Zobrazeno 1 - 10
of 29
pro vyhledávání: '"O. S. Zaichenko"'
Publikováno v:
Біологічні студії, Vol 16, Iss 4, Pp 19-32 (2022)
Background. Drug delivery systems (DDS) have demonstrated a significant ability to overcome many of the challenges associated with the delivery of hydrophobic chemotherapeutic compounds to tumor tissues. However, hepatotoxicity and suppression of the
Externí odkaz:
https://doaj.org/article/82f707fcfcde49b1a1370aea6bb87fbf
Publikováno v:
Біологічні студії, Vol 15, Iss 4, Pp 37-48 (2021)
Background. Previous studies have shown a pronounced cytotoxic effect of thiazole derivatives in combination with polymeric carriers on tumor cells. At the same time, the derivatives were not cytotoxic against non-cancerous cells in vitro. It was sho
Externí odkaz:
https://doaj.org/article/1af81c10b43a4fac9a0bd8353fa537a7
Autor:
M. V. Popovych, Ya. R. Shalai, V. P. Hreniukh, O. R. Kulachkovskyy, S. M. Mandzynets, N. E. Mitina, O. S. Zaichenko, A. M. Babsky
Publikováno v:
Біологічні студії, Vol 15, Iss 2, Pp 15-24 (2021)
Background. A pronounced cytotoxic action of the thiazole derivatives complexed with polymeric carriers on tumor cells in vitro was reported earlier, while no cytotoxicity of these compounds was detected toward noncancerous cells. It was found that t
Externí odkaz:
https://doaj.org/article/311c245da19a4933901364fa4d4cb27a
Autor:
N. S. Finiuk, O. Yu. Klyuchivska, I. I. Ivasechko, N. E. Mitina, Yu. V. Ostapiuk, M. D. Obushak, O. S. Zaichenko, A. M. Babsky, R. S. Stoika
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 3, Pp 39-51 (2021)
Thiazole derivatives are perspective antitumor compounds characterized by a broad range of bioactivity, while polymeric carriers are widely used to enhance the efficiency of biological action of drugs, improve their biocompatibility and water solubil
Externí odkaz:
https://doaj.org/article/ec798388f6fa40e09972e029bd7eb46e
Autor:
N. S. Finiuk, J. V. Senkiv, A. O. Riabtseva, N. Y. Mitina, N. I. Molochii, M. O. Kitsera, S. S. Avdieiev, O. S. Zaichenko, R. S. Stoika
Publikováno v:
The Ukrainian Biochemical Journal, Vol 88, Iss SI01, Pp 87-98 (2016)
Malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) occur more frequently than other types of primary central nervous system tumors, having a combined incidence of 5–8/100,000 population. Even with aggressive treatment using surg
Externí odkaz:
https://doaj.org/article/e5a2d5c105e54972939d0b8693137085
Publikováno v:
Біологічні студії, Vol 7, Iss 2, Pp 15-26 (2013)
Rapid development of new nanomaterials and nanotechnologies is accompanied by significant achievements in various fields of medicine, industry and precise technology, as well as by undesirable effects on human health and environment. Our studies were
Externí odkaz:
https://doaj.org/article/ee0ffebe1a9f407faea30666109ed02a
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 3, Pp 69-73 (2013)
Adjuvant properties of the polymer containing acrylic acid, glycidyl methacrylate, triethylene glycol methacrylate and butyl acrylate have been established. Antibodies to ovalbumin and bovine serum albumin in the blood of mice were revealed using d
Externí odkaz:
https://doaj.org/article/ce7a0bbe55f7471f8c8e7ea778931424
Autor:
H. I. Falfushynska, L. L. Gnatyshyna, O. O. Turta, O. B. Stoliar, N. E. Mitina, O. S. Zaichenko, R. S. Stoika
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 3, Pp 52-61 (2013)
The effect of metal-nanocomposites (Me-NC) of cobalt and zinc (Co- and Zn-NC, correspondingly) synthecized on the basis of vinylpyrrolidone (PS) on the metal-accumulative proteins with antioxidant potential metallothioneins (MT) in crucian carp (Cara
Externí odkaz:
https://doaj.org/article/7bfb350683a5440ba406ca88d01e282e
Autor:
Yu. V. Senkiv, P. Heffeter, A. O. Riabtseva, N. M. Boiko, O. S. Zaichenko, N. Ye. Mitina, W. Berger, R. S. Stoika
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 2, Pp 33-44 (2013)
Development of novel nanoscale functionalized carriers is nowadays one of the most urgent problems in cancer treatment. The aim of our study was to compare the antineoplastic effect of free doxorubicin and its complex with a nanoscale polymeric car
Externí odkaz:
https://doaj.org/article/2891e2b3a7d440a492aedb7729a57ab8
Autor:
Yu. V. Senkiv, A. R. Ryabtseva, P. Heffeter, N. M. Boiko, E. A. Shlyakhtina, N. E. Mitina, W. Berger, O. S. Zaichenko, R. S. Stoika
Publikováno v:
Біологічні студії, Vol 6, Iss 2, Pp 5-16 (2012)
Application of special systems for drug delivery into target cells might be useful for overcoming several problems in treatment of dangerous diseases. These are: consequences of nonspecific negative effects of drugs towards healthy cells, low sensiti
Externí odkaz:
https://doaj.org/article/f29a047589114239a5da056afed1c65e