Zobrazeno 1 - 10
of 13
pro vyhledávání: '"O. H. Kehrhahn"'
Publikováno v:
International journal of clinical pharmacology, therapy, and toxicology. 21(7)
Seven normal male volunteers received an injection of 208 mg theophylline-anhydride (Solosin) each for 4 min, and a 225-mg single oral dose (Afonilum) on separate occasions. The concentration of unchanged theophylline was analyzed over a 24-h period
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fefc32b721b126b11513cf8aef1faa6c
https://pubmed.ncbi.nlm.nih.gov/6885204
https://pubmed.ncbi.nlm.nih.gov/6885204
Autor:
O. H. Kehrhahn, D. Hotz, E. Brode, M. Hollmann, V. Bühler, S. Kaumeier, H. Lietz, J. A. Schwarz, B. Stieren, J. Weymann, H. G. Hege
Publikováno v:
Kardiale Rhythmusstörungen ISBN: 9783642819872
Das Wissen uber die Pharmakokinetik und das metabolische Verhalten von Propafenon beim Menschen war bisher eingeschrankt, was hauptsachlich auf Schwierigkeiten hinsichtlich der Analyse und des Gebrauchs radioaktiv markierter Substanz zuruckzufuhren i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01604f3dee715a63c6b16c3a7fb7d216
https://doi.org/10.1007/978-3-642-81986-5_14
https://doi.org/10.1007/978-3-642-81986-5_14
Autor:
H, Kubinyi, O H, Kehrhahn
Publikováno v:
Journal of medicinal chemistry. 19(8)
The Fujita-Ban model and the classical Free-Wilson model are shown to be linearly related: the de novo group contributions obtained by one model are linear transformations of those obtained by the other model. An example is given to illustrate this l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28681df37f9929b825d9372aa2d4c13e
https://pubmed.ncbi.nlm.nih.gov/966251
https://pubmed.ncbi.nlm.nih.gov/966251
Autor:
D. Hotz, V. Bühler, M. Hollmann, S. Kaumeier, H. Lietz, J. Weymann, E. Brode, O. H. Kehrhahn, B. Stieren, J. A. Schwarz, H. G. Hege
Publikováno v:
Cardiac Arrhythmias ISBN: 9783642689284
Knowledge of the pharmacokinetic and metabolic behavior of propafenone in humans has been limited mainly by difficulties in analysis and in using radioactively labeled substances. In earlier studies by Wiebringhaus, Keller, and Blanke et al. in Dusse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::154f24f552c95e6e72c9650013f01dfa
https://doi.org/10.1007/978-3-642-68926-0_14
https://doi.org/10.1007/978-3-642-68926-0_14
Autor:
H, Kubinyi, O H, Kehrhahn
Publikováno v:
Arzneimittel-Forschung. 28(4)
The bilinear model, log 1/C = a log P--b log (betaP + 1) + c, is a new model for the qunatitative description of non-linear relationships between hydrophobic character and biological activity. In contrast to the parabolic Hansch model the bilinear mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59e1d68ae9bae7ff58cda34f96d65510
https://pubmed.ncbi.nlm.nih.gov/581935
https://pubmed.ncbi.nlm.nih.gov/581935
Publikováno v:
Arzneimittel-Forschung. 34(1)
Seven normal male volunteers each received an injection of 208 mg theophylline anhydride for 4 min, and a 185-mg single oral dose theophylline anhydride (Broncho-Afonilum) on separate occasions. The concentrations of unchanged theophylline was analyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b3bf9cab9573a043bf92557d3993e15
https://pubmed.ncbi.nlm.nih.gov/6538428
https://pubmed.ncbi.nlm.nih.gov/6538428
Publikováno v:
Arzneimittel-Forschung. 33(11)
A double-blind cross-over study was carried out in ten healthy volunteers to investigate whether there was possible propafenone (Rytmonorm) interaction with alcohol and whether series propafenone produced EEG changes. For this a series of performance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1193d21595366ba27680883549f064fe
https://pubmed.ncbi.nlm.nih.gov/6686456
https://pubmed.ncbi.nlm.nih.gov/6686456
Publikováno v:
Arzneimittel-Forschung. 31(9a)
The absolute bioavailability and pharmacokinetics of 4-amino-6-methoxy-1-phenyl-pyridazinium methyl sulfate (amesiniummetilsulfate, LU 1631, Regulton), in the following briefly called amezinium, were examined following i.v. injection (10 mg) and sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f08f3a630198780c070ba7cde460a869
https://pubmed.ncbi.nlm.nih.gov/7197980
https://pubmed.ncbi.nlm.nih.gov/7197980
Publikováno v:
Arzneimittel-Forschung. 33(5)
The pharmacokinetics of propafenone (Rytmonorm) was studied in 19 healthy volunteers. Propafenone was given intravenously (commercial ampoules of 70 mg) and orally in different doses (150, 300, 450 mg) and forms (solution, commercial film tablets). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c95f363f8b575a6518fd26ceafc70db1
https://pubmed.ncbi.nlm.nih.gov/6683556
https://pubmed.ncbi.nlm.nih.gov/6683556
Autor:
O H, Kehrhahn
Publikováno v:
Arzneimittel-Forschung. 23(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8abaf40938f7b07916cfb81d50279223
https://pubmed.ncbi.nlm.nih.gov/4147954
https://pubmed.ncbi.nlm.nih.gov/4147954