Zobrazeno 1 - 10
of 651
pro vyhledávání: '"O. Hornykiewicz"'
Autor:
J. Blesa, C. Pifl, M.A. Sánchez-González, C. Juri, M.A. García-Cabezas, R. Adánez, E. Iglesias, M. Collantes, I. Peñuelas, J.J. Sánchez-Hernández, M.C. Rodríguez-Oroz, C. Avendaño, O. Hornykiewicz, C. Cavada, J.A. Obeso
Publikováno v:
Neurobiology of Disease, Vol 48, Iss 1, Pp 79-91 (2012)
Parkinson's disease (PD) is diagnosed when striatal dopamine (DA) loss exceeds a certain threshold and the cardinal motor features become apparent. The presymptomatic compensatory mechanisms underlying the lack of motor manifestations despite progres
Externí odkaz:
https://doaj.org/article/9692e153e7e5499f86109e3d7ad3e3d9
Publikováno v:
Neurology. 70:1403-1410
Background: Patients with Parkinson disease (PD) may be akinetic/rigid, be tremor dominant, or have comparable severity of these motor symptoms (classic). The pathophysiologic basis of different PD phenotypes is unknown. This study assessed pallidal
Autor:
O. Hornykiewicz
Publikováno v:
Amino Acids. 23:65-70
The article traces the development of research on the naturally occurring amino acid L-3,4-dihydroxyphenylalanine (L-dopa), from the first synthesis of its D,L racemate in 1911, and the isolation of its L-isomer from seedling of Vicia faba beans to t
Autor:
O. Hornykiewicz, Kathleen Shannak, H. B. Niznik, Mark Guttman, Stephen J. Kish, Lee-Cyn Ang, Julie M. Wilson, Allan I. Levey, Christian Pifl, Alex Rajput
Publikováno v:
Neurology. 47:718-726
To determine the extent that different dopamine (DA) neuronal markers provide similar estimates of striatal (caudate and putamen) DA nerve terminal loss in idiopathic Parkinson's disease (PD), we compared, in postmortem striatum of 12 patients with P
Autor:
Y Shimizu, Yoshiaki Furukawa, O. Hornykiewicz, Stephen J. Kish, Hirotaro Narabayashi, Alex Rajput, Hideo Mori, Y. Mizuno, T. Tagawa, M. Yokochi, Mitsunobu Shimadzu
Publikováno v:
Annals of Neurology. 39:609-617
Recently, mutations of the GTP-cyclohydrolase I (GTP-CH I) gene, which catalyzes the first step in the tetrahydrobiopterin (BH4) biosynthesis, were discovered in Japanese patients with hereditary progressive dystonia/dopa-responsive dystonia (HPD/DRD
Autor:
O, Hornykiewicz
Publikováno v:
Journal of neural transmission. Supplementum. (70)
This article gives a short historical account of the events and circumstances that led to the discovery of the occurrence of dopamine (DA) in the brain and its deficiency in Parkinson's disease (PD). Some important consequences, for both the basic sc
Autor:
O. Hornykiewicz
Publikováno v:
Parkinson’s Disease and Related Disorders ISBN: 9783211289273
This article gives a short historical account of the events and circumstances that led to the discovery of the occurrence of dopamine (DA) in the brain and its deficiency in Parkinson’s disease (PD). Some important consequences, for both the basic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee8e6dbc3a3bb918589fc790886cebf5
https://doi.org/10.1007/978-3-211-45295-0_3
https://doi.org/10.1007/978-3-211-45295-0_3
Autor:
O, Hornykiewicz
Publikováno v:
Wiener klinische Wochenschrift. 113(22)
Autor:
W, Birkmayer, O, Hornykiewicz
Publikováno v:
Wiener klinische Wochenschrift. 113(22)
Autor:
O, Hornykiewicz
Publikováno v:
Advances in neurology. 86