Výsledky vyhledávání - "O. S. de Leeuw"

Generation of a recombinant chimeric Newcastle disease virus vaccine that allows serological differentiation between vaccinated and infected animals

Autor: Ben Peeters, Guus Koch, Gielkens Arnoud Leonard Josef, I. Verstegen, O. S. de Leeuw

Publikováno v: Vaccine, 19, 1616-1627
Vaccine 19 (2001)

Using a recently developed reverse genetics system, we have generated a recombinant Newcastle disease virus (NDV) vaccine in which the gene encoding the hemagglutinin-neuraminidase (HN) has been replaced by a hybrid HN gene consisting of the cytoplas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e1b572589dbae15447e906f51bcf01
https://doi.org/10.1016/s0264-410x(00)00419-9

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Complete nucleotide sequence of Newcastle disease virus: evidence for the existence of a new genus within the subfamily Paramyxovirinae

Autor: Ben Peeters, O. S. de Leeuw

Publikováno v: Journal of General Virology, 80, 131-136
Journal of General Virology 80 (1999)

We have completely sequenced the genome of Newcastle disease virus (NDV) vaccine strain LaSota. The sequences of the 3'- and 5'-terminal ends of the RNA genome were determined by sequencing cDNA fragments generated by rapid amplification of cDNA ends

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e991ba3d658bb95c970e1b4906848ca5
https://doi.org/10.1099/0022-1317-80-1-131

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Cloning and DNA sequence analysis of a Serpulina (Treponema) hyodysenteriae gene encoding a periplasmic flagellar sheath protein

Autor: M. B. H. Koopman, Johannes G. Kusters, O. S. de Leeuw, B. A. M. Van Der Zeijst

Publikováno v: Infection and Immunity. 60:2920-2925

A Serpulina (Treponema) hyodysenteriae expression library was constructed in vector lambda ZAP and screened with a polyclonal antiserum raised against S. hyodysenteriae periplasmic flagella. A single immunoreactive plaque was chosen for further analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19abe85da02ee8bfecdf2d74da38266
https://doi.org/10.1128/iai.60.7.2920-2925.1992

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Suitability of PER.C6 (R) cells to generate epidemic and pandemic influenza vaccine strains by reverse genetics

Autor: Jaap Goudsmit, Ronald Vogels, L. Hartgroves, C. Ophorst, Lisette A. H. M. Cornelissen, Isabelle Legastelois, Menzo J. E. Havenga, Wendy S. Barclay, Wouter Koudstaal, David Zuijdgeest, O. S. de Leeuw, Jerome Custers, Martijn Sieuwerts, E.A. de Boer-Luijtze

Publikováno v: Vaccine 27 (2009) 19
Vaccine, 27(19), 2588-2593
Vaccine, 27(19), 2588-2593. Elsevier BV
Vaccine, 19, 27, 2588-2593

Reverse genetics, the generation of influenza viruses from cDNA, presents a rapid method for creating vaccine strains. The technique necessitates the use of cultured cells. Due to technical and regulatory requirements, the choice of cell lines for pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3805d651c0471e3bb9d7e9ede9cbce63
https://research.wur.nl/en/publications/suitability-of-perc6-r-cells-to-generate-epidemic-and-pandemic-in

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Recombinant Newcastle disease virus (NDV) with inserted gene coding for GM-CSF as a new vector for cancer immunogene therapy

Autor: Volker Schirrmacher, Markus Janke, Annette Arnold, R Moorman, Ben Peeters, O. S. de Leeuw, Philippe Fournier

Publikováno v: Gene Therapy 14 (2007)
Gene Therapy, 14, 1639-1649

This is the first report describing recombinant (rec) Newcastle disease virus (NDV) as vector for gene therapy of cancer. The gene encoding granulocyte/macrophage colony-stimulating factor (GM-CSF) was inserted as an additional transcription unit at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53f9f6e25cc81a4ab33d953edcdbb5d
https://pubmed.ncbi.nlm.nih.gov/17914407

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Genome replication of Newcastle disease virus: involvement of the rule-of-six

Autor: O. S. de Leeuw, Ben Peeters, Gielkens Arnoud Leonard Josef, Y. K. Gruijthuijsen

Publikováno v: Archives of virology. 145(9)

We examined replication of Newcastle disease virus (NDV) by using minigenomes consisting of the 3′ leader and 5′ trailer regions of NDV flanking a reporter gene encoding secreted placental alkaline phosphatase (SEAP). Negative-sense minigenome RN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d0592ed648a078c465e17aabe7bb79
https://pubmed.ncbi.nlm.nih.gov/11043944

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Molecular analysis of a flagellar core protein gene of Serpulina (Treponema) hyodysenteriae

Autor: O. S. de Leeuw, B. A. M. Van Der Zeijst, M. B. H. Koopman, Johannes G. Kusters, E. Baats

Publikováno v: Journal of general microbiology. 139(8)

SUMMARY: The flaB2 gene encoding a protein located in the core of the periplasmic flagella of Serpulina hyodysenteriae was cloned and sequenced. The FlaB2 protein consists of 285 amino acids and has a calculated molecular mass of 31.1 kDa. Southern b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89087238a39d6716eea4d647f1f53ff
https://pubmed.ncbi.nlm.nih.gov/8409912

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