Zobrazeno 1 - 10
of 32
pro vyhledávání: '"O. Garth Fitzhugh"'
Publikováno v:
Journal of AOAC INTERNATIONAL. 35:745-748
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6444b941f1da68f0b91f644e6eef98d
https://doi.org/10.1093/jaoac/35.3.745
https://doi.org/10.1093/jaoac/35.3.745
Publikováno v:
Journal of the American Pharmaceutical Association (Scientific ed.). 40:583-586
Data are given on the chronic oral toxicities of the synthetic sweetening agents, saccharin, sodium cyclohexyl sulfamate, dulcin, and P-4000. The results indicate that these four substances may be divided into a toxic group and a relatively nontoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56226aae95719137cce9a31db493230c
https://doi.org/10.1002/jps.3030401117
https://doi.org/10.1002/jps.3030401117
Publikováno v:
Journal of AOAC INTERNATIONAL. 35:741-745
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d4b4b2dcc1e25a08372bd1bb1229d74
https://doi.org/10.1093/jaoac/35.3.741
https://doi.org/10.1093/jaoac/35.3.741
Publikováno v:
Toxicology and Applied Pharmacology. 1:1-7
Dog plasma and red-cell cholinesterase determinations following the feeding of Dipterex, Chlorthion, methyl parathion, and Diazinon at several levels indicate that these materials are potent cholinesterase inhibitors. Dipterex, when fed at 500, 200,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a213c7872388a3a87d799c49b56a04c
https://doi.org/10.1016/0041-008x(59)90143-7
https://doi.org/10.1016/0041-008x(59)90143-7
Publikováno v:
Toxicology and Applied Pharmacology. 5:16-35
The results of two-year oral toxicity studies with rats at feeding levels of 2500, 1000, and 500 ppm and one-year studies with dogs at 5000, 1000, and 500 ppm for Yellow AB or Yellow OB have been presented. Subcutaneous injection studies with rats an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2786d2b65655f46ee502152c06f380
https://doi.org/10.1016/0041-008x(63)90079-6
https://doi.org/10.1016/0041-008x(63)90079-6
Publikováno v:
Toxicology and Applied Pharmacology. 3:696-706
3,6-Diaminofluoran, the ultimate metabolite of Rhodamine B (tetraethyl-3,6-diaminofluoran) exerted fewer toxic effects in rats than Rhodamine B. The LD50 (intravenous) for Rhodamine B was 89.5 mg/kg compared to and LD50 of 140.0 mg/kg for 3,6-diamino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bb7c1493359f9ff383a0544d97eb2a
https://doi.org/10.1016/0041-008x(61)90033-3
https://doi.org/10.1016/0041-008x(61)90033-3
Autor:
O. Garth Fitzhugh
Publikováno v:
Experimental Biology and Medicine. 40:11-15
Summary and ConclusionsOur experiments confirm the observations of Neale and Winter5 that xanthine has a protective action against carbon tetrachloride poisoning. The extent of the necrosis in the liver lobule is decreased by xanthine. Liver protecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3b00a874fad8afa3f48975e7817375c
https://doi.org/10.3181/00379727-40-10289
https://doi.org/10.3181/00379727-40-10289
Autor:
M.Jacqueline Verrette, Joseph McLaughlin, Mary K. Mutchler, Jean-Pierre Marliac, O. Garth Fitzhugh
Publikováno v:
Toxicology and Applied Pharmacology. 5:760-771
An evaluation of toxicity by injection of the chemical into the yolk sac of fertile eggs prior to incubation gave the following results: Water, propylene glycol, corn oil, peanut oil, isotonic saline solution, and isotonic glucose solution showed no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5692a5e3f428609caf84e0476945d4e5
https://doi.org/10.1016/0041-008x(63)90068-1
https://doi.org/10.1016/0041-008x(63)90068-1
Publikováno v:
Toxicology and Applied Pharmacology. 5:105-118
The results of two-year oral toxicity studies with Ponceau 3R using two strains of rats have been presented. Dosage levels were 5.0, 2.0, 1.0, and 0.5% for Osborne-Mendel rats and one dosage level of 2.0% for Bethesda Black rats. Preliminary results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3d45bec6afc3e05d442600bf328e4f
https://doi.org/10.1016/0041-008x(63)90085-1
https://doi.org/10.1016/0041-008x(63)90085-1
Autor:
Wm.I. Jones, Paul M. Jenner, O. Garth Fitzhugh, Ernest C. Hagan, J.G. Brouwer, Willis K. Webb, Eleanor L. Long
Publikováno v:
Toxicology and Applied Pharmacology. 7:18-24
Dihydrosafrole on chronic feeding produced benign and malignant esophageal tumors. Safrole is a hepatic carcinogen. Liver changes produced by isosafrole, safrole, and dihydrosafrole were of the same general type and included hepatic cell enlargement,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0db13c6d19d78404166f63f2e8f4d47
https://doi.org/10.1016/0041-008x(65)90069-4
https://doi.org/10.1016/0041-008x(65)90069-4