Enhanced Fe(II)-artemisinin-mediated chemodynamic therapy with efficient Fe(III)/Fe(II) conversion circulation for cancer treatment.

Autor: Xiao Xu, Yun Wang, Dan Yan, Chunling Ren, Yuqian Cai, Shanting Liao, Lingyi Kong, Chao Han

Publikováno v: Biomaterials Science (2047-4830); 11/21/2024, Vol. 12 Issue 22, p5856-5869, 14p

Sulfonamide based pyrimidine derivatives combating Plasmodium parasite by inhibiting falcipains-2 and falcipains-3 as antimalarial agents.

Autor: Rahman, Abdur, Anjum, Shazia, Bhatt, Jaimin D., Dixit, Bharat C., Singh, Anju, khan, Sabiha, Fatima, Sadaf, Patel, Tarosh S., Hoda, Nasimul

Publikováno v: RSC Advances; 2024, Vol. 14 Issue 34, p24725-24740, 16p

Alterations of Kiss 1 receptor, GnRH receptor and nuclear receptors of the hypothalamopituitary- ovarian axis following low dose bisphenol-A exposure in Wistar rats.

Autor: Kadir, Eniola Risikat¹ kadir.re@unilorin.edu.ng, Imam, Aminu¹, Olajide, Olayemi Joseph^1,2, Ajao, Moyosore Saliu¹

Publikováno v: Anatomy & Cell Biology. Jun2021, Vol. 54 Issue 2, p212-224. 13p.

Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4.

Autor: Ashton TD; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Calic PPS; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Dans MG; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Kang Ooi Z; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia., Zhou Q; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia., Loi K; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Jarman KE; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Palandri J; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Qiu D; Research School of Biology, Australian National University, Canberra, 2601, Australia., Lehane AM; Research School of Biology, Australian National University, Canberra, 2601, Australia., Maity B; TCG Lifesciences, Kolkata, West Bengal, 700091, India., De N; TCG Lifesciences, Kolkata, West Bengal, 700091, India., Famodimu MT; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Delves MJ; Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Mao EY; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia., Gancheva MR; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia., Wilson DW; Research Centre for Infectious Diseases, School of Biological Sciences, University of Adelaide, Adelaide, 5005, Australia., Chowdury M; School of Medicine, Deakin University, Waurn Ponds, Victoria, 3216, Australia.; Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Victoria, 3216, Australia., de Koning-Ward TF; School of Medicine, Deakin University, Waurn Ponds, Victoria, 3216, Australia.; Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Victoria, 3216, Australia., Baud D; MMV Medicines for Malaria Venture, ICC, Route de Pré-Bois 20, 1215, Geneva, Switzerland., Brand S; MMV Medicines for Malaria Venture, ICC, Route de Pré-Bois 20, 1215, Geneva, Switzerland., Jackson PF; Emerging Science & Innovation, Discovery Sciences, Janssen R&D LLC, La Jolla, California, 92121, USA., Cowman AF; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia., Sleebs BE; Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3010, Victoria, Australia.

Publikováno v: ChemMedChem [ChemMedChem] 2024 Aug 30, pp. e202400549. Date of Electronic Publication: 2024 Aug 30.

A Water‐Soluble Polymer‐Lumefantrine Conjugate for the Intravenous Treatment of Severe Malaria.

Autor: Matshe, William M.R., Tshweu, Lesego L., Mvango, Sindisiwe, Cele, Zamani E.D., Chetty, Avashnee S., Pilcher, Lynne A., Famuyide, Ibukun M., McGaw, Lyndy J., Taylor, Dale, Gibhard, Liezl, Basarab, Gregory S., Balogun, Mohammed O.

Publikováno v: Macromolecular Bioscience; May2023, Vol. 23 Issue 5, p1-12, 12p