Zobrazeno 1 - 10
of 42
pro vyhledávání: '"O. Gefvert"'
Autor:
Bo Eriksson, Svante Nyberg, Mariëlle Eerdekens, O. Gefvert, Lars Helldin, Per Persson, Erik Mannaert, Annika Björner, Bart Remmerie
Publikováno v:
The International Journal of Neuropsychopharmacology. 8:27-36
Thirteen patients with schizophrenia received injections of 25, 50, or 75 mg of long-acting risperidone every 2 wk. Brain D2 receptor occupancy was assessed with [11C]raclopride 2 wk after the last (fifth) injection (day 71) in seven subjects and 2 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c14b37ed271ce0b322717d8c7c84d7
https://doi.org/10.1017/s1461145704004924
https://doi.org/10.1017/s1461145704004924
Autor:
Stephen D. Martin, O. Gefvert, W. Wolfgang Fleischhacker, Mariëlle Eerdekens, Wlodzimierz Chrzanowski, Keith Karcher, Pierre-Michel Llorca, Gary Remington
Publikováno v:
The Journal of Clinical Psychiatry. 64:1250-1257
Background: The long-term safety and efficacy of long-acting injectable risperidone, the first long-acting second-generation antipsychotic, were evaluated in stable patients with schizophrenia. Method: After a 2-week run-in period during which patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4216bd4cbd3457410b8169ca24823b33
https://doi.org/10.4088/jcp.v64n1017
https://doi.org/10.4088/jcp.v64n1017
Publikováno v:
Social Psychiatry and Psychiatric Epidemiology. 34:416-424
Background: The present study examined the prevalence of social phobia in the Swedish general population and demographic characteristics associated with this anxiety disorder. Methods: Data were obtained by means of a postal survey administrated to 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf25c3de78cd1cebf3fec46d4b564dfd
https://doi.org/10.1007/s001270050163
https://doi.org/10.1007/s001270050163
Publikováno v:
Scandinavian journal of psychology. 44(3)
Positron emission tomography (PET) has been shown to be of great importance in elucidating the mechanism of action of antipsychotic drugs. In psychotic patients L-[11C]DOPA PET has been used to demonstrate some differences in dopaminergic activity co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb0bf48ab939ce0fbae01a8e923e85b
https://pubmed.ncbi.nlm.nih.gov/12914593
https://pubmed.ncbi.nlm.nih.gov/12914593
Autor:
Bengt Långström, Leif Lindström, Frits-Axel Wiesel, Ing-Marie Wieselgren, T. Lundberg, Mats Bergström, O. Gefvert
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 11(2)
Objective: Quetiapine is a novel antipsychotic agent with many atypical features, including low D2 and higher 5HT2A affinity in vitro, low propensity to induce extra-pyramidal side effects and minimal effects on prolactin levels. The purpose of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba302e0d89ff77bb2749f07d77fbc110
https://pubmed.ncbi.nlm.nih.gov/11313155
https://pubmed.ncbi.nlm.nih.gov/11313155
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 20(1-2)
A sensitive and specific HPLC assay for the measurement of the antipsychotic compound quetiapine in human plasma has been developed and validated. The assay employs a three-step liquid–liquid extraction of quetiapine and its 7-hydroxylated and 7-hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07030b8d0bcc50f14074b9dd5f4814a6
https://pubmed.ncbi.nlm.nih.gov/10704032
https://pubmed.ncbi.nlm.nih.gov/10704032
Autor:
Gisela E. Hagberg, T. Lundberg, Mats Bergström, O. Gefvert, Bengt Långström, Per Hartvig, Leif Lindström
Publikováno v:
Biological Psychiatry
Background: The aim of the present study was to investigate dopamine synthesis in the brain of drug-free schizophrenic patients, not only in the striatum but also in extrastriatal areas like the prefrontal cortex, brain areas that for a long time has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc4652bd309a0490ea0ef66856f1f7f
https://pubmed.ncbi.nlm.nih.gov/10472420
https://pubmed.ncbi.nlm.nih.gov/10472420
Autor:
Bengt Långström, Gisela E. Hagberg, Frits-Axel Wiesel, Ing-Marie Wieselgren, Leif Lindström, Mats Bergström, O. Gefvert
Publikováno v:
Psychiatry Research: Neuroimaging
The occupancy of the atypical neuroleptic quetiapine (Seroquel) at the D2 dopamine receptor was investigated using the PET tracers [11C]raclopride and N-[11C]methylspiperone in a group of five schizophrenic patients. A steady-state treatment conditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2769e5ae359989a758990ae109e5bfea
https://pubmed.ncbi.nlm.nih.gov/9754439
https://pubmed.ncbi.nlm.nih.gov/9754439
Publikováno v:
Psychopharmacology. 135(2)
Quetiapine (Seroquel) is a novel antipsychotic with an atypical profile in animal models and a relatively short plasma half-life of 2.5 5 h. In the present study, we used PET to compare the time course of blockade of dopamine D2 and serotonin 5HT2 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2edaaa1a4d40d4158bbaa263b2f2e6
https://pubmed.ncbi.nlm.nih.gov/9497016
https://pubmed.ncbi.nlm.nih.gov/9497016
Autor:
G. Hagberg, M. Bergstrom, T. Lundberg, P. Hagstrom, Bengt Långström, P. Hartvig, O. Gefvert, Leif Lindström
Publikováno v:
Schizophrenia Research. 29:93-94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::024b474a4dbcf6a576e6c81f9a917443
https://doi.org/10.1016/s0920-9964(97)88535-0
https://doi.org/10.1016/s0920-9964(97)88535-0