Overall Health, Daily Functioning, and Quality of Life in Acute Hepatic Porphyria Patients: ENVISION, a Phase 3 Global, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Autor: Eliane Sardh, Ulrich Stölzel, Gayle Ross, Daphne Vassiliou, Jerzy Windyga, Charles J. Parker, Amy Simon, Sioban Keel, Raili Kauppinen, Craig Penz, T. Lin, Janneke G. Langendonk, Yutaka Horie, Paolo Ventura, Penelope E. Stein, A. Sasapu, Bruce Ritchie, Bruce Wang, Aneta Ivanova, Laurent Gouya, Peter Stewart, John D. Phillips, Delia D'Avola, T. Nakahara, Manisha Balwani, Karl E. Anderson, D.M. Bissell, David C. Rees, P. Aguilera Peiro, Herbert L. Bonkovsky, Pauline Harper, Samuel M. Silver, Jeeyoung Oh, John J. Ko, Jiaan-Der Wang, O. Hother-Nielsen, M.J. Lee, Sushama Scalera

Publikováno v: Sardh, E, Gouya, L, Rees, D C, Stein, P, Stoelzel, U, Aguilera Peiro, P, Bissell, D M, Bonkovsky, H L, Keel, S, Parker, C, Phillips, J D, Silver, S, Windyga, J, D'Avola, D, Ross, G, Stewart, P, Ritchie, B, Oh, J, Harper, P, Wang, J D, Langendonk, J G, Ivanova, A, Horie, Y, Anderson, K E, Ventura, P, Kauppinen, R, Vassiliou, D, Wang, B, Hother-Nielsen, O, Nakahara, T, Lee, M J, Sasapu, A, Scalera, S, Lin, T, Penz, C, Simon, A, Ko, J & Balwani, M 2020, ' Overall Health, Daily Functioning, and Quality of Life in Acute Hepatic Porphyria Patients : ENVISION, a Phase 3 Global, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial ', Digestive and Liver Disease, vol. 52, no. Suppl. 1, pp. E35 . https://doi.org/10.1016/j.dld.2019.12.123

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3c86a09a54fd6ef507322b981490dd
https://doi.org/10.1016/j.dld.2019.12.123

Hyperglycaemia enhances renal magnesium excretion in type 1 diabetic patients

Autor: P. Skøtt, O. Hother-Nielsen, Niels Anders Klitgaard, P. H. Andersen, M. S. Djurhuus, Allan Vaag, H.-H. Parving

Publikováno v: Scandinavian journal of clinical and laboratory investigation. 60(5)

Magnesium depletion is a common feature of diabetes mellitus, apparently related to glycaemic control. The aim of the study was to investigate the isolated effect of hyperglycaemia upon renal magnesium excretion. Urinary magnesium excretion rates wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e153a9964d852ac6a10952e827451c7
https://pubmed.ncbi.nlm.nih.gov/11003260

On the determination of basal glucose production rate in patients with type 2 (non-insulin-dependent) diabetes mellitus using primed-continuous 3-3H-glucose infusion

Autor: H. Beck-Nielsen, O. Hother-Nielsen

Publikováno v: Diabetologia. 33(10)

Using primed-continuous 3-3H-glucose infusion, basal glucose production rate has been reported to be 140% higher than normal or almost normal in hyperglycaemic patients with Type 2 (non-insulin-dependent) diabetes mellitus. To determine whether these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdfaaa9d72babce28ecae9d62b6fa42d
https://pubmed.ncbi.nlm.nih.gov/2257997

Glucose uptake and pulsatile insulin infusion: euglycaemic clamp and [33H] glucose studies in healthy subjects

Autor: Hans Ørskov, H. Beck-Nielsen, Ole Schmitz, O. Hother Nielsen, Jon Arnfred

Publikováno v: Acta Endocrinologica. 113:559-563

To test the hypothesis that insulin has a greater effect on glucose metabolism when given as pulsatile than as continuous infusion, a 354-min euglycaemic clamp study was carried out in 8 healthy subjects. At random order soluble insulin was given int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259c50d5039f6b054d3feb9013a1ddb3
https://doi.org/10.1530/acta.0.1130559

Effect of bepridil on metabolic control and insulin secretion in diabetics

Autor: A. Høegholm, K. Lindvig, H. Kraemmer Nielsen, Christian N. S. Pedersen, E. Apoil, Lars Romer Krusell, Steen Elkjær Husted, O. Hother Nielsen

Publikováno v: European Journal of Clinical Pharmacology. 34:221-226

In a double-blind cross-over study bepridil 900 mg followed by 300 mg daily for 11 days was given to 37 insulin (Type I) or non-insulin (Type II)-dependent diabetic patients. It did not modify the metabolic control of the patients as levels of glucos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4593476a552dcc67f15f7ffff212976
https://doi.org/10.1007/bf00540947