Zobrazeno 1 - 10
of 17
pro vyhledávání: '"O. L. Runova"'
Autor:
Elvira M. Firova, Alexey V. Sokolov, Valeria A. Kostevich, O. L. Runova, Irina A. Churashova, N. P. Gorbunov, Vadim B. Vasilyev
Publikováno v:
Medical academic journal. 21:75-86
BACKGROUND: Myeloperoxidase (MPO), the enzyme of leukocytes, catalyzes the production of reactive halogen species, which can modify the structure of lipoproteins. Chlorination and nitration of tyrosine residues in apolipoprotein A-1 lead to the forma
Autor:
Alexej V. Sokolov, Vadim B. Vasilyev, O. L. Runova, I. V. Gorudko, Sergej N. Cherenkevich, Valeria A. Kostevich, Oleg M. Panasenko
Publikováno v:
Chemistry and Physics of Lipids. 180:72-80
One of the factors promoting oxidative/halogenating modification of low-density lipoproteins (LDL) is myeloperoxidase (MPO). We have shown previously that MPO binds to the LDL surfaces. The LDL–MPO complex is uncoupled in the presence of peptide EQ
Publikováno v:
Biophysics. 55:760-764
Experimental evidence has been obtained that mutations in the presenilin 1 (PS1) gene in familial Alzheimer’s disease can lead to the disturbance of cell adhesion in model cell cultures. It was shown that, in L fibroblasts of mice with stable expre
Autor:
O. L. Runova, E. I. Talalaeva, S. V. Sarantseva, A. L. Shwartsman, K. V. Solovyov, Michael P. Vitek
Publikováno v:
Biophysics. 53:550-554
A comparative study of growth cone morphology in cultured embryonic neurons derived from wild type PS 1(+/+) and knockout PS 1(-/-) mice has been performed. Growth cones from wild type PS 1(+/+) mice were well spread and usually formed radially conti
Autor:
E. T. Zakharova, K. V. Ageeva, Alexey V. Sokolov, Vadim B. Vasilyev, M. O. Pulina, O. L. Runova
Publikováno v:
Biochemistry (Moscow). 72:872-877
Proteins from leukocytes were investigated for their ability to interact with ceruloplasmin (Cp), a copper-containing glycoprotein of human plasma. Extract from leukocytes was subjected to affinity chromatography on Cp-Sepharose, after which proteins
Autor:
S. V. Sarantseva, Michael P. Vitek, O. L. Runova, Yu. A. Tatishcheva, E. I. Talalaeva, A. L. Schwartsman
Publikováno v:
Biophysics. 51:740-743
Most cases of early-onset familial Alzheimer’s disease are caused by mutations in the presenilin 1 gene. Nonetheless, the function of presenilin 1 are not yet completely understood. It was shown that endogenous presenilin 1, as well as the adhesion
Autor:
A. S. Susorova, E. T. Zakharova, N. I. Kolodkin, M. O. Pulina, Alexey V. Sokolov, Vadim B. Vasilyev, O. L. Runova
Publikováno v:
Biochemistry (Moscow). 71:160-166
The presence of a complex of the copper-containing protein ceruloplasmin (Cp) with lactoferrin (Lf) in breast milk (BM) is shown for the first time. In SDS-free polyacrylamide gel electrophoresis (PAGE), electrophoretic mobility of Cp in BM is lower
Publikováno v:
Bulletin of Experimental Biology and Medicine. 123:159-162
Two plasmids carrying the cDNA fragment of human low-density lipoprotein receptor coding for its ligand-binding domain are constructed. The ligand-binding domain of the receptor composed of fused and individual polypeptides is purified and characteri
Publikováno v:
Biofizika. 55(5)
Experimental evidence has been obtained that mutations in the presenilin 1 (PS1) gene in familial Alzheimer's disease can lead to the disturbance of cell adhesion in model cell cultures. It was shown that, in L fibroblasts of mice with stable express
Publikováno v:
Biofizika. 53(6)
A comparative study of growth cone morphology in cultured embryonic neurons derived from wild type PS 1(+/+) and knockout PS 1(-/-) mice has been performed. Growth cones from wild type PS 1(+/+) mice were well spread and usually formed radially conti