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of 225
pro vyhledávání: '"O. Holmberg"'
Autor:
Oliver J. Mainwaring, Holger Weishaupt, Miao Zhao, Gabriela Rosén, Anna Borgenvik, Laura Breinschmid, Annemieke D. Verbaan, Stacey Richardson, Dean Thompson, Steven C. Clifford, Rebecca M. Hill, Karl Annusver, Anders Sundström, Karl O. Holmberg, Maria Kasper, Sonja Hutter, Fredrik J. Swartling
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
CDKN2A loss and p53 mutations are rare in MYC-driven Group 3 medulloblastomas (MBs). Here the authors generated a transgenic mouse model of Group 3 MB by MYC overexpression and show that MYC suppresses ARF to drive tumorigenesis.
Externí odkaz:
https://doaj.org/article/15ce094130ad4d1185c37a3fd0a60446
Akademický článek
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Autor:
Florian A. Siebzehnrubl, Justin D. Lathia, Karin Forsberg-Nilsson, Karl O. Holmberg, Giulia Taraboletti, Giorgio Colombo, Thomas M. McIntyre, Rui Chen, Shilpa Rao, Tyler J. Alban, Gustavo Roversi, Defne Bayik, Daniel J. Silver, Jamie Pugh, Anja Kordowski, James S. Hale, Ana Jimenez-Pascual
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644cb9442560b9ce1b625487f9c10274
https://doi.org/10.1158/2159-8290.22532788
https://doi.org/10.1158/2159-8290.22532788
Autor:
Florian A. Siebzehnrubl, Justin D. Lathia, Karin Forsberg-Nilsson, Karl O. Holmberg, Giulia Taraboletti, Giorgio Colombo, Thomas M. McIntyre, Rui Chen, Shilpa Rao, Tyler J. Alban, Gustavo Roversi, Defne Bayik, Daniel J. Silver, Jamie Pugh, Anja Kordowski, James S. Hale, Ana Jimenez-Pascual
Glioblastomas (GBM) are lethal brain tumors where poor outcome is attributed to cellular heterogeneity, therapeutic resistance, and a highly infiltrative nature. These characteristics are preferentially linked to GBM cancer stem cells (GSC), but how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ee195325c66286e0cd3c966fbbb78a
https://doi.org/10.1158/2159-8290.c.6546835
https://doi.org/10.1158/2159-8290.c.6546835
Autor:
Florian A. Siebzehnrubl, Justin D. Lathia, Karin Forsberg-Nilsson, Karl O. Holmberg, Giulia Taraboletti, Giorgio Colombo, Thomas M. McIntyre, Rui Chen, Shilpa Rao, Tyler J. Alban, Gustavo Roversi, Defne Bayik, Daniel J. Silver, Jamie Pugh, Anja Kordowski, James S. Hale, Ana Jimenez-Pascual
Supplementary Figure S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ce4b4686f26e869f76a146d529c259
https://doi.org/10.1158/2159-8290.22532794
https://doi.org/10.1158/2159-8290.22532794
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Results of differential gene expression analysis between pre-GTS1 tumor cells treated for 48 hours with DMSO or Dox.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3aca2848676764a629f6b06758f371
https://doi.org/10.1158/0008-5472.22433309.v1
https://doi.org/10.1158/0008-5472.22433309.v1
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Supplementary figure 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1912492597cfade9206b22e304f40fbd
https://doi.org/10.1158/0008-5472.22433336
https://doi.org/10.1158/0008-5472.22433336
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22efa60c78744a2d1ee1b74fa2e6c10b
https://doi.org/10.1158/0008-5472.22433321.v1
https://doi.org/10.1158/0008-5472.22433321.v1
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Relapse is the leading cause of death in patients with medulloblastoma, the most common malignant pediatric brain tumor. A better understanding of the mechanisms underlying recurrence could lead to more effective therapies for targeting tumor relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b77886ca8f27c3b99dc19b07dfadb1
https://doi.org/10.1158/0008-5472.c.6514337.v1
https://doi.org/10.1158/0008-5472.c.6514337.v1
Akademický článek
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