Zobrazeno 1 - 10
of 25
pro vyhledávání: '"O. HUDKOVA"'
Autor:
I. HORAK, T. SKATERNA, O. HUDKOVA, N. LATYSHKO, O. KHUDIAKOVA, K. TOKARCHUK, I. KRYSIUK, T. KISHKO, L. KNOPFOV, Á L. DROBOT
Publikováno v:
Biotechnologia Acta, Vol 17, Iss 2, Pp 7-9 (2024)
Aim. This study is focused on a comprehensive overview of mechanisms and processes involved in the acquisition of cancer cell plasticity in a manner dependent on the adapter protein Ruk/CIN85 (in rodents, Ruk — regulator of ubiquitous kinase; in hu
Externí odkaz:
https://doaj.org/article/5675522d64d746cfb1832825a790bce6
Publikováno v:
The Ukrainian Biochemical Journal, Vol 94, Iss 1, Pp 23-32 (2022)
Amine oxidases are involved in the progression of many diseases and their complications, including renal failure, due to the generation of the three toxic metabolites (H2O2, aldehydes, and ammonia) in the course of biogenic amines oxidative deaminati
Externí odkaz:
https://doaj.org/article/0fbf9abbaa3746fd85844b0e0296cda2
Autor:
A. Yu. Zhyvolozhnyi, I. R. Horak, D. S. Geraschenko, M. O. Gomozkova, O. O. Hudkova, S. J. Vainio, A. A. Samoylenko, L. B. Drobot
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 6, Pp 46-54 (2021)
Extracellular vesicles (EVs) are secreted by most cell types under both physiological and pathological conditions and were proposed to be actively involved in intercellular communication. The mode of EVs action is dependent on their cargos compositio
Externí odkaz:
https://doaj.org/article/1879c6942b644715a5ee17c81c8e29f8
Publikováno v:
Biotechnologia Acta, Vol 16, Iss 2, Pp 42-43 (2023)
The aim of the present study was to find out the role of Ruk/CIN85 in modulation of activities/content of key enzymes/components of glycolysis and hydrogen peroxide using as a model human NSCLC MOR wild type and resistant to drugs MOR/0.2R cells. M
Externí odkaz:
https://doaj.org/article/dba8ed4a9a914cd1867fcd368692457b
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 5, Pp 72-81 (2021)
The pathogenesis of pulmonary fibrosis (PF) is accompanied by extracellular matrix (ECM) deposition, oxidative stress, and inflammation progression, as well as hyperactivation of amine oxidases (AOs), which contribute to disease manifestation. The pr
Externí odkaz:
https://doaj.org/article/621ee24ca556462c8eb2757b2cc2b331
Autor:
I. R. Horak, N. V. Latyshko, O. O. Hudkova, T. O. Kishko, O. V. Khudiakova, D. S. Gerashchenko, T. D. Skaterna, I. P. Krysiuk, S. G. Shandrenko, L. B. Drobot
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 4, Pp 24-34 (2020)
Excessive reactive oxygen species (ROS) production may lead to damage of cellular proteins, lipids and DNA, and cause cell death. Our previous findings demonstrated that increased level of adaptor protein Ruk/CIN85 contributes to breast cancer cells
Externí odkaz:
https://doaj.org/article/d39bb56abc58455395cdfd914ea7e1d2
Publikováno v:
Biotechnologia Acta, Vol 15, Iss 2, Pp 58-59 (2022)
Aim. To determine the role of Ruk/CIN85 in the control of breast adenocarcinoma cells metabolism, we performed systemic analysis of the activity levels/content of key enzymes/components of glycolysis and oxidative phosphorylation using as a model the
Externí odkaz:
https://doaj.org/article/327ddc41ed3940568b80109047e59afa
Autor:
I R, Horak, N V, Latyshko, O O, Hudkova, K O, Tokarchuk, T O, Kishko, O I, Yusova, L B, Drobot, A A, Tykhomyrov
Publikováno v:
Experimental oncology. 44(1)
Cell surface plasmin is involved in tumor growth and metastatic dissemination by regulating cancer cells adhesion, migration and invasion. Plasmin-induced cell detachment is accompanied by an increased rate of reactive oxygen species (ROS) generation
Autor:
M P, Dmytrenko, S H, Shandrenko, L M, Petrun', T O, Kishko, N V, Sylonova, N V, Latyshko, O O, Hudkova, V V, Sushkova
Publikováno v:
Ukrains'kyi biokhimichnyi zhurnal (1999 ). 82(4)
Subchronic administration of semicarbazide in the experiment with the rats was used to reduce the formaldehyde level in the organism in order to reveal the interaction between formaldehyde metabolism and biochemical parameters, which define the oxida
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