Zobrazeno 1 - 10
of 12
pro vyhledávání: '"O. I. Lukashov"'
Publikováno v:
Pharmaceutical Chemistry Journal. 54:46-48
Oxidation by HNO3 at atmospheric pressure of toluenes with electronegative substituents on the benzene ring was studied. A method enabling the corresponding benzoic acids to be obtained in high yields with minimal wastes was developed. The method cou
Publikováno v:
Pharmaceutical Chemistry Journal. 52:641-643
A new means of preparing phenazepam is proposed. The new manufacturing technology for phenazepam implements the general principles for medicinal substance quality by using synthesis conditions and schemes yielding compounds as pure as possible.
Publikováno v:
Pharmaceutical Chemistry Journal. 49:51-54
A simple and technologically convenient method for the preparation of 1,2,5-trimethylpiperidin-4-one, a key compound in the synthesis of the drug Promedol, was developed.
Autor:
O. I. Lukashov, I. N. Stan’kov, P. V. Kazakov, I. D. Derevyagina, O. T. Morozova, A. V. Sosnov, F. M. Semchenko, V. B. Kondrat’ev
Publikováno v:
Journal of Analytical Chemistry. 70:213-219
A method has been developed for the determination of 2-endo(6′-chloropyridin-3′-yl)-7-azabicyclo[2.2.1]heptane (epibatidine) and 2-endo(6′-chloropyridin-3′-yl)-7-azabicyclo[2.2.1]heptane-7-ol (epibatidine biomarker) in blood plasma at a level
Autor:
N. S. Mirzabekova, O. T. Morozova, I. D. Derevyagina, S. V. Gorelenko, P. V. Kazakov, O. I. Lukashov
Publikováno v:
Pharmaceutical Chemistry Journal. 50:185-187
Oxidative bromination of o-xylene with liquid bromine or hydrobromic acid in aqueous solution in the presence of an alkali-metal bromate as the oxidizing agent was studied. The proposed method allowed the amount of wastes to be reduced while maintain
Publikováno v:
Pharmaceutical Chemistry Journal. 47:437-441
A preparative-scale method was developed for the production of the analgesic epibatidine, yielding its endo and exo isomers with yields of 9.9% and 8.8% respectively.
Autor:
N. E. Kuz’mina, A. V. Morozov, N. A. Sokolova, N. S. Mirzabekova, P. V. Kazakov, O. I. Lukashov
Publikováno v:
Pharmaceutical Chemistry Journal. 46:245-248
A new commercially applicable method for the synthesis of the myorelaxant 1,3,5-tris-(2′-diethylbenzylammonioethyl)- 1,3,5-triazine-2,4,6-trione tribromide (isocyuronium bromide) is described.
Autor:
N. S. Mirzabekova, N. E. Kuz’mina, O. I. Lukashov, N. A. Sokolova, S. N. Golosov, P. V. Kazakov, T. G. Perlova, V. V. Potapova, V. A. Kheinman, G. B. Ivanova
Publikováno v:
Russian Journal of Organic Chemistry. 45:355-359
Autor:
G. B. Ivanova, N. S. Mirzabekova, N. E. Kuz’mina, S. N. Golosov, V. A. Kheinman, T. G. Perlova, P. V. Kazakov, O. I. Lukashov, V. V. Potapova, N. A. Sokolova
Publikováno v:
Russian Journal of Organic Chemistry. 44:1139-1149
A number of permethrin derivatives having various substituents (Me, Et, Pr, Ph, PhCH2, PhCH2CH2) in position 2 of the cyclopropane ring were synthesized and assayed for insecticidal activity against typhoid flies, rice weevils, and black bean aphid a
Publikováno v:
Journal of Structural Chemistry. 49:644-649
The spatial isomers of the new synthetic analogs of ethyl permithrinic ether and permethrin were investigated by NMR (1H, 13C, DEPT (distortionless enhancement by polarization transfer), COSY (correlation spectroscopy), CHCORR (heteronuclear (C, H) s