicalMedicine, Vol 63, Iss , Pp 102198- (2023)

Summary: Background: Most childhood deaths globally are considered preventable through high-quality clinical care, which includes adherence to clinical care recommendations. Our objective was to describe adherence to World Health Organization recomme

Externí odkaz: https://doaj.org/article/7bbde38ed56a44c89b6d96f1be3aa920

Antenatal, intrapartum and infant azithromycin to prevent stillbirths and infant deaths: study protocol for SANTE, a 2×2 factorial randomised controlled trial in Mali

Autor: Lawrence H Moulton, Robert L Goldenberg, Samba O Sow, Dilruba Nasrin, Fadima Cheick Haidara, Amanda J Driscoll, Karen L Kotloff, Milagritos D Tapia, Emily L Deichsel, Ousmane S Samake, Tiecoura Bocoum, Jason A Bailey, Meagan C Fitzpatrick, Mamoudou Kodio, Uma Onwuchekwa, Allison M Shaffer

Publikováno v: BMJ Open, Vol 13, Iss 8 (2023)

Introduction In high mortality settings, prophylactic azithromycin has been shown to improve birth weight and gestational age at birth when administered antenatally, to reduce the incidence of neonatal infections when administered intrapartum, and to

Externí odkaz: https://doaj.org/article/0c26cb293a814829918b1e18acf87d9b

Spatiotemporal variation in risk of Shigella infection in childhood: a global risk mapping and prediction model using individual participant data

Autor: Hamada S Badr, PhD, Josh M Colston, PhD, Nhat-Lan H Nguyen, BA, Yen Ting Chen, MD, Eleanor Burnett, MPH, Syed Asad Ali, MPH, Ajit Rayamajhi, MD, Syed M Satter, MPH, Nguyen Van Trang, PhD, Daniel Eibach, PD, Ralf Krumkamp, DrPH, Jürgen May, MD, Ayola Akim Adegnika, PhD, Gédéon Prince Manouana, PhD, Peter Gottfried Kremsner, MD, Roma Chilengi, MSc, Luiza Hatyoka, PhD, Amanda K Debes, PhD, Jerome Ateudjieu, PhD, Abu S G Faruque, MPH, M Jahangir Hossain, MSc, Suman Kanungo, PhD, Karen L Kotloff, MD, Inácio Mandomando, PhD, M Imran Nisar, PhD, Richard Omore, PhD, Samba O Sow, MSc, Anita K M Zaidi, SM, Nathalie Lambrecht, PhD, Bright Adu, PhD, Nicola Page, MPH, James A Platts-Mills, MD, Cesar Mavacala Freitas, MD, Tuula Pelkonen, PhD, Per Ashorn, PhD, Kenneth Maleta, PhD, Tahmeed Ahmed, PhD, Pascal Bessong, PhD, Zulfiqar A Bhutta, PhD, Carl Mason, MD, Estomih Mduma, PhD, Maribel P Olortegui, MPH, Pablo Peñataro Yori, MPH, Aldo A M Lima, PhD, Gagandeep Kang, PhD, Jean Humphrey, ScD, Robert Ntozini, MPH, Andrew J Prendergast, DPhil, Kazuhisa Okada, PhD, Warawan Wongboot, PhD, Nina Langeland, PhD, Sabrina J Moyo, PhD, James Gaensbauer, MD, Mario Melgar, MD, Matthew Freeman, PhD, Anna N Chard, MPH, Vonethalom Thongpaseuth, MD, Eric Houpt, MD, Benjamin F Zaitchik, PhD, Margaret N Kosek, MD

Publikováno v: The Lancet Global Health, Vol 11, Iss 3, Pp e373-e384 (2023)

Summary: Background: Diarrhoeal disease is a leading cause of childhood illness and death globally, and Shigella is a major aetiological contributor for which a vaccine might soon be available. The primary objective of this study was to model the spa

Externí odkaz: https://doaj.org/article/bf7cee71ef0a40cfb55dc0350ac997ee

Causes of death identified in neonates enrolled through Child Health and Mortality Prevention Surveillance (CHAMPS), December 2016 -December 2021.

Autor: Sana Mahtab, Shabir A Madhi, Vicky L Baillie, Toyah Els, Bukiwe Nana Thwala, Dickens Onyango, Beth A Tippet-Barr, Victor Akelo, Kitiezo Aggrey Igunza, Richard Omore, Shams El Arifeen, Emily S Gurley, Muntasir Alam, Atique Iqbal Chowdhury, Afruna Rahman, Quique Bassat, Inacio Mandomando, Sara Ajanovic, Antonio Sitoe, Rosauro Varo, Samba O Sow, Karen L Kotloff, Henry Badji, Milagritos D Tapia, Cheick B Traore, Ikechukwu U Ogbuanu, James Bunn, Ronita Luke, Sulaiman Sannoh, Alim Swarray-Deen, Nega Assefa, J Anthony G Scott, Lola Madrid, Dadi Marami, Surafel Fentaw, Maureen H Diaz, Roosecelis B Martines, Robert F Breiman, Zachary J Madewell, Dianna M Blau, Cynthia G Whitney, CHAMPS Consortium

Publikováno v: PLOS Global Public Health, Vol 3, Iss 3, p e0001612 (2023)

Each year, 2.4 million children die within their first month of life. Child Health and Mortality Prevention Surveillance (CHAMPS) established in 7 countries aims to generate accurate data on why such deaths occur and inform prevention strategies. Neo

Externí odkaz: https://doaj.org/article/597ac256dd7f4d9aaca13eca5fead733

Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries

Autor: Moses Badio, Edouard Lhomme, Mark Kieh, Abdoul Habib Beavogui, Stephen B. Kennedy, Seydou Doumbia, Bailah Leigh, Samba O. Sow, Alpha Diallo, Daniela Fusco, Matthew Kirchoff, Monique Termote, Renaud Vatrinet, Deborah Wentworth, Helène Esperou, H. Clifford Lane, Jerome Pierson, Deborah Watson-Jones, Céline Roy, Eric D’Ortenzio, Brian Greenwood, Genevieve Chêne, Laura Richert, James D. Neaton, Yazdan Yazdanpanah, the PREVAC study team

Publikováno v: Trials, Vol 22, Iss 1, Pp 1-15 (2021)

Abstract Introduction The Ebola virus disease (EVD) outbreak in 2014–2016 in West Africa was the largest on record and provided an opportunity for large clinical trials and accelerated efforts to develop an effective and safe preventative vaccine.

Externí odkaz: https://doaj.org/article/a164f3bab6ae47f8b2c9a625b606ebd6