Zobrazeno 1 - 10
of 40
pro vyhledávání: '"O. H. Samuli Ollila"'
Autor:
Ricky Nencini, Morgan L. G. Regnier, Sofia M. Backlund, Efstathia Mantzari, Cory D. Dunn, O. H. Samuli Ollila
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Peptides or proteins containing small biomolecular aggregates, such as micelles, bicelles, droplets and nanodiscs, are pivotal in many fields ranging from structural biology to pharmaceutics. Monitoring dynamics of such systems has been limi
Externí odkaz:
https://doaj.org/article/c8dc3e12ad604f0587b419eaee8f49c7
Autor:
Anne M. Kiirikki, Hanne S. Antila, Lara S. Bort, Pavel Buslaev, Fernando Favela-Rosales, Tiago Mendes Ferreira, Patrick F. J. Fuchs, Rebeca Garcia-Fandino, Ivan Gushchin, Batuhan Kav, Norbert Kučerka, Patrik Kula, Milla Kurki, Alexander Kuzmin, Anusha Lalitha, Fabio Lolicato, Jesper J. Madsen, Markus S. Miettinen, Cedric Mingham, Luca Monticelli, Ricky Nencini, Alexey M. Nesterenko, Thomas J. Piggot, Ángel Piñeiro, Nathalie Reuter, Suman Samantray, Fabián Suárez-Lestón, Reza Talandashti, O. H. Samuli Ollila
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Tools based on artificial intelligence (AI) are currently revolutionising many fields, yet their applications are often limited by the lack of suitable training data in programmatically accessible format. Here we propose an effective solutio
Externí odkaz:
https://doaj.org/article/acfa193917a24cbab8ffde269f7d7c0d
Autor:
Annika Ciragan, Sofia M. Backlund, Kornelia M. Mikula, Hannes M. Beyer, O. H. Samuli Ollila, Hideo Iwaï
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
The growing understanding of partially unfolded proteins increasingly points to their biological relevance in allosteric regulation, complex formation, and protein design. However, the structural characterization of disordered proteins remains challe
Externí odkaz:
https://doaj.org/article/fa9f4e0518ee43869f0fef3e5dc56c64
Autor:
Hannes M. Beyer, Salla I. Virtanen, A. Sesilja Aranko, Kornelia M. Mikula, George T. Lountos, Alexander Wlodawer, O. H. Samuli Ollila, Hideo Iwaï
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8367 (2020)
Protein splicing catalyzed by inteins utilizes many different combinations of amino-acid types at active sites. Inteins have been classified into three classes based on their characteristic sequences. We investigated the structural basis of the prote
Externí odkaz:
https://doaj.org/article/8e51ad775d27471584c9fd0e0da0bc18
Autor:
Hanne S. Antila, Batuhan Kav, Markus S. Miettinen, Hector Martinez-Seara, Pavel Jungwirth, O. H. Samuli Ollila
Publikováno v:
Journal of Physical Chemistry B
The Journal of Physical Chemistry B
ChemRxiv : the Preprint Server for Chemistry
The Journal of Physical Chemistry B
ChemRxiv : the Preprint Server for Chemistry
Molecular simulations of biological membranes and proxies thereof are entering a new era characterized by several key aspects. Progress starts with the realization that the outcome of the simulations can only be as good as the underlying force field,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab48df2d7b827b0d4658573293c61f0
http://hdl.handle.net/10138/354440
http://hdl.handle.net/10138/354440
Publikováno v:
The Journal of Physical Chemistry B. 124:2994-3001
Membrane proteins travel along cellular membranes and reorient themselves to form functional oligomers and proteinlipid complexes. Following the Saffman-Delbruck model, protein-radius sets the rate of this diffusive motion. However, it is unclear how
Publikováno v:
Journal of Chemical Theory and Computation, 16(1), 738-748. AMER CHEMICAL SOC
Phosphatidylserine (PS) lipids are important signaling molecules and the most common negatively charged lipids in eukaryotic membranes. The signaling can be often regulated by calcium, but its interactions with PS headgroups are not fully understood.
Autor:
Jesper J. Madsen, Pavel Buslaev, Josef Melcr, Batuhan Kav, Fernando Favela-Rosales, Jukka Määttä, Markus S. Miettinen, O. H. Samuli Ollila, Tiago Mendes Ferreira, Matti Javanainen, Hanne S. Antila, Ricky Nencini, Ivan Gushchin, Thomas J. Piggot
Publikováno v:
Journal of Physical Chemistry B, 123(43), 9066-9079. AMER CHEMICAL SOC
Phosphatidylserine (PS) is a negatively charged lipid type commonly found in eukaryotic membranes, where it interacts with proteins via nonspecific electrostatic interactions as well as via specific binding. Moreover, in the presence of calcium ions,
Lipid monolayers provide our lungs and eyes their functionality and serve as proxy systems in biomembrane research. Therefore, lipid monolayers have been studied intensively including using molecular dynamics simulations, which are able to probe thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a2a2ac8b00085a43015e5e604e6e94
https://doi.org/10.26434/chemrxiv-2021-ws71h
https://doi.org/10.26434/chemrxiv-2021-ws71h
Autor:
Matti Javanainen, Salla I. Virtanen, Fernando Favela-Rosales, Chris Papadopoulos, Antonio Peón, Amélie Bacle, Anne M. Kiirikki, Patrick F.J. Fuchs, O. H. Samuli Ollila, Pavel Buslaev, Ángel Piñeiro, Rebeca García-Fandiño, Paula Milán Rodríguez, Tiago Mendes Ferreira, Markus S. Miettinen, Jesper J. Madsen, Josef Melcr, Ivan Gushchin, Thomas J. Piggot
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
Journal of the American Chemical Society, 143(34), 13701-13709. AMER CHEMICAL SOC
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
Journal of the American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
Journal of the American Chemical Society, 143(34), 13701-13709. AMER CHEMICAL SOC
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
International audience; Interest in lipid interactions with proteins and other biomolecules is emerging not only in fundamental biochemistry but also in the field of nanobiotechnology where lipids are commonly used, for example, in carriers of mRNA v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d9345531ed2d3d157ba5bfda9d2f8b
https://hal.sorbonne-universite.fr/hal-03355166/file/jacs.1c05549.pdf
https://hal.sorbonne-universite.fr/hal-03355166/file/jacs.1c05549.pdf