Zobrazeno 1 - 10
of 17
pro vyhledávání: '"O. L. Voronova"'
Autor:
V. I. Konenkov, M. A. Korolev, A. A. Churin, O. L. Voronova, O. V. Neupokoeva, L. N. Rachkovskaya, A. V. Shurlygina, M. V. Robinson, A. A. Kotlyarova, T. V. Popova, E. E. Rachkovskiy, P. G. Madonov, A. Yu. Letyagin
Publikováno v:
Сибирский научный медицинский журнал, Vol 39, Iss 5, Pp 62-67 (2019)
Aim of the study was to investigate the possible mutagenic properties of a new drug based on a lithium-containing substance – a complex of lithium citrate, polymethylsiloxane and aluminum oxide. Material and methods. Methods for testing mutagenicit
Externí odkaz:
https://doaj.org/article/d8d9d8b90c8a411881ce0d282633270b
Autor:
O. V. Neupokoeva, E. P. Fedorova, L. A. Sandrikina, M. V. Filonova, A. A. Churin, L. A. Stavrova, O. L. Voronova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 169:43-47
Paclitaxel in a single MTD of 40 mg/kg caused chromosome aberrations and genome changes (polyploidy) in the bone marrow cells of mice early and 3 months after the injection. The quantity of early precursors of erythropoiesis in the bone marrow decrea
Autor:
O. V. Neupokoeva, L. A. Ermolaeva, A. A. Churin, T. I. Fomina, O. L. Voronova, E. P. Fedorova, M. V. Filonova
Publikováno v:
Russian journal of genetics : Applied research. 2017. Vol. 7, № 2. P. 191-194
The gene protection effects of the hairy transgenic root extract, obtained as a result of the transformation of Scutellaria baicalensis into Agrobacterium rhizogenes, were revealed on a model of paclitaxel induced genotoxicity in mouse bone marrow an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a8c76bee961379ecb9e9426741aaa3
http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000581892
http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000581892
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 78(11)
Gene protective properties of synthetic antioxidant thiophane and the extract of in vitro cultivated roots of Scutellaria baicalensis were studied on the model of Dr. melanogaster larvae genetic structure damage by drugs cisplatin and cyclophosphan (
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 76(12)
The effect of root extract of Baikal skullcap (Scutellaria baicalensis) cultivated in vitro, on the gene structure of CBA/CaLac mice bone marrow cells damaged by anticancer drugs paclitaxel and cisplatin has been studied. It is established that the r
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 73(10)
Beginning with the first hours of experiments, cisplatin evoked an increase of chromosomal aberrations in CBA/CaLac bone marrow cells. Significant increase of structural infringements of chromosomes due to chromatid breaks was revealed in metaphase p
Autor:
A M, Gur'ev, M B, Belousov, R R, Akhmedzhanov, M S, Iusubov, O L, Voronova, G V, Karpova, A A, Churin
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 73(8)
Mutagenic properties of water soluble polysaccharides (WSPS) extracted from Acorus calamus L. have been studied. Neither a single intravenous injection nor a course intraperitoneal introduction of WSPS in a dose of 1/2 LD50 to mice of the CBA/CaLac l
Autor:
O L, Voronova, O P, Rogozina, Yu L, Dugina, A V, Martyushev, O I, Epstein, A M, Dygai, E D, Goldberg
Publikováno v:
Bulletin of experimental biology and medicine. 135
Single and repeated administration of ultralow doses of antibodies to erythropoietin did not increase the count of aberrant metaphases in bone marrow cells of BALB/c mice and were not genotoxic for Drosophila melanogaster wing cells in the test of so
Autor:
A A, Churin, G V, Karpova, T I, Fomina, T V, Vetoshkina, T Iu, Dubskaia, O L, Voronova, V D, Filimonov, M L, Belianin, V Iu, Usov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 71(4)
We have carried out a preclinical toxicological investigation (acute toxicity evaluation) of Mangascan (0.5 M solution of manganese(II) - EDTA complex) and Pentamang (0.5 M solution of manganese(II) - DTPA complex), a new paramagnetic contrast agents
Autor:
G V, Karpov, T I, Fomina, O L, Voronova, E V, Abramova, E A, Timina, T Iu, Lamzina, L A, Ermolaeva, A V, Perova
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 70(4)
Paclitaxel (single intravenous injection in a maximum tolerated dose of 4.6 mg/kg) to white outbred rats causes bone marrow hypoplasia, increased granulocyte and erythroid cell mitosis (metaphase-anaphase transition), and moderate pancytopenia develo