Zobrazeno 1 - 10
of 61
pro vyhledávání: '"O. H. Shaheen"'
Publikováno v:
Journal of molecular graphicsmodelling. 109
Targeting Polo-like kinase 1 (Plk1) by molecular inhibitors is being a promising approach for tumor therapy. Nevertheless, insufficient methodical analyses have been done to characterize the interactions inside the Plk1 binding pocket. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34f5c81cfcbe69f764e1c209842ad7a
https://pubmed.ncbi.nlm.nih.gov/34562852
https://pubmed.ncbi.nlm.nih.gov/34562852
Autor:
Lubna Swellmeen, Rand Shahin, Yaser Al-Qarar’h, Tahani Alwidyan, Iman Mansi, Nabil N. Al-Hashimi, O. H. Shaheen
Publikováno v:
Journal of molecular graphicsmodelling. 80
Targeting tropomycin kinase A (TrkA) by small molecule inhibitors is considered as a promising strategy for treating several human cancers. To achieve this goal, a ligand based QSAR model was applied using the Discovery studio 4.5 (DS 4.5). Hence, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31c6a1531d01c92b13ce70bb6d558f9
https://pubmed.ncbi.nlm.nih.gov/29454290
https://pubmed.ncbi.nlm.nih.gov/29454290
Publikováno v:
Bioorganicmedicinal chemistry. 25(17)
Over expression of Human phosphatidyl inositol mannoside kinases isoform 1 (Pim-1 kinase) has been reported in several leukemia and solid tumors. Our continuous interest to reveal the secrecies of the mysterious Pim-1 kinase binding pocket has led us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65597e1b9c02385e80959832bd460bb
https://pubmed.ncbi.nlm.nih.gov/28760531
https://pubmed.ncbi.nlm.nih.gov/28760531
Publikováno v:
Journal of computer-aided molecular design. 30(1)
Targeting Proviral integration-site of murine Moloney leukemia virus 1 kinase, hereafter called Pim-1 kinase, is a promising strategy for treating different kinds of human cancer. Headed for this a total list of 328 formerly reported Pim-1 kinase inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd3b089b5fcef1d3cf98a61d596313b
https://pubmed.ncbi.nlm.nih.gov/26685860
https://pubmed.ncbi.nlm.nih.gov/26685860
Publikováno v:
Future Science OA
The targeting of protein kinases has great future potential for the design of new drugs against cardiovascular diseases (CVDs). Enormous efforts have been made toward achieving this aim. Unfortunately, kinase inhibitors designed to treat CVDs have su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b88e565bcf296c2876b1e6fa8c3780
https://doi.org/10.4155/fsoa-2017-0010
https://doi.org/10.4155/fsoa-2017-0010
Autor:
O H, Shaheen
Publikováno v:
Proceedings of the Royal Society of Medicine. 61(11 Pt 1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5885acdf082c119de2c22bdc150bfdde
https://pubmed.ncbi.nlm.nih.gov/20919051
https://pubmed.ncbi.nlm.nih.gov/20919051
Autor:
O. H. Shaheen
Former otolaryngologist Guy's Hospital, London (b 1913; q Guy's Hospital 1938; MBE, MS, FRCS), d 27 December 2002.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f930190e280d959f17e311510ef6b7
https://europepmc.org/articles/PMC1125679/
https://europepmc.org/articles/PMC1125679/
Autor:
V L McAllister, M. Walker, E. Barden, P. G. Bevan, A. Valle, J. M Ferries, D. Munro, D. Levitt, D. W Melville, A. Mahoney, P. Young, B. Thom, A. Penkala, O H Shaheen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18e948acc85a85d91d6043cd7a7006c
https://europepmc.org/articles/PMC1113854/
https://europepmc.org/articles/PMC1113854/
Publikováno v:
The Journal of laryngology and otology. 111(1)
Vagal paraganglioma is a rare usually benign tumour of neural crest origin. The malignant form of this tumour i s very uncommon and the diagnosis is made on the basis of its clinical behaviour rather than its histological appearance. We report a case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f69f9c08defc8ff1edb11d94250c2a7
https://pubmed.ncbi.nlm.nih.gov/9292143
https://pubmed.ncbi.nlm.nih.gov/9292143
Publikováno v:
Journal of the Royal College of Surgeons of Edinburgh. 36(6)
Bilateral vocal cord paralysis is a rare but major complication of thyroid surgery. Since 1983, patients with bilateral cord paralysis have been managed in this department using the carbon dioxide laser. Six patients with bilateral cord paralysis sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27b5549b11397586ec9401d57a9c7a3a
https://pubmed.ncbi.nlm.nih.gov/1774705
https://pubmed.ncbi.nlm.nih.gov/1774705